Antisense oligonucleotide against 47-kDa heat shock protein (Hsp47) inhibits wound-induced enhancement of collagen production

Archives of Oral Biology

Volumn 48, Issue 9, 2003, Pages 627-633

  Ohba, S ^a   Wang, Z L ^a   Baba, T T ^a   Nemoto, T K ^a   Inokuchi, T ^a  

^a NAGASAKI UNIVERSITY   (Japan)

Author keywords

Antisense; Collagen; Fibroblast; Hsp47; Scar formation; Wound healing

Indexed keywords

EID: 0042125387     PISSN: 00039969     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0003-9969(03)00117-1     Document Type: Article

References (29)

1. Bleacher JC, Adolph VR, Dillon PW, Krummel TM. Fetal tissue repair and wound healing. Dermatol Clin 1993;11: 677-83.
2. Diegelmann RF, Cohen IK, Kaplan AM. The role of macrophages in wound repair: a review. Plast Reconstr Surg 1981; 68:107-13.
3. Leibovich SJ, Ross R. The role of the macrophage in wound repair. A study with hydrocortisone and antimacrophage serum. Am J Pathol 1975;78:71-100.
4. Saga S, Hamaguchi M, Hoshino M, Kojima K. Expression of meta-vinculin associated with differentiation of chicken embryonal muscle cells. Exp Cell Res 1985;156:45-56.
5. Nagata K. Hsp47: a collagen-specific molecular chaperone. Trends Biochem Sci 1996;21:22-6.
6. Nagata K. Expression and function of heat shock protein 47: a collagen-specific molecular chaperone in the endoplasmic reticulum. Matrix Biol 1998;16:379-86.
7. Nakai A, Satoh M, Hirayoshi K, Nagata K. Involvement of the stress protein HSP47 in procollagen processing in the endoplasmic reticulum. J Cell Biol 1992;117:903-14.
8. Kuroda K, Tsukifuji R, Shinkai H. Increased expression of heat-shock protein 47 is associated with overproduction of type I procollagen in systemic sclerosis skin fibroblasts. J Invest Dermatol 1998;111:1023-8.
9. Lamande SR, Bateman JF. Procollagen folding and assembly: the role of endoplasmic reticulum enzymes and molecular chaperones. Semin Cell Dev Biol 1999;10:455-64.
10. Tomita M, Yoshizato K, Nagata K, Kitajima T. Enhancement of secretion of human procollagen I in mouse HSP47-expressing insect cells. J Biochem Tokyo 1999;126:1118-26.
11. Nagai N, Hosokawa M, Itohara S, et al. Embryonic lethality of molecular chaperone hsp47 knockout mice is associated with defects in collagen biosynthesis. J Cell Biol 2000;150: 1499-506.
12. Dafforn TR, Della M, Miller AD. The molecular interactions of heat shock protein 47 (Hsp47) and their implications for collagen biosynthesis. J Biol Chem 2001;276:49310-9.
13. Siebert JW, Burd AR, McCarthy JG, Weinzweig J, Ehrlich HP. Fetal wound heating: a biochemical study of scarless healing. Plast Reconstr Surg 1990;85:495-504.
14. Lorenz HP, Adzick NS. Scarless skin wound repair in the fetus. West J Med 1993;159:350-5.
15. Nodder S, Martin P. Wound healing in embryos: a review. Anat Embryol (Berl) 1997;195:215-28.
16. Wang ZL, Inokuchi T, Ikeda H, et al. Collagen-binding heat shock protein HSP47 expression during healing of fetal skin wounds. Int J Oral Maxillofac Surg 2002;31:179-84.
17. Ohba S, Baba TT, Nemoto TK, Inokuchi T. Expression of Hsp47 in fibroblasts derived from fetal and neonatal rat tongues. Jpn J Oral Biol 2002;44:541-8.
18. Wang ZL, Inokuchi T, Nemoto TK, Uehara M, Baba TT. Antisense oligonucleotide against collagen-specific molecular chaperone HSP47 suppresses scar formation in rat wound. Plast Reconstr Surg 2003;111:1980-7.
19. Sauk JJ, Smith T, Norris K, Ferreira L. Hsp47 and the translocation machinery cooperate in the production of alpha 1(I) chains of type I procollagen. J Biol Chem 1994; 269:3941-6.
20. Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970; 227:680-5.
21. Seth A, Lee BK, Qi S, Vary CP. Coordinate expression of novel genes during osteobtast differentiation. J Bone Miner Res 2000;15:1683-96.
22. Masuda H, Fukumoto M, Hirayoshi K, Nagata K. Coexpression of the collagen-binding stress protein HSP47 gene and the α1(I) and α1(III) collagen genes in carbon tetrachloride-induced rat liver fibrosis. J Clin Invest 1994;94:2481-8.
23. Wang JF, Olson ME, Reno CR, Kulyk W, Wright JB, Hart DA. Molecular and cell biology of skin wound healing in a pig model. Connect Tissue Res 2000;41:195-211.
24. Sunamoto M, Kuze K, Tsuji H, et al. Antisense oligonucleotides against collagen-binding stress protein HSP47 suppress collagen accumulation in experimental glomeruloneophritis. Lab Invest 1998;78:967-72.
25. Kubo H. Expression and Localization of basic fibroblast growth factor in incisional tongue wounds of glucocorticoid-treated rats. Shika Igaku (J Osaka Odontol Soc) 1997;60: 241-55 [in Japanese].
26. Clarke EP, Cates GA, Ball EH, Sanwal BD. A collagen-binding protein in the endoplasmic reticulum of myofibroblasts exhibits relationship with serine protease inhibitors: rat heat-shock collagen-binding protein (gp46). J Biol Chem 1991;266:17230-5.
27. Waggett AD, Ralphs JR, Kwan AP, Woodnutt D, Benjamin M. Characterization of collagens and proteoglycans at the insertion of the human Achilles tendon. Matrix Biol 1998; 16:457-70.
28. Lovaud S, Poirier B, Mandet C, Belair MF, Iriopoulou T, Heudes D, et al. Inflammation is probably not a prerequisite for renal interstitial fibrosis in normoglycemic obese rats. Am J Physiol Renal Physiol 2001;280:F683-94.
29. Ando T, Okuda S, Tamaki K, Yoshitomi K, Fujishima M. Localization of transforming growth factor-beta and latent transforming growth factor-beta binding protein in rat kidney. Kidney Int 1995;47:733-9.