Vitamin E and heart disease controversy: Two major studies; One common flaw

Journal of Orthomolecular Medicine

Volumn 18, Issue 2, 2003, Pages 59-60

  Burford Mason, Aileen ^a  

^a NONE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOCOPHEROL; ALPHA TOCOTRIENOL; ANTIOXIDANT; ASCORBIC ACID; BETA CAROTENE; BETA TOCOPHEROL; BETA TOCOTRIENOL; DELTA TOCOPHEROL; DELTA TOCOTRIENOL; ESTROGEN; GAMMA TOCOPHEROL; GAMMA TOCOTRIENOL; UNCLASSIFIED DRUG; XANTHOPHYLL;

ANGIOGRAPHY; DOSE RESPONSE; DRUG ABSORPTION; DRUG FORMULATION; DRUG POTENCY; EDITORIAL; FINLAND; FOLLOW UP; HEART DISEASE; HEART PROTECTION; HUMAN; VITAMIN SUPPLEMENTATION;

EID: 0042168732     PISSN: 03170209     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Editorial

References (11)

1. Jang Y, Lee JH, Kim OY, et al: Consumption of whole grain and legume powder reduces insulin demand, lipid peroxidation, and plasma homocysteine concentrations in patients with coronary artery disease: randomized controlled clinical trial. Arterioscler Thromb Vasc Biol, 2001 Dec; 21(12): 2065-71.
2. Iuliano L, Micheletta F, Maranghi M, et al: Bioavailability of vitamin E as function of food intake in healthy subjects: effects on plasma peroxide-scavenging activity and cholesterol-oxidation products. Arterioscler Thromb Vasc Biol, 2001 Oct; 21(10): E34-7.
3. Heart Protection Study Collaborative Group. MRC/BHF Heart Protection Study of antioxidant supplementation in 20,536 high risk individuals: a randomized placebo-controlled trial. Lancet, 2002; 360: 23-33.
4. Waters D, Alderman E, Hsia J et al: Effects of Hormone Replacement Therapy and Antioxidant Vitamin Supplements on Coronary Atherosclerosis in Postmenopausal Women. JAMA, 2002; 288: 2432-2440
5. Hanes, N, WAVE correspondent. Personal Communication
6. Burton GW, Traber MG, Acuff RV, et al: "Human plasma and tissue a-tocopherol concentrations in response to supplementation with deuterated natural and synthetic vitamin E," Am J Clin Nutr, 1998; 67: 669-684.
7. Moyad MA, Brumfield SK, Pienta KJ Vitamin E, alpha- and gamma-tocopherol, and prostate cancer. Semin Urol Oncol, 1999 May: 17(2): 85-90.
8. Olmedilla B, Granado F, Southon S et al: A European multicentre, placebo-controlled supplementation study with alpha-tocopherol, carotene-rich palm oil, lutein or lycopene: analysis of serum responses. Clin Sci(Lond). 2002 Apr; 102(4): 447-56.
9. Jiang Q, Christen S, Shigenaga MK, Ames BN: Gamma-tocopherol, the major form of vitamin E in the US diet, deserves more attention. Am J Clin Nutr, 2001 Dec; 74(6): 714-22.
10. Liu M, Wallmon A, Olsson-Mortlock C, et al. Mixed tocopherols inhibit platelet aggregation in humans: potential mechanisms. Am J Clin Nutr, 2003 Mar; 77(3): 700-6.
11. Xue KX, Wu JZ, Ma GJ, Yuan S, Qin HL. Comparative studies on genotoxicity and antigenotoxicity of natural and synthetic beta-carotene stereoisomers. Mutat Res, 1998 Oct 12; 418(2-3): 73-8.