The 6p deletion syndrome: A new orofacial clefting syndrome and its implications for antenatal screening

British Journal of Plastic Surgery

Volumn 55, Issue 1, 2002, Pages 68-72

  Topping, Adam ^a   Harris, Paul ^a   Moss, Tony ^a  

^a ST GEORGE'S UNIVERSITY HOSPITALS NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

6p deletion syndrome; Ethics; Orofacial clefting; Screening

Indexed keywords

ARTICLE; CASE REPORT; CHROMOSOME 6P; CHROMOSOME ABERRATION; CHROMOSOME DELETION; CLEFT LIP FACE PALATE; EAR MALFORMATION; FEMALE; GENETIC DISORDER; GENETIC SCREENING; GENETIC TRAIT; HUMAN; HYPERTELORISM; MALFORMATION SYNDROME; MEDICAL ETHICS; METHODOLOGY; NEWBORN; PALPEBRAL FISSURE ANOMALY; PRENATAL DIAGNOSIS; PRIORITY JOURNAL; PUBLISHING; SIBLING; UNITED KINGDOM;

EID: 0036149070     PISSN: 00071226     EISSN: None     Source Type: Journal    
DOI: 10.1054/bjps.2001.3729     Document Type: Article

References (24)

1. Suggestion of linkage of a major locus for nonsyndromic orofacial cleft with F13A and tentative assignment to chromosome 6
2. 1q32-q41 microdeletion with reference to Van der Woude syndrome and allied clefting entities
3. A case of partial monosomy 6p
4. Partial deletion of chromosome 6p: Delineation of the syndrome
5. Distal 6p deletion syndrome: A report of a case with anterior chamber eye anomaly and review of published reports
6. Further evidence for the involvement of human chromosome 6p24 in the aetiology of orofacial clefting
7. Evidence of a locus for orofacial clefting on human chromosome 6p24 and STS content map of the region
8. A patient with an interstitial deletion of the short arm of chromosome 6
9. Tandem Y/6 translocation with partial deletion 6 (p23--pter)
10. Terminal deletion 6p23: A case report
11. Clinical evidence for localisation of HLA proximal of chromosome 6p22
12. A detailed investigation of two cases exhibiting characteristics of the 6p deletion syndrome
13. Distal deletion of the short arm of chromosome 6
14. Two rare cases of 6p partial deletion
15. Evidence for an association between markers on chromosome 19q and non-syndromic cleft lip with or without cleft palate in two groups of multiplex families
16. Evidence of linkage to 6p23 and genetic heterogeneity in non-syndromic cleft lip with or without cleft palate
17. Parental decisions regarding termination of pregnancy following prenatal detection of sex chromosome abnormality
18. Prenatal diagnosis using fetal cells from the maternal circulation
19. Reproductive genetics and today's patient options: Pre-natal diagnosis
20. First trimester maternal serum concentrations of fetal antigen 2 in normal pregnancies and those affected by trisomy 21