The effect of mycophenolate mofetil and polyphenolic bioflavonoids on renal ischemia reperfusion injury and repair

Journal of Urology

Volumn 163, Issue 3, 2000, Pages 999-1004

  Jones, Eric A ^a   Shoskeses, Daniel A ^a  

^a HARBOR UCLA MEDICAL CENTER   (United States)

Author keywords

Curcumin; Kidney; Mycophenolic acid; Quercetin; Reperfusion injury

Indexed keywords

BIOFLAVONOID; CURCUMIN; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; QUERCETIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CREATININE BLOOD LEVEL; GRAFT REJECTION; GRAFT SURVIVAL; IMMUNE RESPONSE; IMMUNOHISTOCHEMISTRY; IMMUNOSUPPRESSIVE TREATMENT; KIDNEY DISEASE; KIDNEY ISCHEMIA; MALE; NONHUMAN; POSTOPERATIVE COMPLICATION; PRIORITY JOURNAL; RAT; REPERFUSION INJURY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SKIN ALLOGRAFT; TISSUE REPAIR;

EID: 0033953935     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-5347(05)67871-8     Document Type: Article

References (39)

1. Shoskes, D. A. and Halloran, P. F.: Delayed graft function in renal transplantation: etiology, management and long-term significance. J Urol, 155: 1831, 1996
2. Shoskes, D. A., Parfrey, N. A. and Halloran, P. F.: Increased major histocompatibility complex antigen expression in unilateral ischemic acute tubular necrosis in the mouse. Transplantation, 49: 201, 1990
3. Rice-Evans, C. A., Miller, N. J. and Paganga, G.: Structure-antioxidant activity relationships of flavonoids and phenolic acids. Free Radic Biol Med, 20: 933, 1996
4. Shoskes, D.: Effect of bioflavonoids quercetin and curcumin on ischemic renal injury. Transplantation, 66: 147, 1998
5. Gavrieli, Y., Sherman, Y. and Ben-Sasson, S. A.: Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell Biol, 119: 493, 1992
6. Ellwart, E. and Dormer, P.: Effect of 5-Flouro-2′-Deoxyuridine (FdUrd) on 5-Bromo-2′-Deoxyuridine (BrdUrd) incorporation into DNA measured with monoclonal BrdUrd antibody and by the BrdUrd/Hoechst quenching effect. Cytometry, 6: 513, 1985
7. Chomcynzki, P. and Sacchi, N.: Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem, 162: 156, 1987
8. Nadeau, K. C., Azua, H. and Tilney, N. L.: Sequential cytokine dynamics in chronic rejection of rat renal allografts: roles for cytokines RANTES and MCP-1. Proc Natl Acad Sci USA, 92: 8729, 1995
9. Utans, U., Quist, W. C., McManus, B. M., Wilson, J. E., Arceci, R. J., Wallace, A. F. and Russell, M. E.: Allograft inflammatory factor-1. A cytokine-responsive macrophage molecule expressed in transplanted human hearts. Transplantation, 61: 1387, 1996
10. Almond, P. S., Matas, A., Gillingham, K., Dunn, D. L., Payne, W. D., Gores, P., Gruessner, R. and Najarian, J. S.: Risk factors for chronic rejection in renal allograft recipients. Transplantation, 55: 752, 1993
11. Satyanarayana, K. and Shoskes, D. A.: A molecular injury-response model for the understanding of chronic disease. Mol Med Today, 3: 331, 1997
12. Sreejayan, N. and Rao, M. N.: Curcuminoids as potent inhibitors of lipid peroxidation. J Pharm Pharmacol, 46: 1013, 1994
13. Singhal, R. L., Yeh, Y. A., Praja, N., Olah, E., Sledge, G. W. Jr., and Weber, G.: Quercetin down-regulates signal transduction in human breast carcinoma cells. Biochem Biophys Res Commun, 208: 425, 1995
14. Babu, P. S. and Srinivasan, K.: Hypolipidemic action of curcumin, the active principle of turmeric (Curcuma longa) in streptozotocin induced diabetic rats. Mol Cell Biochem, 166: 169, 1997
15. Huang, H. C., Jan, T. R. and Yeh, S. F.: Inhibitory effect of curcumin, an anti-inflammatory agent, on vascular smooth muscle cell proliferation. Eur J Pharmacol, 221: 381, 1992
16. Namgoong, S. Y., Son, K. H., Chang, H. W., Kang, S. S. and Kim, H. P.: Effects of naturally occurring flavonoids on mitogen-induced lymphocyte proliferation and mixed lymphocyte culture. Life Sci, 54: 313, 1994
17. Knekt, P., Jarvinen, R. and Reunanen, A. and Maatela, J.: Flavonoid intake and coronary mortality in Finland: a cohort study. BMJ 312: 478, 1996
18. Shoskes, D. A., Jones, E. A. and Shahed, A.: Synergy of mycophenolate mofetil and bioflavonoids in prevention of immune and ischemic injury. Transplant Proc (in press)
19. Franklin, T. J. and Cook, J. M.: The inhibition of nucleic acid synthesis by mycophenolic acid. Biochem J, 113: 515, 1969
20. Zeevi, A., Yao, G. Z., Venkataramanan, R., Duquesnoy, R. J., Todo, S., Fung, J. J. and Starzl, T. E.: Comparative in vitro studies on the immunosupressive effects of purine and pyrimidine synthesis inhibitors. Transplant Proc, 25: 781, 1993
21. Olsen, S., Burdick, J. F., Keown, P. A., Wallace, A. C., Racusen, L. C. and Solez, K.: Primary acute renal failure ("acute tubular necrosis") in the transplanted kidney: morphology and pathogenesis. Medicine, 68: 173, 1989
22. Granger, D. N.: Role of xanthine oxidase and granulocytes in ischemia-reperfusion injury. Am J Physiol, 255(6 Pt 2): H1269, 1988
23. Ferrali, M., Signorini, C., Caciotti, B., Sugherini, L., Ciccoli, L., Giachetti, D. and Comporti, M.: Protection against oxidative damage of erythrocyte membrane by the flavonoid quercetin and its relation to iron chelating activity. FEBS Lett, 416: 123, 1997
24. Hanasaki, Y., Ogawa, S. and Fukui, S.: The correlation between active oxygen scavenging and antioxidative effects of flavonoids. Free Radic Biol Med, 16: 845, 1994
25. Soudamini, K. K., Unnikrishnan, M. C., Soni, K. B. and Kuttan, R.: Inhibition of lipid peroxidation and cholesterol levels in mice by curcumin. Indian J Physiol Pharmacol, 36: 239, 1992
26. Hagar, H., Ueda, N. and Shah, S. V.: Tyrosine phosphorylation in DNA damage and cell death in hypoxic injury to LLC-PK1 cells. Kidney Int, 51: 1747, 1997
27. Brouet, I. and Ohshima, H.: Curcumin, an anti-tumor promoter and anti-inflammatory agent, inhibits induction of nitric oxide synthase in activated macrophages. Biochem Biophys Res Commun, 206: 533, 1995
28. Liu, P., Hock, C. E., Nagele, R. and Wong, P. Y.: Formation of nitric oxide, superoxide, and peroxynitrite in myocardial ischemia-reperfusion injury in rats. Am J Physiol, 272(5 Pt 2): H2327, 1997
29. MacMillan-Crow, L. A., Crow, J. P., Kerby, J. D., Beckman, J. S. and Thompson, J. A.: Nitration and inactivation of manganese superoxide dismutase in chronic rejection of human renal allografts. Proc Natl Acad Sci USA, 93: 1853, 1996
30. Gobe, G. C., Axelsen, R. A. and Searle, J. W.: Cellular events in experimental unilateral ischemic renal atrophy and in regeneration after contralateral nephrectomy. Lab Invest, 63: 770, 1990
31. Chang, D. J., Ringold, G. M. and Heller, R. A.: Cell killing and induction of manganese superoxide dismutase by tumor necrosis factor-alpha is mediated by lipoxygenase metabolites of arachidonic acid. Biochem Biophys Res Commun, 188: 538, 1992
32. Hirose, K., Longo, D. L., Oppenheim, J. J. and Matsushima, K.: Overexpression of mitochondrial manganese superoxide dismutase promotes the survival of tumor cells exposed to interleukin-1, tumor necrosis factor, selected anticancer drugs, and ionizing radiation. FASEB J, 7: 361, 1993
33. Luster, A. D.: Chemokines - chemotactic cytokines that mediate inflammation. New Engl J Med, 338: 436, 1998
34. Pattison, J., Nelson, P. J., Huie, P., von Leuttichau, I., Farshid, G., Sibley, R. K. and Krensky, A. M.: RANTES chemokine expression in cell-mediated transplant rejection of the kidney. Lancet, 343: 209, 1994
35. Kondo, T., Novick, A. C., Toma, H. and Fairchild, R. L.: Induction of chemokine gene expression during allogeneic skin graft rejection. Transplantation, 61: 1750, 1996
36. Utans, U., Quist, W. C., McManus, B. M., Wilson, J. E., Arceci, R. J., Wallace, A. F. and Russell, M. E.: Allograft inflammatory factor-1. A cytokine-responsive macrophage molecule expressed in transplanted human hearts. Transplantation, 61: 1387, 1996
37. Autieri, M. V.: cDNA cloning of human allograft inflammatory factor-1: tissue distribution, cytokine induction, and mRNA expression in injured rat carotid arteries. Biochem Biophys Res Commun, 228: 29, 1996
38. Xu, Y. X., Pindolia, K. R., Janakiraman, N., Noth, C. J., Chapman, R. A. and Gautam, S. C.: Curcumin, a compound with anti- inflammatory and anti-oxidant properties, down-regulates chemokine expression in bone marrow stromal cells. Exp Hematol, 25: 413, 1997
39. Singh, S. and Aggarwal, B. B.: Activation of transcription factor NF-kappa B is suppressed by curcumin (diferulolylmethane). J Biol Chem, 270: 2495, 1995