Utilidad clínica de la ratio psa libre / PSA total en el diagnóstico precoz del cáncer de próstata

Archivos Espanoles de Urologia

Volumn 53, Issue 4, 2000, Pages 333-341

  Pilar Laguna Pes, M ^a,b   Guinda Sevillano, Carlos ^a   Zazo Romojaro, Andrés ^a   Domínguez, Joaquín ^a   García Luzón, Anabella ^a   Borrego Hernando, Jaime ^a   Gimeno Collado, Alfonso ^a  

^a HOSPITAL GENERAL LA MANCHA CENTRO   (Spain)

^b NONE   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

PROSTATE SPECIFIC ANTIGEN;

AGED; ARTICLE; BLOOD; HUMAN; MALE; PREDICTION AND FORECASTING; PROSPECTIVE STUDY; PROSTATE TUMOR; SENSITIVITY AND SPECIFICITY; TIME;

AGED; HUMANS; MALE; PREDICTIVE VALUE OF TESTS; PROSPECTIVE STUDIES; PROSTATE-SPECIFIC ANTIGEN; PROSTATIC NEOPLASMS; SENSITIVITY AND SPECIFICITY; TIME FACTORS;

EID: 0042279785     PISSN: 00040614     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. WANG, MC.; VALENZUELA, L.A.; MURPHY, G.P. y cols.: "Purification of a human prostate specific antigen." Invest. Urol., 17: 159, 1979.
2. POLASCIK, T.J.; OESTERLING, J.E.; PARTIN, A.W.: "Prostate specific antigen: a decade of discovery-what we have learned and where we are going." J. Urol., 162: 293, 1999.
3. PARTIN, A.W.; CARTER, H.B.; CHAN, D.W. y cols.: "Prostate specific antigen in the staging of localized prostate cancer: influence of tumor differentiation, tumor volume and benign hyperplasia." J. Urol., 143: 747, 1990.
4. BENSON, M.H.; WHANG, I.S.; PANTUCK, A. y cols.: "Prostate specific antigen density: a means of distinguishing benign prostatic hypertrophy and prostate cancer." J. Urol., 147: 815, 1992.
5. OESTERLING, J.E.; JACOBSEN, S.J.; CHUTE, C.G. y cols.: "Serum prostate-specific antigen in a community-based population of healthy men: establishment of age-specific reference ranges". JAMA, 270: 860, 1993.
6. CARTER, H.B.; PEARSON, J.D.; METTER, J. y cols.: "Longitudinal evaluation of prostate-specific antigen levels in men with and without prostate diseases." JAMA, 267: 2215, 1992.
7. BABAIAN, R.J.: "Current status of enhancing the detection of prostate cancer." Prostate, 31: 204, 1997.
8. ZLOTTA, A.R.; DJAVAN, B.; MARBERGER, M. y cols.: "Prostate specific antigen density of the transition zone: a new effective parameter for prostate cancer prediction." J. Urol., 157: 1315, 1997.
9. OAKLEY, N.: "Clinical implications of prostate-specific antigen (PSA)." Current Opinion in Urology, 8: 401, 1998.
10. STENMAN, U.H.; LEINONEN, J.; ALFTHAN, H. y cols.: "A complex between prostate-specific antigen and α-1-antichymotrypsin is the major form of prostate-specific antigen in serum of patients with prostate cancer: assay of the complex improves clinical sensitivity for cancer." Cancer Res., 51: 222, 1991.
11. LILJA, H.; CHRISTENSSON, A.; DAHLEN, U. y cols.: "Prostate specific antigen in serum occurs predominantly in complex with α-1-antichymotrypsin." Clin. Chem., 37: 1618, 1991.
12. CHRISTENSSON, A.; LILJA, H.: " Complex formation between protein C inhibitor and prostate-specific antigen in vitro and in human semen." Eur. J. Biochem., 220: 45, 1990.
13. SOKOLL, L.J.; CHAN, D.W.: "Total, free and complexed PSA: analysis and clinical utility." J. Clin. Ligand Assay, 21: 171, 1998.
14. RITTENHOUSE, H.G.; FINLAY, J.A.; MIKOLAJCZYK, S.D. y cols.: "Human kallikrein 2 (hK2) and prostate specific antigen (PSA): two closely related, but distinct, kallikreins in the prostate." Crit. Rev. Clin. Lab. Sci., 53: 275, 1998.
15. CATALONA, W.J.; SMITH, D.S.; WOLFERT, R.L. y cols.: "Evaluation of percentage of free serum PSA to improve specificity of prostate cancer screening." JAMA, 274: 1214, 1995.
16. PARTIN, A.W.; CATALONA, W.J.; SOUTHWICK, P.C. y cols.: "Analysis of percent free prostate-specific antigen (PSA) for prostate cancer detection: influence of total PSA, prostate volume and age." Urol., 48: 55, 1996.
17. CATALONA, W.J.; RICHIE, J.P.; AHMANN, F.R. y cols.: "Comparison of digital rectal examination and serum prostate specific antigen in the early detection of prostate cancer: results of a multicenter clinical trial of 6,630 men." J. Urol., 151: 1283, 1994.
18. VASHI, A.R.; WOJNO, K.J.; HENDRICKS, W. y cols.: "Determination of the reflex-range and appropriate cutpoints for percent free prostate specific antigen in 413 men referred for prostatic evaluation using the AxSYM system." Urology, 49: 19, 1997.
19. MASTERS, J.G.; KEEGAN, P.E.; HIDRETH, A.J. y cols.: "Free/total PSA serum prostate-specific antigen ratio: how helpful is it in detecting prostate cancer." B.J.U. International, 81: 419, 1998.
20. COLLINS, G.N.; ALEXANDROU, K.; WYNN-DAVIES, A. y cols.: "Free prostate-specific antigen "in the field": a useful adjunct to standard clinical practice". B.J.U. International, 83: 1000, 1999.
21. SEAMAN, E.; WHANG, I.S.; OLSSON, C.A. y cols.: "PSA density (PSAD): role in patient evaluation and management." Urol. Clin. North Am., 20: 653, 1993.
22. BAZINET, M.; MESHREF, A.A.; TRUDEL, C. y cols.: "Prospective evaluation of prostate specific antigen density and systematic biopsies for early detection of prostatic carcinoma." Urology, 43: 44, 1994.
23. PERROTTI, M.; FARHANG, R.; RUSSO, P. y cols.: "Early prostate cancer detection and potential for surgical cure in men with poorly differentiated tumors." Urology, 52: 106, 1998.
24. TERRIS, M.K.; STAMEY, T.A.: "Determination of prostate volume by transrectal ultrasound." J. Urol., 145: 984, 1991.
25. BENSON, M.C.; WHANG, I.S.; OLSSON, C.A. y cols.: "The use of prostate specific antigen density to enhance the predictive value of intermediate levels of serum prostate specific antigen." J. Urol., 147: 817, 1992.
26. LUDERER, A.A.; CHEN, Y.T.; SORIANO, T.F. y cols.: "Measurement of the proportion of free to total prostate specific antigen improves diagnostic performance of prostate specific antigen in the diagnostic gray zone of total prostate-specific antigen". Urology, 46: 187, 1995.
27. CATALONA, W.J.; PARTIN, A.W.; SLAWIN, K.M. y cols.: "A multicenter clinical trial evaluation of free PSA in the differentiation of prostate cancer from benign disease." J. Urol., part 2, 157: 111, abst. 434, 1997.
28. STENMAN, H.; LEINONEN, J.; ZHANG, W.M. y cols.: "The clinical importance of free prostate-specific antigen (PSA)." Current Opinion in Urology, 8: 393, 1998.
29. KEETCH, D.W.; CATALONA, W.J.; SMITH, D.S.: "Serial prostate biopsies in men with persistently elevated serum prostate specific antigen values". J. Urol., 151: 1571, 1994.
30. VELTRI, R.W.; MILLER, M.C.; "Free/total PSA ratio improves differentiation of benign and malignant disease of the prostate: critical analysis of two different test populations". Urology, 53: 736, 1999.
31. BANGMA, C.H.; RIETBERGEN, J.B.W.; KRANSE, R. y cols.: "The free to total prostate-specific antigen ratio improves the specificity of prostate specific antigen in screening for prostate cancer in the general population." J. Urol., 57: 2191, 1997.