메뉴 건너뛰기




Volumn 27, Issue 4, 2003, Pages 343-350

The multiple negative randomized controlled trials in perinatology - Why?

Author keywords

[No Author keywords available]

Indexed keywords

DEXAMETHASONE; ERYTHROPOIETIN; IMMUNOGLOBULIN; INDOMETACIN; PHENOBARBITAL; RETINOL; XIPAMIDE;

EID: 0041917674     PISSN: 01460005     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0146-0005(03)00042-9     Document Type: Article
Times cited : (11)

References (44)
  • 2
    • 0002922236 scopus 로고
    • Assessing evidence concerning treatment and prevention of diseases of the newborn
    • Sinclair J, Bracken M (eds), Oxford University Press
    • Sinclair J: Assessing evidence concerning treatment and prevention of diseases of the newborn, in Sinclair J, Bracken M (eds): Assessing Evidence Concerning Treatment and Prevention of Diseases of the Newborn Oxford, Oxford University Press, 1992, pp 3-12
    • (1992) Assessing Evidence Concerning Treatment and Prevention of Diseases of the Newborn Oxford , pp. 3-12
    • Sinclair, J.1
  • 3
    • 0035843256 scopus 로고    scopus 로고
    • Adverse effects of early dexamethasone in extremely-low-birth-weight infants
    • National Institute of Child Health and Human Development Neonatal Research Network
    • Stark AR, Carlo WA, Tyson JE, Papile LA, et al: Adverse effects of early dexamethasone in extremely-low-birth-weight infants. National Institute of Child Health and Human Development Neonatal Research Network. N Engl J Med 344:95-101, 2001
    • (2001) N Engl J Med , vol.344 , pp. 95-101
    • Stark, A.R.1    Carlo, W.A.2    Tyson, J.E.3    Papile, L.A.4
  • 4
    • 0036735582 scopus 로고    scopus 로고
    • Minimal ventilation to prevent bronchopulmonary dysplasia in extremely-low-birth-weight infants
    • Carlo WA, Stark AR, Wright LL, et al: Minimal ventilation to prevent bronchopulmonary dysplasia in extremely-low-birth-weight infants. J Pediatr 141:370-374, 2002
    • (2002) J Pediatr , vol.141 , pp. 370-374
    • Carlo, W.A.1    Stark, A.R.2    Wright, L.L.3
  • 5
    • 0024587698 scopus 로고
    • High-frequency oscillatory ventilation compared with conventional mechanical ventilation in the treatment of respiratory failure in preterm infants
    • Group HS: High-frequency oscillatory ventilation compared with conventional mechanical ventilation in the treatment of respiratory failure in preterm infants. N Engl J Med 320:88-93, 1989
    • (1989) N Engl J Med , vol.320 , pp. 88-93
    • Group, H.S.1
  • 6
    • 0033017219 scopus 로고    scopus 로고
    • A prospective randomized comparison of conventional mechanical ventilation and very early high frequency oscillatory ventilation in extremely premature newborns with respiratory distress syndrome
    • Plavka R, Kopecky P, Sebron V, et al: A prospective randomized comparison of conventional mechanical ventilation and very early high frequency oscillatory ventilation in extremely premature newborns with respiratory distress syndrome. Intens Care Med 25:68-75, 1999
    • (1999) Intens Care Med , vol.25 , pp. 68-75
    • Plavka, R.1    Kopecky, P.2    Sebron, V.3
  • 7
    • 0026580306 scopus 로고
    • Prospective randomized comparison of high-frequency oscillatory and conventional ventilation in respiratory distress syndrome
    • Clark RH, Gerstmann DR, Null DM, Jr, et al: Prospective randomized comparison of high-frequency oscillatory and conventional ventilation in respiratory distress syndrome. Pediatrics 89:5-12, 1992
    • (1992) Pediatrics , vol.89 , pp. 5-12
    • Clark, R.H.1    Gerstmann, D.R.2    Null D.M., Jr.3
  • 8
    • 0027509646 scopus 로고
    • Randomized study of high-frequency oscillatory ventilation in infants with severe respiratory distress syndrome
    • Group HS: Randomized study of high-frequency oscillatory ventilation in infants with severe respiratory distress syndrome. J Pediatr 122:609-619, 1993
    • (1993) J Pediatr , vol.122 , pp. 609-619
    • Group, H.S.1
  • 9
    • 0037194716 scopus 로고    scopus 로고
    • High-frequency oscillatory ventilation versus conventional mechanical ventilation for very-low-birth-weight infants
    • Courtney SE, Durand DJ, Asselin JM, et al: High-frequency oscillatory ventilation versus conventional mechanical ventilation for very-low-birth-weight infants. N Engl J Med 347:643-652, 2002
    • (2002) N Engl J Med , vol.347 , pp. 643-652
    • Courtney, S.E.1    Durand, D.J.2    Asselin, J.M.3
  • 10
    • 0037194703 scopus 로고    scopus 로고
    • High-frequency oscillatory ventilation for the prevention of chronic lung disease of prematurity
    • Johnson AH, Peacock JL, Greenough A, et al: High-frequency oscillatory ventilation for the prevention of chronic lung disease of prematurity. N Engl J Med 347: 633-642, 2002
    • (2002) N Engl J Med , vol.347 , pp. 633-642
    • Johnson, A.H.1    Peacock, J.L.2    Greenough, A.3
  • 11
    • 0028330460 scopus 로고
    • A controlled trial of intravenous immune globulin to reduce nosocomial infections in very-low-birth-weight infants
    • National Institute of Child Health and Human Development Neonatal Research Network
    • Fanaroff AA, Korones SB, Wright LL, et al: A controlled trial of intravenous immune globulin to reduce nosocomial infections in very-low-birth-weight infants. National Institute of Child Health and Human Development Neonatal Research Network. N Engl J Med 330:1107-1113, 1994
    • (1994) N Engl J Med , vol.330 , pp. 1107-1113
    • Fanaroff, A.A.1    Korones, S.B.2    Wright, L.L.3
  • 12
    • 0033738861 scopus 로고    scopus 로고
    • Preterm infants with low immunoglobulin G levels have increased risk of neonatal sepsis but do not benefit from prophylactic immunoglobulin G
    • Sandberg K, Fasth A, Berger A, et al: Preterm infants with low immunoglobulin G levels have increased risk of neonatal sepsis but do not benefit from prophylactic immunoglobulin G. J Pediatr 137:623-628, 2000
    • (2000) J Pediatr , vol.137 , pp. 623-628
    • Sandberg, K.1    Fasth, A.2    Berger, A.3
  • 13
    • 0041354297 scopus 로고    scopus 로고
    • Parenteral nutrition: Energy, carbohydrate, protein, and fat
    • Groh-Wargo S, Thompson M, Cox J, (ed). Chicago, IL, Precept Press, Inc
    • Sapsford A: Parenteral nutrition: energy, carbohydrate, protein, and fat, in Groh-Wargo S, Thompson M, Cox J, (ed): Parenteral Nutrition: Energy, Carbohydrate, Protein, and Fat. Chicago, IL, Precept Press, Inc, 2000, p. 128
    • (2000) Parenteral Nutrition: Energy, Carbohydrate, Protein, and Fat , pp. 128
    • Sapsford, A.1
  • 14
    • 0030904577 scopus 로고    scopus 로고
    • Six-month outcome of critically ill patients given glutamine-supplemented parenteral nutrition
    • Griffiths RD, Jones C, Palmer TE: Six-month outcome of critically ill patients given glutamine-supplemented parenteral nutrition. Nutrition 13:295-302, 1997
    • (1997) Nutrition , vol.13 , pp. 295-302
    • Griffiths, R.D.1    Jones, C.2    Palmer, T.E.3
  • 15
    • 0027102761 scopus 로고
    • Clinical and metabolic efficacy of glutamine-supplemented parenteral nutrition after bone marrow transplantation. A randomized, double-blind, controlled study
    • Ziegler TR, Young LS, Benfell K, et al: Clinical and metabolic efficacy of glutamine-supplemented parenteral nutrition after bone marrow transplantation. A randomized, double-blind, controlled study. Ann Intern Med 116:821-828, 1992
    • (1992) Ann Intern Med , vol.116 , pp. 821-828
    • Ziegler, T.R.1    Young, L.S.2    Benfell, K.3
  • 16
    • 0030071930 scopus 로고    scopus 로고
    • The effects of glutamine-supplemented parenteral nutrition in premature infants
    • Lacey JM, Crouch JB, Benfell K, et al: The effects of glutamine-supplemented parenteral nutrition in premature infants. JPEN J Parenter Enteral Nutr 20:74-80, 1996
    • (1996) JPEN J Parenter Enteral Nutr , vol.20 , pp. 74-80
    • Lacey, J.M.1    Crouch, J.B.2    Benfell, K.3
  • 17
    • 4243443080 scopus 로고    scopus 로고
    • Parenteral glutamine supplementation in ELBW infants: A multicenter randomized trial
    • Poindexter BB, Ehrenkranz RA, Stoll BJ, et al. Parenteral glutamine supplementation in ELBW infants: a multicenter randomized trial. Pediatr Res 51:317A, 2002
    • (2002) Pediatr Res , vol.51
    • Poindexter, B.B.1    Ehrenkranz, R.A.2    Stoll, B.J.3
  • 18
    • 0022498018 scopus 로고
    • Prevention of intraventricular hemorrhage in very low birth weight infants by maternally administered phenobarbital
    • Morales WJ, Koerten J: Prevention of intraventricular hemorrhage in very low birth weight infants by maternally administered phenobarbital. Obstet Gynecol 68: 295-299, 1986
    • (1986) Obstet Gynecol , vol.68 , pp. 295-299
    • Morales, W.J.1    Koerten, J.2
  • 19
    • 0024256517 scopus 로고
    • Antenatal phenobarbital in preventing intraventricular hemorrhage in premature newborns
    • De Carolis S, De Carolis MP, Caruso A, et al: Antenatal phenobarbital in preventing intraventricular hemorrhage in premature newborns. Fetal Ther 3:224-229, 1988
    • (1988) Fetal Ther , vol.3 , pp. 224-229
    • De Carolis, S.1    De Carolis, M.P.2    Caruso, A.3
  • 20
    • 0025608188 scopus 로고
    • Antenatal phenobarbital for the prevention of periventricular and intraventricular hemorrhage: A double-blind, randomized, placebo-controlled, multihospital trial
    • Kaempf JW, Porreco R, Molina R, et al: Antenatal phenobarbital for the prevention of periventricular and intraventricular hemorrhage: a double-blind, randomized, placebo-controlled, multihospital trial. J Pediatr 117:933-938, 1990
    • (1990) J Pediatr , vol.117 , pp. 933-938
    • Kaempf, J.W.1    Porreco, R.2    Molina, R.3
  • 21
    • 0002590962 scopus 로고
    • Prevention of periventricular-intraventricular hemorrhage
    • Sinclair J, Bracken M (eds), Oxford University Press
    • Horbar J: Prevention of periventricular-intraventricular hemorrhage, in Sinclair J, Bracken M (eds): Prevention of Periventricular-intraventricular Hemorrhage Oxford, Oxford University Press, 1992, pp 562-589
    • (1992) Prevention of Periventricular-intraventricular Hemorrhage Oxford , pp. 562-589
    • Horbar, J.1
  • 22
    • 0030841377 scopus 로고    scopus 로고
    • The effect of antenatal phenobarbital therapy on neonatal intracranial hemorrhage in preterm infants
    • Shankaran S, Papile L, Wright LL, et al: The effect of antenatal phenobarbital therapy on neonatal intracranial hemorrhage in preterm infants. N Engl J Med 337: 466-471, 1997
    • (1997) N Engl J Med , vol.337 , pp. 466-471
    • Shankaran, S.1    Papile, L.2    Wright, L.L.3
  • 23
    • 0020048392 scopus 로고
    • Hypertensive peaks in the pathogenesis of intraventricular hemorrhage in the newborn: Abolition by phenobarbitone sedation
    • Wimberley PD, Lou HC, Pedersen H, et al: Hypertensive peaks in the pathogenesis of intraventricular hemorrhage in the newborn: Abolition by phenobarbitone sedation. Acta Paediatr Scand 71:537-542, 1982
    • (1982) Acta Paediatr Scand , vol.71 , pp. 537-542
    • Wimberley, P.D.1    Lou, H.C.2    Pedersen, H.3
  • 24
    • 0000961958 scopus 로고    scopus 로고
    • The effects of Aquaphor original ointment on nosocomial sepsis rates and skin integrity in infants of birth wieght 501 to 1000 grams
    • Edwards W, Conner JM, Soll RF: The effects of Aquaphor original ointment on nosocomial sepsis rates and skin integrity in infants of birth wieght 501 to 1000 grams. Pediatr Res 50:388A, 2001
    • (2001) Pediatr Res , vol.50
    • Edwards, W.1    Conner, J.M.2    Soll, R.F.3
  • 25
    • 0029913031 scopus 로고    scopus 로고
    • Topical ointment therapy benefits premature infants
    • Nopper AJ, Horii KA, Sookdeo-Drost S, et al: Topical ointment therapy benefits premature infants. J Pediatr 128:660-669, 1996
    • (1996) J Pediatr , vol.128 , pp. 660-669
    • Nopper, A.J.1    Horii, K.A.2    Sookdeo-Drost, S.3
  • 26
    • 0036117785 scopus 로고    scopus 로고
    • Evidence-based neonatology: Making a difference beyond discharge from the neonatal nursery
    • Harrold J, Schmidt B: Evidence-based neonatology: Making a difference beyond discharge from the neonatal nursery. Curr Opin Pediatr 14:165-169, 2002
    • (2002) Curr Opin Pediatr , vol.14 , pp. 165-169
    • Harrold, J.1    Schmidt, B.2
  • 27
    • 0035143082 scopus 로고    scopus 로고
    • Do we measure the right end points? A systematic review of primary outcomes in recent neonatal randomized clinical trials
    • Zhang B, Schmidt B: Do we measure the right end points? A systematic review of primary outcomes in recent neonatal randomized clinical trials. J Pediatr 138: 76-80, 2001
    • (2001) J Pediatr , vol.138 , pp. 76-80
    • Zhang, B.1    Schmidt, B.2
  • 28
    • 0023933432 scopus 로고
    • Administration of indomethacin for the prevention of periventricular-intraventricular hemorrhage in high-risk neonates
    • Hanigan WC, Kennedy G, Roemisch F, et al: Administration of indomethacin for the prevention of periventricular-intraventricular hemorrhage in high-risk neonates. J Pediatr 112:941-947, 1988
    • (1988) J Pediatr , vol.112 , pp. 941-947
    • Hanigan, W.C.1    Kennedy, G.2    Roemisch, F.3
  • 29
    • 0028327237 scopus 로고
    • Low-dose indomethacin and prevention of intraventricular hemorrhage: A multicenter randomized trial
    • Ment LR, Oh W, Ehrenkranz RA, et al: Low-dose indomethacin and prevention of intraventricular hemorrhage: A multicenter randomized trial. Pediatrics 93: 543-550, 1994
    • (1994) Pediatrics , vol.93 , pp. 543-550
    • Ment, L.R.1    Oh, W.2    Ehrenkranz, R.A.3
  • 30
    • 0020068913 scopus 로고
    • Prophylactic indomethacin therapy for patent ductus arteriosus in very-low-birth-weight infants
    • Mahony L, Carnero V, Brett C, et al: Prophylactic indomethacin therapy for patent ductus arteriosus in very-low-birth-weight infants. N Engl J Med 306:506-510, 1982
    • (1982) N Engl J Med , vol.306 , pp. 506-510
    • Mahony, L.1    Carnero, V.2    Brett, C.3
  • 31
    • 0023720146 scopus 로고
    • Prophylactic indomethacin for prevention of intraventricular hemorrhage in premature infants
    • Bandstra ES, Montalvo BM, Goldberg RN, et al: Prophylactic indomethacin for prevention of intraventricular hemorrhage in premature infants. Pediatrics 82:533-542, 1988
    • (1988) Pediatrics , vol.82 , pp. 533-542
    • Bandstra, E.S.1    Montalvo, B.M.2    Goldberg, R.N.3
  • 32
    • 0023584402 scopus 로고
    • Prevention of symptomatic patent ductus arteriosus with a single dose of indomethacin
    • Krueger E, Mellander M, Bratton D, et al: Prevention of symptomatic patent ductus arteriosus with a single dose of indomethacin. J Pediatr 111:749-754, 1987
    • (1987) J Pediatr , vol.111 , pp. 749-754
    • Krueger, E.1    Mellander, M.2    Bratton, D.3
  • 33
    • 0035963517 scopus 로고    scopus 로고
    • Long-term effects of indomethacin prophylaxis in extremely-low-birth-weight infants
    • Schmidt B, Davis P, Moddemann D, et al: Long-term effects of indomethacin prophylaxis in extremely-low-birth-weight infants. N Engl J Med 344:1966-1972, 2001
    • (2001) N Engl J Med , vol.344 , pp. 1966-1972
    • Schmidt, B.1    Davis, P.2    Moddemann, D.3
  • 34
    • 0034054222 scopus 로고    scopus 로고
    • Outcome of children in the indomethacin intraventricular hemorrhage prevention trial
    • Ment LR, Vohr B, Allan W, et al: Outcome of children in the indomethacin intraventricular hemorrhage prevention trial. Pediatrics 105:485-491, 2000
    • (2000) Pediatrics , vol.105 , pp. 485-491
    • Ment, L.R.1    Vohr, B.2    Allan, W.3
  • 35
    • 0034956802 scopus 로고    scopus 로고
    • Childhood neglect and cognitive development in extremely low birth weight infants: A prospective study
    • Strathearn L, Gray PH, O'Callaghan F, et al: Childhood neglect and cognitive development in extremely low birth weight infants: a prospective study. Pediatrics 108: 142-151, 2001
    • (2001) Pediatrics , vol.108 , pp. 142-151
    • Strathearn, L.1    Gray, P.H.2    O'Callaghan, F.3
  • 36
    • 0019918210 scopus 로고
    • Babies at double hazard: Early development of infants at biologic and social risk
    • Escalona SK: Babies at double hazard: Early development of infants at biologic and social risk. Pediatrics 70:670-676, 1982
    • (1982) Pediatrics , vol.70 , pp. 670-676
    • Escalona, S.K.1
  • 37
    • 0035136307 scopus 로고    scopus 로고
    • Impact of family structure and stability on academic outcome in preterm children at 10 years of age
    • Gross S, Mettelman B, Dye T, et al: Impact of family structure and stability on academic outcome in preterm children at 10 years of age. J Pediatr 138:169-175, 2001
    • (2001) J Pediatr , vol.138 , pp. 169-175
    • Gross, S.1    Mettelman, B.2    Dye, T.3
  • 38
    • 0028210933 scopus 로고
    • The effect of epoetin beta (recombinant human erythropoietin) on the need for transfusion in very-low-birth-weight infants
    • European Multicentre Erythropoietin Study Group
    • Maier RF, Obladen M, Scigalla P, et al: The effect of epoetin beta (recombinant human erythropoietin) on the need for transfusion in very-low-birth-weight infants. European Multicentre Erythropoietin Study Group. N Engl J Med 330:1173-1178, 1994
    • (1994) N Engl J Med , vol.330 , pp. 1173-1178
    • Maier, R.F.1    Obladen, M.2    Scigalla, P.3
  • 39
    • 0036062878 scopus 로고    scopus 로고
    • Erythropoietin treatment in extremely low birth weight infants: Blood in versus blood out
    • Ohls RK: Erythropoietin treatment in extremely low birth weight infants: Blood in versus blood out. J Pediatr 141:3-6, 2002
    • (2002) J Pediatr , vol.141 , pp. 3-6
    • Ohls, R.K.1
  • 40
    • 0035046296 scopus 로고    scopus 로고
    • Variations in intraventricular hemorrhage incidence rates among Canadian neonatal intensive care units
    • Synnes AR, Chien LY, Peliowski A, et al: Variations in intraventricular hemorrhage incidence rates among Canadian neonatal intensive care units. J Pediatr 138:525-531, 2001
    • (2001) J Pediatr , vol.138 , pp. 525-531
    • Synnes, A.R.1    Chien, L.Y.2    Peliowski, A.3
  • 41
    • 0035219722 scopus 로고    scopus 로고
    • Very low birth weight outcomes of the National Institute of Child health and human development neonatal research network, January 1995 through December 1996
    • NICHD Neonatal Research Network
    • Lemons JA, Bauer CR, Oh W, et al: Very low birth weight outcomes of the National Institute of Child health and human development neonatal research network, January 1995 through December 1996. NICHD Neonatal Research Network. Pediatrics 107:E1, 2001
    • (2001) Pediatrics , vol.107
    • Lemons, J.A.1    Bauer, C.R.2    Oh, W.3
  • 42
    • 0033600279 scopus 로고    scopus 로고
    • Vitamin A supplementation for extremely-low-birth-weight infants
    • National Institute of Child Health and Human Development Neonatal Research Network
    • Tyson JE, Wright LL, Oh W, et al: Vitamin A supplementation for extremely-low-birth-weight infants. National Institute of Child Health and Human Development Neonatal Research Network. N Engl J Med 340:1962-1968, 1999
    • (1999) N Engl J Med , vol.340 , pp. 1962-1968
    • Tyson, J.E.1    Wright, L.L.2    Oh, W.3
  • 43
    • 0023190395 scopus 로고
    • Clinical trial of vitamin A supplementation in infants susceptible to bronchopulmonary dysplasia
    • Shenai JP, Kennedy KA, Chytil F, et al: Clinical trial of vitamin A supplementation in infants susceptible to bronchopulmonary dysplasia. J Pediatr 111:269-277, 1987
    • (1987) J Pediatr , vol.111 , pp. 269-277
    • Shenai, J.P.1    Kennedy, K.A.2    Chytil, F.3
  • 44
    • 0037031061 scopus 로고    scopus 로고
    • MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: A randomised placebo-controlled trial
    • MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: A randomised placebo-controlled trial. Lancet 360:7-22, 2002
    • (2002) Lancet , vol.360 , pp. 7-22


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.