A comparison of phosphonothioic acids with phosphonic acids as phosphatase inhibitors

Journal of Medicinal Chemistry

Volumn 46, Issue 17, 2003, Pages 3703-3708

  Swierczek, Krzysztof ^a,b   Pandey, Arti S ^a   Peters, John W ^c   Hengge, Alvan C ^a  

^a UTAH STATE UNIVERSITY   (United States)

^b SILESIAN UNIVERSITY OF TECHNOLOGY   (Poland)

^c MONTANA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE; ANION; BACTERIAL ENZYME; ESTER DERIVATIVE; ORGANOPHOSPHATE; OXYGEN; PHOSPHATASE; PHOSPHATE; PHOSPHONIC ACID DERIVATIVE; PHOSPHONOTHIOIC ACID DERIVATIVE; PHOSPHOPROTEIN PHOSPHATASE 2C; PHOSPHOROTHIOIC ACID DERIVATIVE; PHOSPHORUS DERIVATIVE; PLACENTA ENZYME; PROTEIN PHOSPHATASE LAMBDA; PROTEIN SERINE THREONINE PHOSPHATASE; PROTEIN TYROSINE PHOSPHATASE; SULFUR; THIOL DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING KINETICS; CHEMICAL BOND; CHEMICAL REACTION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DRUG BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; ELECTRIC POTENTIAL; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME INHIBITION; ENZYME SUBSTRATE; ESCHERICHIA COLI; HUMAN; NONHUMAN; PKA; PLACENTA; STEREOSPECIFICITY; STRUCTURE ANALYSIS; SUBSTITUTION REACTION; TECHNIQUE; YERSINIA;

ALKALINE PHOSPHATASE; ENZYME INHIBITORS; ESCHERICHIA COLI; HUMANS; ORGANOPHOSPHORUS COMPOUNDS; PHOSPHONIC ACIDS; PHOSPHOPROTEIN PHOSPHATASE; PLACENTA; PROTEIN-TYROSINE-PHOSPHATASE; STRUCTURE-ACTIVITY RELATIONSHIP; YERSINIA;

EID: 0042231985     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm030106f     Document Type: Article

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