Mutational analysis of the R peptide cleavage site of Moloney murine leukaemia virus envelope protein

Journal of General Virology

Volumn 84, Issue 8, 2003, Pages 2253-2257

  Kubo, Yoshinao ^a,b   Amanuma, Hiroshi ^a  

^a RIKEN   (Japan)

^b NAGASAKI UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; MUTANT PROTEIN; PEPTIDE; PROTEINASE; VIRUS ENVELOPE PROTEIN;

ANIMAL CELL; CELL FUSION; CELL MEMBRANE; CELL STRAIN 3T3; CONTROLLED STUDY; GENETIC TRANSDUCTION; HOST CELL; MATURATION; MEMBRANE FUSION; MOLONEY LEUKEMIA ONCOVIRUS; MUTATIONAL ANALYSIS; NONHUMAN; PLASMID; PRIORITY JOURNAL; PROTEIN DEGRADATION; SHORT SURVEY; VIRION; VIRUS ENVELOPE;

3T3 CELLS; AMINO ACID SUBSTITUTION; ANIMALS; CELL LINE; GENETIC VECTORS; GIANT CELLS; MEMBRANE FUSION; MICE; MOLONEY MURINE LEUKEMIA VIRUS; OLIGOPEPTIDES; TRANSDUCTION, GENETIC; VIRAL ENVELOPE PROTEINS;

ANIMALIA; MOLONEY MURINE LEUKEMIA VIRUS; MURINAE; ONCOVIRINAE; RNA VIRUSES;

EID: 0042167361     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/vir.0.19126-0     Document Type: Short Survey

References (35)

1. Aguilar, H. C., Anderson, W. F. & Cannon, P. M. (2003). Cytoplasmic tail of Moloney murine leukemia virus envelope protein influences the conformation of the extracellular domain: implications for mechanism of action of the R peptide. J Virol 77, 1281-1291.
2. Albritton, L. M., Tseng, L., Scadden, D. & Cunningham, J. M. (1989). A putative murine ecotropic retrovirus receptor gene encodes a multiple membrane-spanning protein and confers susceptibility to virus infection. Cell 57, 659-666.
3. Battini, J.-L., Heard, J. M. & Danos, O. (1992). Receptor choice determinants in the envelope glycoproteins of amphotropic, xenotropic, and polytropic murine leukemia viruses. J Virol 66, 1468-1475.
4. Bobkova, M., Stitz, J., Engelstadter, M., Cichutek, K. & Buchholz, C. J. (2002). Identification of R-peptides in envelope proteins of C-type retroviruses. J Gen Virol 83, 2241-2246.
5. Boross, P., Bagossi, P., Copeland, T. D., Oroszlan, S., Louis, J. M. & Tozser, J. (1999). Effect of substrate residues on the P2′ preference of retroviral proteinases. Eur J Biochem 264, 921-929.
6. Brody, B. A., Rhee, S. G. & Hunter, E. (1994). Postassembly cleavage of a retroviral glycoprotein cytoplasmic domain removes a necessary incorporation signal and activates fusion activity. J Virol 68, 4620-4627.
7. Cheng, S., Fockler, C., Barnes, W. M. & Higuchi, R. (1994). Effective amplification of long targets from cloned inserts and human genomic DNA. Proc Natl Acad Sci U S A 91, 5695-5699.
8. Cosset, F.-L., Takeuchi, Y., Battini, J.-L., Weiss, R. A. & Collins, M. K. L. (1995). High-titer packaging cells producing recombinant retroviruses resistant to human serum. J Virol 69, 7430-7436.
9. Davey, R. A., Zuo, Y. & Cunningham, J. M. (1999). Identification of a receptor-binding pocket on the envelope protein of Friend murine leukemia virus. J Virol 73, 3758-3763.
10. Granowitz, C., Berkowitz, R. D. & Goff, S. P. (1996). Mutations affecting the cytoplasmic domain of the Moloney murine leukemia virus envelope protein: rapid reversion during replication. Virus Res 41, 25-42.
11. Green, N., Shinnick, T. M., Witte, O., Ponticelli, A., Sutcliffe, J. G. & Lerner, R. A. (1981). Sequence-specific antibodies show that maturation of Moloney leukemia virus envelope polyprotein involves removal of a COOH-terminal peptide. Proc Natl Acad Sci U S A 78, 6023-6027.
12. Henderson, L. E., Sowder, R., Copeland, T. D., Smythers, G. & Oroszlan, S. (1984). Quantitative separation of murine leukemia Virus proteins by reversed-phase high-pressure liquid chromatography reveals newly described Gag and Env cleavage products. J Virol 52, 492-500.
13. Higuchi, R., Krummel, B. & Saiki, R. K. (1988). A general method of in vitro preparation and specific mutagenesis of DNA fragments: study of protein and DNA interactions. Nucleic Acids Res 16, 7351-7367.
14. Januszeski, M. M., Cannon, P. M., Chen, D., Rozenberg, Y. & Anderson, W. F. (1997). Functional analysis of the cytoplasmic tail of Moloney murine leukemia virus envelope protein. J Virol 71, 3613-3619.
15. Jones, J. S. & Risser, R. (1993). Cell fusion induced by the murine leukemia virus envelope glycoprotein. J Virol 67, 67-74.
16. Kiernan, R. E. & Freed, E. O. (1998). Cleavage of the murine leukemia virus transmembrane Env protein by human immunodeficiency virus type 1 protease: transdominant inhibition by matrix mutations. J Virol 72, 9621-9627.
17. Kubo, Y., Kakimi, K., Higo, K., Wang, L., Kobayashi, H., Kuribayashi, K., Masuda, T., Hirama, T. & Ishimoto, A. (1994). The p15gag and p12gag regions are both necessary for the pathogenicity of the murine AIDS virus. J Virol 68, 5532-5537.
18. Kubo, Y., Ono, T., Ogura, M., Ishimoto, A. & Amanuma, H. (2002). A glycosylation-defective variant of the ecotropic murine retrovirus receptor is expressed in rat XC cells. Virology 303, 338-344.
19. Li, M., Yang, C. & Compans, R. W. (2001). Mutations in the cytoplasmic tail of murine leukemia virus envelope protein suppress fusion inhibition by R peptide. J Virol 75, 2337-2344.
20. MacKrell, A. J., Soong, N. W., Curtis, C. M. & Anderson, W. F. (1996). Identification of a subdomain in the Moloney murine leukemia virus envelope protein involved in receptor binding. J Virol 70, 1768-1774.
21. Melikyan, G. B., Markosyan, R. M., Brener, S. A., Rozenberg, Y. & Cohen, F. S. (2000). Role of the cytoplasmic tail of ecotropic Moloney murine leukemia virus Env protein in fusion pore formation. J Virol 74, 447-455.
22. Menendez-Arias, L., Gotte, D. & Oroszlan, S. (1993). Moloney murine leukemia virus protease: bacterial expression and characterization of the purified enzyme. Virology 196, 557-563.
23. Menendez-Arias, L., Weber, I. T., Soss, J., Harrison, R. W., Gotte, D. & Oroszlan, S. (1994). Kinetic and modeling studies of subsites S4-S3′ of Moloney murine leukemia virus protease. J Biol Chem 269, 16795-16801.
24. Ott, D. & Rein, A. (1992). Basis for receptor specificity of nonecotropic murine leukemia virus surface glycoprotein gp70SU. J Virol 66, 4632-4638.
25. Ragheb, J. A. & Anderson, W. F. (1994). pH-independent murine leukemia virus ecotropic envelope-mediated cell fusion: implications for the role of the R peptide and p12E TM in viral entry. J Virol 68, 3220-3231.
26. Rein, A., Mirro, J., Haynes, J. G., Ernst, S. M. & Nagashima, K. (1994). Function of the cytoplasmic domain of a retroviral transmembrane protein: p15E-p12E cleavage activates the membrane fusion capability of the routine leukemia virus Env protein. J Virol 68, 1773-1781.
27. Rice, N. R., Henderson, L. E., Sowder, R. C., Copeland, T. D., Oroszlan, S. & Edwards, J. F. (1990). Synthesis and processing of the transmembrane envelope protein of equine infectious anemia virus. J Virol 64, 3770-3778.
28. Rothenberg, S. M., Olsen, M. N., Laurent, L. C., Crowley, R. A. & Brown, P. O. (2001). Comprehensive mutational analysis of the Moloney murine leukemia virus envelope protein. J Virol 75, 11851-11862.
29. Schagger, H. & von Jagow, G. (1987). Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa. Anal Biochem 166, 368-379.
30. Schultz, A. & Rein, A. (1985). Maturation of murine leukemia virus Env proteins in the absence of other viral proteins. Virology 145, 335-339.
31. Thomas, A., Gray, K. D. & Roth, M. J. (1997). Analysis of mutations within the cytoplasmic domain of the Moloney murine leukemia virus transmembrane protein. Virology 227, 305-313.
32. Yang, C. & Compans, R. W. (1996). Analysis of the cell fusion activities of chimeric simian immunodeficiency virus-murine leukemia virus envelope proteins: inhibitory effects of the R peptide. J Virol 70, 248-254.
33. Yang, C. & Compans, R. W. (1997). Analysis of the routine leukemia virus R peptide: delineation of the molecular determinants which are important for its fusion inhibition activity. J Virol 71, 8490-8496.
34. Zavorotinskaya, T. & Albritton, L. M. (1999). A hydrophobic patch in ecotropic murine leukemia virus envelope protein is the putative binding site for a critical tyrosine residue on the cellular receptor. J Virol 73, 10164-10172.
35. Zhao, Y., Zhu, L., Benedict, C. A., Chen, D., Anderson, W. F. & Cannon, P. M. (1998). Functional domains in the retroviral transmembrane protein. J Virol 72, 5392-5398.