Protective effect of quercetin on renal ischemia/reperfusion injury in rats

Journal of Nephrology

Volumn 16, Issue 2, 2003, Pages 219-224

  Kahraman, Ahmet ^a   Erkasap, Nilüfer ^b   Serteser, Mustafa ^a   Köken, Tülay ^a  

^a AFYON KOCATEPE UNIVERSITY   (Turkey)

^b ESKISEHIR OSMANGAZI UNIVERSITY   (Turkey)

Author keywords

Ischemia reperfusion; Oxidative stress; Quercetin

Indexed keywords

CARBONYL DERIVATIVE; CATALASE; DRUG VEHICLE; ENZYME; GLUTATHIONE; MYELOPEROXIDASE; PROTEIN; QUERCETIN; SCAVENGER; SODIUM CHLORIDE; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID; THIOPENTAL; TUMOR NECROSIS FACTOR ALPHA; GLUTATHIONE PEROXIDASE; MALONALDEHYDE; PROTECTIVE AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; KIDNEY INJURY; KIDNEY ISCHEMIA; KIDNEY PARENCHYMA; NONHUMAN; RAT; REPERFUSION INJURY; ANIMAL; COMPARATIVE STUDY; DISEASE MODEL; FEMALE; ISCHEMIA; KIDNEY DISEASE; MALE; NEPHRECTOMY; OXIDATIVE STRESS; PATHOLOGY; PATHOPHYSIOLOGY; PROBABILITY; REFERENCE VALUE; SENSITIVITY AND SPECIFICITY; SPRAGUE DAWLEY RAT;

ANIMALS; DISEASE MODELS, ANIMAL; FEMALE; GLUTATHIONE PEROXIDASE; ISCHEMIA; KIDNEY DISEASES; MALE; MALONDIALDEHYDE; NEPHRECTOMY; OXIDATIVE STRESS; PROBABILITY; PROTECTIVE AGENTS; QUERCETIN; RATS; RATS, SPRAGUE-DAWLEY; REFERENCE VALUES; REPERFUSION INJURY; SENSITIVITY AND SPECIFICITY; SUPEROXIDE DISMUTASE;

EID: 0042020222     PISSN: 11218428     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (32)

1. Kelly KJ, Jr. Williams WW, Colvin RB, Meehan SM, Springer TA, Gutierrez-Ramos J-C, Bonventre JV. Intercellular adhesion molecule-1-deficient mice are protected against ischemic renal injury. J Clin Invest 1996; 97: 1056-63.
2. Granger DN, Korthuis RJ. Physiologic mechanisms of postischemic tissue injury. Annu Rev Physiol 1995; 57: 312-32.
3. Hauet T, Michel G, Vandewalle A. To what extent can limiting cold ischemia/reperfusion injury prevent delayed graft function? Nephrol Dial Transplant 2001; 16: 1982-5.
4. Stadtman ER, Berlett BS. Free-radical-mediated modification of proteins. In Wallace KB, ed. Free Radical Toxicology. Taylor&Francis, 1997; 71-87.
5. Singbartl K, Ley K. Protection from ischemia-reperfusion induced severe acute renal failure by blocking E-selectin. Crit Care Med 2000; 28: 2507-14.
6. Heinzelmann M, Mercer-Jones MA, Passmore J. Neutrophils and renal failure. Am J Kidney Dis 1999; 34: 384-9.
7. Jaeschke H, Mitchell JR. Use of isolated perfused organs in hypoxia and ischemia/reperfusion oxidant stress. Methods Enzymol 1990; 186: 752-9.
8. Szeto YT, Benzie IFF. Effects of dietary antioxidants on human DNA ex vivo. Free Radic Res 2002; 36: 113-8.
9. Inal ME, Kahraman A. The protective effect of flavonol quercetin against ultraviolet A induced oxidative stress in rats. Toxicology 2000; 154: 21-9.
10. Formica JV, Regelson W. Review of the biology of quercetin and related bioflavonoids. Food Chem Toxicol 1995; 33: 1061-80.
11. Robak J, Gryglewski RJ. Flavonoids are scavengers of superoxide anions. Biochem Pharmacol 1988; 37: 837-41.
12. Terao J, Piskula M, Yao Q. Protective effect of epicatechin, epicatechin gallate and quercetin on lipid peroxidation in phospholipid bilayers. Arch Biochem Biophys 1994; 308: 278-84.
13. Ohkawa H, Ohishi N, Yagi K. Assay for lipid peroxidase in animal tissues by thiobarbituric acid reaction. Anal Biochem 1979; 95: 351-8.
14. Levine RL, Garland D, Oliver CN, Amici A, Climent I, Lenz A, Ahn BW, Shaltiel S, Stadman ER. Determination of carbonyl content in oxidatively modified proteins. Methods Enzymol 1990; 186: 464-78.
15. Beutler E, Robson MJ, Buttenwieser E. The glutathione instability of drug-sensititive red cells. J Lab Clin Med 1957; 49: 84-95.
16. Beutler E, ed. Red Cell Metabolism, a Manual of Biochemical Methods. New York: Grune & Stratton, Inc 1973; 76-85.
17. Winterbourn CC, Hawkins RE, Brian M, Correll RW. The estimation of red cell superoxide dismutase activity. J Lab Clin Med 1957; 49: 84-95.
18. Suzuki K, Ota H, Sasagawa S, Sakatani T, Fujikura T. Assay method for myloperoxidase in human polymorphonuclear leukocytes. Anal Biochem 1983; 132: 345-52.
19. Donnahoo KK, Meng X, Ayala A, Cain MP, Harken AH, Meldrum DR. Early kidney TNF-α expression mediates neutrophil infiltration and injury after renal ischemia-reperfusion. Am J Physiol 1999; 46: R922-9.
20. Husain SR, Cillard J, Cillard P. Hydroxyl radical scavenging activity of flavonoids. Phytochemistry 1987; 26: 2489-91.
21. Bors W, Heller W, Michel C, Saran M. Flavonoid as antioxidants: Determination of radical-scavenging efficiencies. Methods Enzymol 1990; 186: 143-55.
22. Jones EA, Shoskes DA. The effect of mycophenolate mofetil and polyphenolic bioflavanoids on renal ischemia reperfusion injury and repair. J Urol 2000; 163: 999-1004.
23. Shoskes DA. Effect of quercetin and curcumin on ischemic renal injury: A new class of renoprotective agents. Transplantation 1998; 66: 147-52.
24. Sanhueza J, Valdes J, Campos R, Garido A, Valezuela A. Changes in the xanthine dehydrogenase/xanthine oxidase ratio in the rat kidney subjected to ischemia-reperfusion stress: Preventative affect of some flavonoids. Res Commun Chem Pathol Pharmacol 1992; 78: 211-8.
25. Nagao A, Seki M, Kobayashi H. Inhibition of xanthine oxidase by flavonoids. Biosci Biotechnol Biochem 1999; 63: 1787-90.
26. Inal ME, Kahraman A, Koken T. Beneficial effects of quercetin on oxidative stress induced by ultraviolet A. Clin Exp Dermatol 2001; 26: 536-9.
27. Dobashi K, Ghosh B, Orak JK, Singh I, Singh AK. Kidney ischemia-reperfusion: Modulation of antioxidant defenses. Mol Cell Biochem 2000; 205: 1-11.
28. Yüceyar S, Gümüştaş K, Erturk S, Hamzaoǧlu IH, Uygun N, Ayaz M, Cengiz A, Kafadar Y. The role of oxygen free radicals in acute renal failure complicating obstructive jaundice: An experimental study. HPB Surg 1998; 10: 378-93.
29. Colletti LM, Remick DG, Burtch GD, Kunkel SL, Sterieter RM, Campbell DA Jr. Role of tumor necrosis factor-α in the pathologic alterations after hepatic ischemia-reperfusion injury in the rat. J Clin Invest 1990; 85: 1936-43.
30. Ysebaert DK, De Greef KE, Vercauteren SR, Ghielli M, Verpooten GA, Eyskens EJ, De Broe ME. Identification and kinetics of leukocytes after severe ischemia/reperfusion renal injury. Nephrol Dial Transplant 2000; 15: 1562-74.
31. Tsuruma T, Yagihashi A, Watanabe N, Yajima T, Kameshima H, Araya J, Hirata K. Heat-shock protein-73 protects against small intestinal warm ischemia-reperfusion injury in the rat. Surgery 1999; 125: 385-95.
32. Stavric B. Quercetin in our diet: From potent mutagen to probable anticarcinogen. Clin Biochem 1994; 27: 245-8.