Synthesis, characterization and preliminary cytotoxicity assays of poly(ethylene glycol)-malonato-Pt-DACH conjugates

European Journal of Medicinal Chemistry

Volumn 38, Issue 7-8, 2003, Pages 739-749

  Furin, Alessia ^a   Guiotto, Andrea ^b   Baccichetti, Franca ^a   Pasut, Gianfranco ^a   Deuschel, Christine ^c   Bertani, Roberta ^a   Veronese, Francesco M ^a  

^a UNIVERSITY OF PADOVA   (Italy)

^b CNR   (Italy)

^c DEBIOPHARM SA   (Switzerland)

Author keywords

Anticancer drug; Oxaliplatin; Platinum; Poly(ethylene glycol); Pt DACH

Indexed keywords

MACROGOL DERIVATIVE; MALONIC ACID DERIVATIVE; OXALIPLATIN; PLATINUM COMPLEX;

ANIMAL EXPERIMENT; ANTINEOPLASTIC ACTIVITY; ARTICLE; CHEMICAL ANALYSIS; CYTOTOXICITY; DRUG SYNTHESIS; ENDOCYTOSIS; ENZYMATIC DEGRADATION; ENZYME SUBSTRATE; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE;

EID: 0042156815     PISSN: 02235234     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0223-5234(03)00114-4     Document Type: Article

References (18)

1. Carter S.K. Hacker M.P., Douple E.B., Krakoff I.H. Platinum Coordination Complexes in Cancer Chemotherapy. 1984;359 Martinus Nijhoff, Boston, MA.
2. Van der Veer J.L., Reedijk J. Chem. Br. 24:1988;775.
3. Krakoff I.H. Nicolini M. Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy: Clinical Applications of Platinum Complexes. 1988;351 Martinus Nijhoff, Boston, MA.
4. Loehrer P.J., Williams S.D. Sr, Einhorn L.H. J. Natl. Cancer Inst. 80:1988;1373.
5. Extra J.M., Espie M., Calvo F., Ferme C., Mignot L., Marty M. Cancer Chemother. Pharmacol. 25:1990;299.
6. Matsumura Y., Maeda H. Cancer Res. 46:1986;6387.
7. Greenwald R.B., Gilbert C.W., Pendri A., Conover C.D., Xia J., Martinez A. J. Med. Chem. 39:1996;424.
8. Vasey P., Twelves C., Kaye S., Wilson P., Morrison R., Duncan R., Thomson A., Hilditch T., Murray T., Burtles S., Cassidy J. Clin. Cancer Res. 5:1999;83.
9. Greenwald R.B., Pendri A., Conover C., Gilbert C., Yang R., Xia J. J. Med. Chem. 39:1996;1938.
10. Choe Y.H., Conover C.D., Wu D.C., Royzen M., Greenwald R.B. J. Controlled Release. 79:2002;41.
11. Gianasi E., Wasil M., Evagorou E.G., Keddle A., Wilson G., Duncan R. Eur. J. Cancer. 35:1999;994-1002.
12. Kopecek J., Duncan R. J. Controlled Release. 6:1987;315.
13. Gibson D., Rosenfeld A., Apfelbaum H., Blum J. J. Inorg. Chem. 29:1990;5125.
14. Appleton T.G., Hall J.R., Neale D.W., Thompson S.M. J. Inorg. Chem. 29:1990;3985.
15. Sims G.E., Snape T.J. Anal. Biochem. 107:1980;60.
16. Talebian A.H., Bensely D., Schein P.S., Green D. Anti-Cancer Drug Des. 5:1990;371.
17. Gianasi E., Buckley R.G., Latigo J., Wasil M., Duncan R. J. Drug Targeting. 10:2002;549.
18. Yamaoka T., Tabata Y., Ikada Y. J. Pharm. Sci. 83:1994;601.