-
1
-
-
0030960653
-
CYP450 4A and 2E1 expression in human kidney microsomes
-
Amet Y., Berthou F., Fournier G., Dreano Y., Bardou L., Cledes J., Menez J.F. CYP450 4A and 2E1 expression in human kidney microsomes. Biochem. Pharmacol. 53:1997;765-771.
-
(1997)
Biochem. Pharmacol.
, vol.53
, pp. 765-771
-
-
Amet, Y.1
Berthou, F.2
Fournier, G.3
Dreano, Y.4
Bardou, L.5
Cledes, J.6
Menez, J.F.7
-
2
-
-
0027430736
-
Effect of deoxyribonucleic acid protamination on fluorochrome staining and in situ nick-translation of murine and human mature spermatozoa
-
Bianchi P.G., Manicardi G.C., Bizzarro D., Bianchi U., Sakkas D. Effect of deoxyribonucleic acid protamination on fluorochrome staining and in situ nick-translation of murine and human mature spermatozoa. Biol. Reprod. 49:1993;1083-1088.
-
(1993)
Biol. Reprod.
, vol.49
, pp. 1083-1088
-
-
Bianchi, P.G.1
Manicardi, G.C.2
Bizzarro, D.3
Bianchi, U.4
Sakkas, D.5
-
3
-
-
0024097735
-
Pathophysiology of heme synthesis
-
Muller-Eberhard U. New York: Hospital-Cornell Medical Center
-
Bottomley S.S., Muller-Eberhard U. Pathophysiology of heme synthesis. Muller-Eberhard U. Seminar in Hematology. 25:1988;282-302 Hospital-Cornell Medical Center, New York.
-
(1988)
Seminar in Hematology
, vol.25
, pp. 282-302
-
-
Bottomley, S.S.1
Muller-Eberhard, U.2
-
4
-
-
0035063639
-
Halothane-induced liver injury in outbred guinea pigs: Role of trifluoroacetylated protein adducts in animal susceptibility
-
Bourdi M., Amouzadeh H.R., Rushmore T.H., Pohl L.R. Halothane-induced liver injury in outbred guinea pigs: role of trifluoroacetylated protein adducts in animal susceptibility. Chem. Res. Toxicol. 14:2001;362-370.
-
(2001)
Chem. Res. Toxicol.
, vol.14
, pp. 362-370
-
-
Bourdi, M.1
Amouzadeh, H.R.2
Rushmore, T.H.3
Pohl, L.R.4
-
5
-
-
0017122331
-
Effects of trace anaesthetic gases on behavioural performance of volunteers
-
Bruce D.L., Bach M.J. Effects of trace anaesthetic gases on behavioural performance of volunteers. Br. J. Anaesth. 48:1976;871-876.
-
(1976)
Br. J. Anaesth.
, vol.48
, pp. 871-876
-
-
Bruce, D.L.1
Bach, M.J.2
-
6
-
-
0026614994
-
The determination of ε-amino groups in soluble and poorly soluble proteinaceous materials by a spectrophotometric method using trinitrobenzenesulfonic acid
-
Bubnis W.A., Ofner C.M. III. The determination of ε-amino groups in soluble and poorly soluble proteinaceous materials by a spectrophotometric method using trinitrobenzenesulfonic acid. Anal. Biochem. 207:1992;129-133.
-
(1992)
Anal. Biochem.
, vol.207
, pp. 129-133
-
-
Bubnis, W.A.1
Ofner C.M. III2
-
7
-
-
0026675192
-
The calcium-binding protein calreticulin is covalently modified in rat liver by a reactive metabolite of the inhalation anesthetic halothane
-
Butler L.E., Thomassen D., Martin J.L., Martin B.M., Kenna J.G., Pohl L.R. The calcium-binding protein calreticulin is covalently modified in rat liver by a reactive metabolite of the inhalation anesthetic halothane. Chem. Res. Toxicol. 5:1992;406-410.
-
(1992)
Chem. Res. Toxicol.
, vol.5
, pp. 406-410
-
-
Butler, L.E.1
Thomassen, D.2
Martin, J.L.3
Martin, B.M.4
Kenna, J.G.5
Pohl, L.R.6
-
8
-
-
0022492548
-
The extent of metabolism of inhaled anesthetics in humans
-
Carpenter R.L., Eger E.I. II, Johnson B.H., Unadkat J.D., Sheiner L.B. The extent of metabolism of inhaled anesthetics in humans. Anesthesiology. 65:1986;201-205.
-
(1986)
Anesthesiology
, vol.65
, pp. 201-205
-
-
Carpenter, R.L.1
Eger E.I. II2
Johnson, B.H.3
Unadkat, J.D.4
Sheiner, L.B.5
-
9
-
-
0002507772
-
ELISA and related enzyme immunoassays
-
Catty D. Oxford: Oxford University Press
-
Catty D., Raykundalia C. ELISA and related enzyme immunoassays. Catty D. Antibodies: A Practical Approach. II:1989;97-154 Oxford University Press, Oxford.
-
(1989)
Antibodies: A Practical Approach
, vol.2
, pp. 97-154
-
-
Catty, D.1
Raykundalia, C.2
-
10
-
-
79961146838
-
Prognosis for sperm fertilizability: Analysis of different variables in men
-
Check J.H., Check M.L., Katsoff D. Prognosis for sperm fertilizability: analysis of different variables in men. Arch. Androl. 48:2002;73-83.
-
(2002)
Arch. Androl.
, vol.48
, pp. 73-83
-
-
Check, J.H.1
Check, M.L.2
Katsoff, D.3
-
11
-
-
0031106284
-
Contemporary issues in toxicology: Selective covalent binding and target organ toxicity
-
Cohen S.D., Pumford N.R., Khairallah E.D., Boekelheide K., Pohl L.R., Amouzadeh H.R., Hinson J.A. Contemporary issues in toxicology: selective covalent binding and target organ toxicity. Toxicol. Appl. Pharmacol. 143:1997;1-12.
-
(1997)
Toxicol. Appl. Pharmacol.
, vol.143
, pp. 1-12
-
-
Cohen, S.D.1
Pumford, N.R.2
Khairallah, E.D.3
Boekelheide, K.4
Pohl, L.R.5
Amouzadeh, H.R.6
Hinson, J.A.7
-
14
-
-
0020452109
-
Hepatic microsomal enzyme function in technicians and anesthesiologists exposed to halothane and nitrous oxide
-
Dossing M., Weihe P. Hepatic microsomal enzyme function in technicians and anesthesiologists exposed to halothane and nitrous oxide. Int. Arch. Occup. Environ. Health. 51:1982;91-98.
-
(1982)
Int. Arch. Occup. Environ. Health
, vol.51
, pp. 91-98
-
-
Dossing, M.1
Weihe, P.2
-
15
-
-
0010730895
-
Identification of cytochrome P450 2E1 in the rat efferent ducts and epididymis of the rat
-
DuTeaux S.B., Miller M.G. Identification of cytochrome P450 2E1 in the rat efferent ducts and epididymis of the rat. Toxicologist. 60:2001;385.
-
(2001)
Toxicologist
, vol.60
, pp. 385
-
-
DuTeaux, S.B.1
Miller, M.G.2
-
18
-
-
0029786269
-
Cytochrome P450 2E1 is a cell surface autoantigen in halothane hepatitis
-
Eliasson E., Kenna J.G. Cytochrome P450 2E1 is a cell surface autoantigen in halothane hepatitis. Mol. Pharmacol. 50:1996;573-582.
-
(1996)
Mol. Pharmacol.
, vol.50
, pp. 573-582
-
-
Eliasson, E.1
Kenna, J.G.2
-
19
-
-
0042339562
-
The reversible masking of amino groups in ribonuclease and its possible usefulness in the synthesis of the protein
-
Goldberger R.F., Anfinsen C.B. The reversible masking of amino groups in ribonuclease and its possible usefulness in the synthesis of the protein. Biochemistry. 1:1962;401-405.
-
(1962)
Biochemistry
, vol.1
, pp. 401-405
-
-
Goldberger, R.F.1
Anfinsen, C.B.2
-
20
-
-
0027220076
-
Mechanisms of halothane toxicity: Novel insights
-
Gut J., Christen U., Huwyler J. Mechanisms of halothane toxicity: novel insights. Pharmacol. Ther. 58:1993;133-155.
-
(1993)
Pharmacol. Ther.
, vol.58
, pp. 133-155
-
-
Gut, J.1
Christen, U.2
Huwyler, J.3
-
21
-
-
0029963099
-
Intraobserver, interobserver variation of sperm critical morphology: Comparison of examiner and computer-assisted analysis
-
Hoffman G.E., Santilli B.A., Kindig S., Scott R.T., Johnson C.A. Intraobserver, interobserver variation of sperm critical morphology: comparison of examiner and computer-assisted analysis. Fert. Steril. 65:1996;1021-1025.
-
(1996)
Fert. Steril.
, vol.65
, pp. 1021-1025
-
-
Hoffman, G.E.1
Santilli, B.A.2
Kindig, S.3
Scott, R.T.4
Johnson, C.A.5
-
22
-
-
0018855540
-
-
International Federation of Clinical Chemistry, Scientific Committee, 1980. J. Clin. Chem. Biochem. 18, 521-534.
-
(1980)
J. Clin. Chem. Biochem.
, vol.18
, pp. 521-534
-
-
-
23
-
-
0024122632
-
Stainless steel welding and semen quality
-
Jelnes J.E. Stainless steel welding and semen quality. Reprod. J. Toxicol. 2:1988;209-212.
-
(1988)
Reprod. J. Toxicol.
, vol.2
, pp. 209-212
-
-
Jelnes, J.E.1
-
25
-
-
0026439744
-
Chromosome and sister-chromatid exchange analysis in peripheral lymphocytes, and mutagenicity of urine in anesthesiology personnel
-
Karelova J., Jablonicka A., Gavora J., Hano L. Chromosome and sister-chromatid exchange analysis in peripheral lymphocytes, and mutagenicity of urine in anesthesiology personnel. Int. Arch. Occup. Environ. Health. 64:1992;303-306.
-
(1992)
Int. Arch. Occup. Environ. Health
, vol.64
, pp. 303-306
-
-
Karelova, J.1
Jablonicka, A.2
Gavora, J.3
Hano, L.4
-
26
-
-
0025187326
-
Factors affecting the expression of trifluoroacetylated liver microsomal protein neoantigens in rats treated with halothane
-
Kenna J.G., Martin J.L., Satoh H., Pohl L.R. Factors affecting the expression of trifluoroacetylated liver microsomal protein neoantigens in rats treated with halothane. Drug Metab. Dispos. 18:1990;788-793.
-
(1990)
Drug Metab. Dispos.
, vol.18
, pp. 788-793
-
-
Kenna, J.G.1
Martin, J.L.2
Satoh, H.3
Pohl, L.R.4
-
27
-
-
0017274370
-
Partial structural analysis of the basic protein of rat spermatozoa
-
Kistler W.S., Keim P.S., Heinrikson R.L. Partial structural analysis of the basic protein of rat spermatozoa. Biochem. Biophys. Acta. 427:1976;752-757.
-
(1976)
Biochem. Biophys. Acta
, vol.427
, pp. 752-757
-
-
Kistler, W.S.1
Keim, P.S.2
Heinrikson, R.L.3
-
28
-
-
0014949207
-
Cleavage of structural proteins during the assembly of the head of bacteriophage T4
-
Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 227:1970;680-685.
-
(1970)
Nature
, vol.227
, pp. 680-685
-
-
Laemmli, U.K.1
-
30
-
-
0025025550
-
7-Alkoxyquinolines: New fluorescent substrates for cytochrome P450 monooxygenases
-
Mayer R.T., Netter K.J., Heubel F., Hahnemann B., Buccheister A., Mayer G.K., Burke M.D. 7-Alkoxyquinolines: new fluorescent substrates for cytochrome P450 monooxygenases. Biochem. Pharmacol. 40:1990;1645-1655.
-
(1990)
Biochem. Pharmacol.
, vol.40
, pp. 1645-1655
-
-
Mayer, R.T.1
Netter, K.J.2
Heubel, F.3
Hahnemann, B.4
Buccheister, A.5
Mayer, G.K.6
Burke, M.D.7
-
31
-
-
0033460216
-
Calreticulin: One protein, one gene, many functions
-
Michalak M., Corbett E.F., Mesaeli N., Nakamura K., Opas M. Calreticulin: one protein, one gene, many functions. Biochem. J. 344:1999;281-292.
-
(1999)
Biochem. J.
, vol.344
, pp. 281-292
-
-
Michalak, M.1
Corbett, E.F.2
Mesaeli, N.3
Nakamura, K.4
Opas, M.5
-
32
-
-
4243440845
-
Carboxylesterases moonlight in the male reproductive tract: A functional shift pivotal for male fertility
-
Mikhailov A.T., Torrado M. Carboxylesterases moonlight in the male reproductive tract: a functional shift pivotal for male fertility. Front. Biosci. 5:2000;53-62.
-
(2000)
Front. Biosci.
, vol.5
, pp. 53-62
-
-
Mikhailov, A.T.1
Torrado, M.2
-
33
-
-
0020407548
-
Modification of liver microsomal lipids by halothane metabolites: A multinuclear NMR spectroscopic study
-
Muller R., Srier A. Modification of liver microsomal lipids by halothane metabolites: a multinuclear NMR spectroscopic study. Naunyn Schmiedebergs Arch. Pharmacol. 321:1982;234-237.
-
(1982)
Naunyn Schmiedebergs Arch. Pharmacol.
, vol.321
, pp. 234-237
-
-
Muller, R.1
Srier, A.2
-
34
-
-
0027193903
-
An endoplasmic reticulum protein, calreticulin, is transported into the acrosome of rat sperm
-
Nakamura M., Moriya M., Baba T., Michikawa Y., Yamanobe T., Arai K. An endoplasmic reticulum protein, calreticulin, is transported into the acrosome of rat sperm. Exp. Cell Res. 205:1993;101-110.
-
(1993)
Exp. Cell Res.
, vol.205
, pp. 101-110
-
-
Nakamura, M.1
Moriya, M.2
Baba, T.3
Michikawa, Y.4
Yamanobe, T.5
Arai, K.6
-
36
-
-
0031670441
-
Generation of antibodies to di- and trichloroacetylated proteins and immunochemical detection of protein adducts in rats treated with perchloroethene
-
Pähler A., Birner G., Parker J., Dekant W. Generation of antibodies to di- and trichloroacetylated proteins and immunochemical detection of protein adducts in rats treated with perchloroethene. Chem. Res. Toxicol. 11:1997;995-1004.
-
(1997)
Chem. Res. Toxicol.
, vol.11
, pp. 995-1004
-
-
Pähler, A.1
Birner, G.2
Parker, J.3
Dekant, W.4
-
37
-
-
0026069960
-
Hapten carrier conjugates associated with halothane hepatitis
-
Pohl L.R., Thomassen D., Pumford N.R., Butler L.E., Satoh H., Ferrans V.J., Perrone A., Martin B.M., Martin J.L. Hapten carrier conjugates associated with halothane hepatitis. Adv. Exp. Med. Biol. 283:1991;111-120.
-
(1991)
Adv. Exp. Med. Biol.
, vol.283
, pp. 111-120
-
-
Pohl, L.R.1
Thomassen, D.2
Pumford, N.R.3
Butler, L.E.4
Satoh, H.5
Ferrans, V.J.6
Perrone, A.7
Martin, B.M.8
Martin, J.L.9
-
38
-
-
0034567095
-
Cytochromes P450 involved with benzene metabolism in hepatic and pulmonary microsomes
-
Powley M.W., Carlson G.P. Cytochromes P450 involved with benzene metabolism in hepatic and pulmonary microsomes. J. Biochem. Mol. Toxicol. 14:2000;303-309.
-
(2000)
J. Biochem. Mol. Toxicol.
, vol.14
, pp. 303-309
-
-
Powley, M.W.1
Carlson, G.P.2
-
39
-
-
0027476657
-
Bioactivation of halogenated hydrocarbons by cytochrome P4502E1
-
Raucy J.L., Kraner J.C., Lasker J.M. Bioactivation of halogenated hydrocarbons by cytochrome P4502E1. Crit. Rev. Toxicol. 23:1993;1-20.
-
(1993)
Crit. Rev. Toxicol.
, vol.23
, pp. 1-20
-
-
Raucy, J.L.1
Kraner, J.C.2
Lasker, J.M.3
-
41
-
-
0022117289
-
P-Nitrophenol hydroxylation: A microsomal oxidation which is highly inducible by ethanol
-
Reinke L.A., Moyer M.J. p-Nitrophenol hydroxylation: a microsomal oxidation which is highly inducible by ethanol. Drug Metab. Dispos. 13:1985;548-552.
-
(1985)
Drug Metab. Dispos.
, vol.13
, pp. 548-552
-
-
Reinke, L.A.1
Moyer, M.J.2
-
42
-
-
0009526864
-
Inhalation toxicology
-
D. Anderson, & D.M. Conning. UK: Cambridge Royal Society of Chemistry
-
Riley R.A., Conning D.M. Inhalation toxicology. Anderson D., Conning D.M. Experimental Toxicology: The Basic Issues. 1990;107-118 Cambridge Royal Society of Chemistry, UK.
-
(1990)
Experimental Toxicology: The Basic Issues
, pp. 107-118
-
-
Riley, R.A.1
Conning, D.M.2
-
43
-
-
0021816377
-
Immunological studies on the mechanism of halothane-induced hepatotoxicity: Immunohistochemical evidence of trifluoroacetylated hepatocytes
-
Satoh H., Fukuda Y., Anderson D.K., Ferrans V.J., Gillete J.R., Pohl L.R. Immunological studies on the mechanism of halothane-induced hepatotoxicity: immunohistochemical evidence of trifluoroacetylated hepatocytes. J. Pharmacol. Exp. Ther. 233:1985;857-862.
-
(1985)
J. Pharmacol. Exp. Ther.
, vol.233
, pp. 857-862
-
-
Satoh, H.1
Fukuda, Y.2
Anderson, D.K.3
Ferrans, V.J.4
Gillete, J.R.5
Pohl, L.R.6
-
44
-
-
0242689518
-
Human anti-endoplasmic reticulum antibodies in sera from patients with halothane-induced hepatitis are directed against a trifluoroacetylated carboxylesterase
-
Satoh H., Martin B.M., Schulik A.H., Christ D.D., Kenna J.G., Pohl L.R. Human anti-endoplasmic reticulum antibodies in sera from patients with halothane-induced hepatitis are directed against a trifluoroacetylated carboxylesterase. Proc. Natl. Acad. Sci. USA. 86:1989;322-326.
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 322-326
-
-
Satoh, H.1
Martin, B.M.2
Schulik, A.H.3
Christ, D.D.4
Kenna, J.G.5
Pohl, L.R.6
-
45
-
-
0033846723
-
Activation of cytochrome P450 gene expression in the rat brain by phenobarbital-like inducers
-
Schilter B., Andersen M.R., Acharya C., Omiecinski C.J. Activation of cytochrome P450 gene expression in the rat brain by phenobarbital-like inducers. J. Pharmacol. Exp. Ther. 294:2000;916-922.
-
(2000)
J. Pharmacol. Exp. Ther.
, vol.294
, pp. 916-922
-
-
Schilter, B.1
Andersen, M.R.2
Acharya, C.3
Omiecinski, C.J.4
-
46
-
-
0032714453
-
2+ channel subunit expression and immunolocalization in mouse spermatogenic cells and sperm
-
2+ channel subunit expression and immunolocalization in mouse spermatogenic cells and sperm. FEBS Lett. 462:1999;171-176.
-
(1999)
FEBS Lett.
, vol.462
, pp. 171-176
-
-
Serrano, C.J.1
Trevino, C.L.2
Felix, R.3
Darszon, A.4
-
47
-
-
0018175193
-
A review of the effects of trace concentrations of anaesthetics of performance
-
Smith G., Shirley A.W. A review of the effects of trace concentrations of anaesthetics of performance. Br. J. Anaesth. 50:1978;701-712.
-
(1978)
Br. J. Anaesth.
, vol.50
, pp. 701-712
-
-
Smith, G.1
Shirley, A.W.2
-
49
-
-
0030583589
-
Immunological detection of CYP2E1 in fresh rat lymphocytes and its pretranslational induction by fasting
-
Soh Y., Rhee H.M., Sohn D.H., Song B. Immunological detection of CYP2E1 in fresh rat lymphocytes and its pretranslational induction by fasting. Biochem. Biophys. Res. Commun. 227:1996;541-546.
-
(1996)
Biochem. Biophys. Res. Commun.
, vol.227
, pp. 541-546
-
-
Soh, Y.1
Rhee, H.M.2
Sohn, D.H.3
Song, B.4
-
50
-
-
0022869269
-
Complementary DNA and protein sequences of ethanol-inducible rat and human cytochrome P-450s: Transcriptional and post-transcriptional regulation of the rat enzyme
-
Song B.J., Gelboin H.V., Park S.S., Yang C.S., Gonzalez F.J. Complementary DNA and protein sequences of ethanol-inducible rat and human cytochrome P-450s: transcriptional and post-transcriptional regulation of the rat enzyme. J. Biol. Chem. 261:1986;16689-16697.
-
(1986)
J. Biol. Chem.
, vol.261
, pp. 16689-16697
-
-
Song, B.J.1
Gelboin, H.V.2
Park, S.S.3
Yang, C.S.4
Gonzalez, F.J.5
-
51
-
-
0026569805
-
Cytochromes P-450 in rats: Structures, functions, properties and relevant human forms
-
Soucek P., Gut I. Cytochromes P-450 in rats: structures, functions, properties and relevant human forms. Xenobiotica. 22:1992;83-103.
-
(1992)
Xenobiotica
, vol.22
, pp. 83-103
-
-
Soucek, P.1
Gut, I.2
-
52
-
-
0030924897
-
Cytochrome P450 2E1 is the principal catalyst of human oxidative metabolism in vitro
-
Spracklin D.K., Hankins D.C., Fisher J.M., Thummel K.E., Kharasch E.D. Cytochrome P450 2E1 is the principal catalyst of human oxidative metabolism in vitro. J. Pharmacol. Exp. Ther. 281:1997;400-411.
-
(1997)
J. Pharmacol. Exp. Ther.
, vol.281
, pp. 400-411
-
-
Spracklin, D.K.1
Hankins, D.C.2
Fisher, J.M.3
Thummel, K.E.4
Kharasch, E.D.5
-
53
-
-
0025100726
-
The role of a stress protein in the development of a drug-induced allergic response
-
Thomassen D., Martin B.M., Martin J.L., Pumford N.R., Pohl L.R. The role of a stress protein in the development of a drug-induced allergic response. Eur. J. Pharmacol. 183:1989;1138-1139.
-
(1989)
Eur. J. Pharmacol.
, vol.183
, pp. 1138-1139
-
-
Thomassen, D.1
Martin, B.M.2
Martin, J.L.3
Pumford, N.R.4
Pohl, L.R.5
-
54
-
-
0009482260
-
Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications
-
Towbin H., Staehelin T., Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc. Natl. Acad. Sci. USA. 76:1979;4350-4354.
-
(1979)
Proc. Natl. Acad. Sci. USA
, vol.76
, pp. 4350-4354
-
-
Towbin, H.1
Staehelin, T.2
Gordon, J.3
-
55
-
-
0021855193
-
Subchronic inhalation toxicity of benzene in rats and mice
-
Ward C.O., Kuna R.A., Sydner N.K., Alsaker R.D., Coate W.B., Craig P.H. Subchronic inhalation toxicity of benzene in rats and mice. Am. J. Ind. Med. 7:1985;457-473.
-
(1985)
Am. J. Ind. Med.
, vol.7
, pp. 457-473
-
-
Ward, C.O.1
Kuna, R.A.2
Sydner, N.K.3
Alsaker, R.D.4
Coate, W.B.5
Craig, P.H.6
-
56
-
-
0009462710
-
Inhalation toxicity studies
-
I.G. Sipes, C.A. McQueen, Gandolfi A.J. Cambridge: Cambridge University Press
-
Wolff R.K., Dorato M.A. Inhalation toxicity studies. Sipes I.G., McQueen C.A., Gandolfi A.J. Toxicological Testing and Evaluation: Comprehensive Toxicology. 2:1997;269-289 Cambridge University Press, Cambridge.
-
(1997)
Toxicological Testing and Evaluation: Comprehensive Toxicology
, vol.2
, pp. 269-289
-
-
Wolff, R.K.1
Dorato, M.A.2
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