Terminal differentiation in vitro of patient-derived post-TMD megakaryoblastic AML cells

Annals of Hematology

Volumn 82, Issue 8, 2003, Pages 506-510

  Classen, Carl F ^a   Gnekow, A ^b   Debatin, K M ^a  

^a UNIVERSITY HOSPITAL ULM   (Germany)

^b KLINIKUM AUGSBURG   (Germany)

Author keywords

AML FAB M7; Differentiation; Down syndrome; TMD

Indexed keywords

ERYTHROCYTE ANTIGEN; FIBRINOGEN RECEPTOR; GLYCOPHORIN A; MYC PROTEIN; PHORBOL 13 ACETATE 12 MYRISTATE; THROMBOCYTE ANTIGEN; TRANSCRIPTION FACTOR GATA 1;

ACUTE MEGAKARYOCYTIC LEUKEMIA; ARTICLE; BLAST CELL; BLOOD ANALYSIS; BONE MARROW EXAMINATION; CANCER CELL; CANCER PATIENT; CELL DIFFERENTIATION; CELL LINEAGE; CELL SPECIFICITY; CELL STRUCTURE; DISEASE COURSE; DOWN REGULATION; DOWN SYNDROME; FLOW CYTOMETRY; GENE MUTATION; HUMAN; IN VITRO STUDY; MEGAKARYOCYTE; MYELOPROLIFERATIVE DISORDER; PHENOTYPE; PRESCHOOL CHILD; PRIORITY JOURNAL; REMISSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION;

ACUTE DISEASE; CELL DIFFERENTIATION; CELLS, CULTURED; CHILD, PRESCHOOL; FLOW CYTOMETRY; GLYCOPHORIN; HUMANS; LEUKEMIA, MYELOCYTIC, ACUTE; MEGAKARYOCYTES; MYELOPROLIFERATIVE DISORDERS; PHENOTYPE; PLATELET MEMBRANE GLYCOPROTEIN IIB; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TETRADECANOYLPHORBOL ACETATE;

EID: 0042355608     PISSN: 09395555     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00277-003-0692-3     Document Type: Article

References (13)

1. Berlanga O, Bobe R, Becker M, Murphy G, Leduc M, Bon C, Barry FA, Gibbins JM, Garcia P, Frampton J, Watson SP (2000) Expression of the collagen receptor glycoprotein VI during megakaryocyte differentiation. Blood 96:2740-2745
2. Buehrer BM, Bardes ES, Bell RM (1996) Protein kinase C-dependent regulation of human erythroleukemia (HEL) cell sphingosine kinase activity. Biochim Biophys Acta 1303:233-242
3. Cataldi A, Di Pietro R, Centurione L, Grilli A, Cutroneo G, Miscia S (2000) Phosphatidylinositol-3-kinase activation and atypical protein kinase C zeta phosphorylation characterize the DMSO signalling in erythroleukemia cells. Cell Signal 12:667-672
4. Classen CF, Fulda S, Friesen C, Debatin KM (1999) Decreased sensitivity of drug-resistant cells towards T cell cytotoxicity. Leukemia 13:410-418
5. Duchayne E, Fenneteau O, Pages MP, Sainty D, Arnoulet C, Dastugue N, Garand R, Flandrin G, Groupe Francais d'Hematologie Cellulaire, Groupe Francais de Cytogenetique Hematologique (2003) Acute megakaryoblastic leukaemia: a national clinical and biological study of 53 adult and childhood cases by the Groupe Francais d'Hematologie Cellulaire (GFHC). Leuk Lymphoma 44:49-58
6. Drexler HG, Matsuo Y (2000) Malignant hematopoietic cell lines: in vitro models for the study of natural killer cell leukemia-lymphoma. Leukemia 14:777-782
7. Han ZT, Zhu XX, Yang RY, Sun JZ, Tian GF, Liu XJ, Cao GS, Newmark HL, Conney AH, Chang RL (1998) Effect of intravenous infusions of 12-O-tetradecanoylphorbol-13-acetate (TPA) in patients with myelocytic leukemia: preliminary studies on therapeutic efficacy and toxicity. Proc Natl Acad Sci U S A 95:5357-5361
8. Hoffman B, Amanullah A, Shafarenko M, Liebermann DA (2002) The proto-oncogene c-myc in hematopoietic development and leukemogenesis. Oncogene 21:3414-3421
9. Kim MS, Lim WK, Cha JG, An NH, Yoo SJ, Park JH, Kim HM, Lee YM (2001) The activation of PI 3-K and PKC zeta in PMA-induced differentiation of HL-60 cells. Cancer Lett 171:79-85
10. Polski JM, Galambos C, Gale GB, Dunphy CH, Evans HL, Batanian JR (2002) Acute megakaryoblastic leukemia after transient myeloproliferative disorder with clonal karyotype evolution in a phenotypically normalneonate. J Pediatr Hematol Oncol 24:50-54
11. Taniguchi Y, London R, Schinkmann K, Jiang S, Avraham H (1999) The receptor protein tyrosine phosphatase, PTP-RO, is upregulated during megakaryocyte differentiation and is associated with the c-Kit receptor. Blood 94:539-549
12. Thomas X, Dombret H, Cordonnier C, Pigneux A, Gardin C, Guerci A, Vekhoff A, Sadoun A, Stamatoullas A, Fegueux N, Maloisel F, Cahn JY, Reman O, Gratecos N, Berthou C, Huguet F, Kotoucek P, Travade P, Buzyn A, de Revel T, Vilque JP, Naccache P, Chomienne C, Degos L, Fenaux P (2000) Treatment of relapsing acute promyelocytic leukemia by all-trans retinoic acid therapy followed by timed sequential chemotherapy and stem cell transplantation. APL Study Group, acute promyelocytic leukemia. Leukemia 14:1006-1013
13. Wechsler J, Greene M, McDevitt MA, Anastasi J, Karp JE, Le Beau MM, Crispino JD (2002) Acquired mutations in GATA1 in the megakaryoblastic leukemia of Down syndrome. Nat Genet 32:148-152