It's only teeth - Are there limits to genetic testing?

Clinical Genetics

Volumn 63, Issue 5, 2003, Pages 333-339

  Aldred, Michael J ^a,b,c   Crawford, P J M ^d   Savarirayan, R ^a,b,c   Savulescu, J ^b,c  

^a ROYAL CHILDREN'S HOSPITAL   (Australia)

^b MURDOCH CHILDREN'S RESEARCH INSTITUTE   (Australia)

^c UNIVERSITY OF MELBOURNE   (Australia)

^d UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

Amelogenesis imperfecta; Dentinogenesis imperfecta; Ethics; Genetic counselling; Genetic testing; Hypodontia

Indexed keywords

AMELOGENESIS IMPERFECTA; AWARENESS; FAMILY COUNSELING; FAMILY LIFE; FERTILIZATION IN VITRO; FINANCIAL MANAGEMENT; GENE THERAPY; GENETIC COUNSELING; GENETIC DISORDER; GENETIC RISK; GENETIC SCREENING; HEALTH CARE COST; HUMAN; HYPODONTIA; MEDICAL ETHICS; MOLECULAR GENETICS; PREGNANCY TERMINATION; PRENATAL DIAGNOSIS; PRIORITY JOURNAL; PSYCHOLOGICAL ASPECT; REPRODUCTION; REVIEW; SOCIAL ASPECT; TOOTH DISEASE; TOOTH MALFORMATION;

GENETICS AND REPRODUCTION;

AMELOGENESIS IMPERFECTA; ANODONTIA; DENTINOGENESIS IMPERFECTA; FEMALE; GENE THERAPY; GENETIC COUNSELING; GENETIC PREDISPOSITION TO DISEASE; GENETIC SCREENING; HUMANS; MALE; MASS SCREENING; PRENATAL DIAGNOSIS; TOOTH DISEASES;

EID: 0042131874     PISSN: 00099163     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1399-0004.2003.00045.x     Document Type: Review

References (13)

1. Online Mendelian Inheritance in Man, OMIM (TM). Johns Hopkins University, Baltimore, MD. MIM Number: 305100: 16 August 2002. World Wide Web URL: http:// www.ncbi.nlm.nih.gov/omim/
2. Online Mendelian Inheritance in Man, OMIM (TM). Johns Hopkins University, Baltimore, MD. MIM Number: 301200: 30 April 2002. World Wide Web URL: http:// www.ncbi.nlm.nih.gov/omim/
3. Online Mendelian Inheritance in Man, OMIM (TM). Johns Hopkins University, Baltimore, MD. MIM Number: 104500: 16 December 2002. World Wide Web URL: http:// www.ncbi.nlm.nih.gov/omim/
4. Online Mendelian Inheritance in Man, OMIM (TM). Johns Hopkins University, Baltimore, MD. MIM Number: 190320: 7 September 1999. World Wide Web URL: http:// www.ncbi.nlm.nih.gov/omim/
5. Xiao S, Yu C, Chou X et al. Dentinogenesis imperfecta 1 with or without progressive hearing loss is associated with distinct mutations in DSPP. Nat Genet 2001: 27: 201-204.
6. Zhang X, Zhao J, Li C et al. DSPP mutation in dentinogenesis imperfecta Shields type II. Nat Genet 2001: 27: 151-152.
7. Vastardis H, Karimbux N, Guthua SW, Seidman JG, Seidman CE. A human MSX1 homeodomain missense mutation causes selective tooth agenesis. Nat Genet 1996: 13: 417-421.
8. Stockton DW, Das P, Goldenberg M, D'Souza RN, Patel PI. Mutation of PAX9 is associated with oligodontia. Nat Genet 2000: 24: 18-19.
9. Aspinall CL. Dealing with the prenatal diagnosis of clefting: a parent's perspective. Cleft Palate Craniofac J 2002: 39: 183-187.
10. Strauss RP. Beyond easy answers: prenatal diagnosis and counseling during pregnancy. Cleft Palate Craniofac J 2002: 39: 164-168.
11. Topping A, Harris P, Moss AL. The 6p deletion syndrome: a new orofacial clefting syndrome and its implications for antenatal screening. Br J Plast Surg 2002: 55: 68-72.
12. Savulescu J. Is current practice around late termination of pregnancy eugenic and discriminatory? J Med Ethics 2001: 27: 165-171.
13. Savulescu J. Procreative beneficence: why we should select the best children. Bioethics 2001: 15: 413-426.