Mutations in the cytoplasmic tail of murine leukemia virus envelope protein suppress fusion inhibition by R peptide

Journal of Virology

Volumn 75, Issue 5, 2001, Pages 2337-2344

  Li, M ^a   Yang, C ^a   Compans, R W ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; FLUORESCENT DYE; PEPTIDE; R PEPTIDE; UNCLASSIFIED DRUG; VIRUS ENVELOPE PROTEIN;

ARTICLE; CONTROLLED STUDY; DNA FLANKING REGION; ENZYME ACTIVITY; GENE INSERTION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MEMBRANE FUSION; MURINE LEUKEMIA VIRUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN EXPRESSION; SYNCYTIUM; VIROGENESIS; VIRUS MUTATION;

AMINO ACID SEQUENCE; ANIMALS; CELL LINE; HELA CELLS; HUMANS; LEUKEMIA VIRUS, MURINE; MEMBRANE FUSION; MICE; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PEPTIDE FRAGMENTS; VIRAL ENVELOPE PROTEINS;

EID: 0035121379     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.75.5.2337-2344.2001     Document Type: Article

References (53)

1. Truncation of the COOH-terminal region of the paramyxovirus SV5 fusion protein leads to hemifusion but not complete fusion
2. Structure of influenza haemagglutinin at the pH of membrane fusion
3. Core structure of gp41 from the HIV envelope glycoprotein
4. Methodologies in the study of cell-cell fusion
5. Use of fluorescent dyes in the determination of adherence of human leukocytes to endothelial cells and the effect of fluorochromes on cellular function
6. Influence of transmembrane domains on the fusogenic abilities of human and murine leukemia retrovirus envelopes
7. What studies of fusion peptides tell us about viral envelope glycoprotein-mediated membrane fusion
8. Glycine insertion in the hinge region of lactose repressor protein alters DNA binding
9. Retrovirus envelope domain at 1.7 angstrom resolution
10. Use of a hybrid vaccinia virus-T7 RNA polymerase system for expression of target genes
11. Detection of a fusion peptide sequence in the transmembrane protein of human immunodeficiency virus
12. Mutational analysis of the envelope gene of Moloney murine leukemia virus
13. Sequence-specific antibodies show that maturation of Moloney leukemia virus envelope polyprotein involves removal of a COOH-terminal peptide
14. Fluorescence method for measuring the kinetics of fusion between biological membranes
15. Structure-based identification of an inducer of the low-pH conformational change in the influenza virus hemagglutinin: Irreversible inhibition of infectivity
16. Functional analysis of the cytoplasmic tail of Moloney murine leukemia virus envelope protein
17. Helix packing in polytopic membrane proteins: Role of glycine in transmembrane helix association
18. Cell fusion induced by the murine leukemia virus envelope glycoprotein
19. Lipid-anchored influenza hemagglutinin promotes hemifusion, not complete fusion
20. Nucleotide sequence of the envelope gene of Friend murine leukemia virus
21. Glycosylation and processing of the human immunodeficiency virus type 1 envelope protein
22. Biogenetic pathways of plasma membrane proteins in Caco-2, a human intestinal epithelial cell line
23. CARE-LASS (calcein-release-assay), an improved fluorescence-based test system to measure cytotoxic T lymphocyte activity
24. Characteristics of self-quenching of the fluorescence of lipid-conjugated rhodamine in membranes
25. The pH independence of mammalian retrovirus infection
26. Role of the cytoplasmic tail of ecotropic Moloney murine leukemia virus Env protein in fusion pore formation
27. GPI-anchored influenza hemagglutinin induces hemifusion to both red blood cell and planar bilayer membranes
28. Dilation of the human immunodeficiency virus-1 envelope glycoprotein fusion pore revealed by the inhibitory action of a synthetic peptide from gp41
29. Role of the membrane-proximal domain in the initial stages of human immunodeficiency virus type 1 envelope glycoprotein-mediated membrane fusion
30. Elongation of the cytoplasmic tail interferes with the fusion activity of influenza virus hemagglutinin
31. Palmitoylation of the intracytoplasmic R peptide of the transmembrane envelope protein in Moloney murine leukemia virus
32. An improved fluorescence assay for the determination of lymphocyte-mediated cytotoxicity using flow cytometry
33. pH-independent murine leukemia virus ecotropic envelope-mediated cell fusion: Implications for the role of the R peptide and p12E TM in viral entry
34. Function of the cytoplasmic domain of a retroviral transmembrane protein: p15E-p2E cleavage activates the membrane fusion capability of the murine leukemia virus Env protein
35. Cell fusion activity of the simian immunodeficiency virus envelope protein is modulated by the intracytoplasmic domain
36. Prediction of protein secondary structure at better than 70% accuracy
37. Bacterial proteins with N-terminal leader sequences resembling mitochondrial targeting sequences of eukaryotes
38. Maturation of murine leukemia virus env proteins in the absence of other viral proteins
39. Effects of cytoplasmic domain length on cell surface expression and syncytium-forming capacity of the simian immunodeficiency virus envelope glycoprotein
40. Truncation of the cytoplasmic domain of the simian immunodeficiency virus envelope glycoprotein alters the conformation of the external domain
41. The role of the membrane-spanning domain sequence in glycoprotein-mediated membrane fusion
42. Analysis of mutations within the cytoplasmic domain of the Moloney murine leukemia virus transmembrane protein
43. Crystal structure of the Ebola virus membrane fusion subunit, GP2, from the envelope glycoprotein ectodomain
44. Structural basis for membrane fusion by enveloped viruses
45. Membrane fusion
46. Membrane fusion: The influenza paradigm
47. Viral membrane fusion proteins
48. Structure of the murine leukemia virus envelope glycoprotein precursor
49. Analysis of the cell fusion activities of chimeric simian immunodeficiency virus-murine leukemia virus envelope proteins: Inhibitory effects of the R peptide
50. Analysis of the murine leukemia virus R peptide: Delineation of the molecular determinants which are important for its fusion inhibition activity
51. Differences in the role of the cytoplasmic domain of human parainfluenza virus fusion proteins
52. Functional domains in the retroviral transmembrane protein
53. Intermediates in membrane fusion