Tyloxapol attenuates the pathologic effects of endotoxin in rabbits and mortality following cecal ligation and puncture in rats by blockade of endotoxin receptor-ligand interactions

Inflammation

Volumn 27, Issue 4, 2003, Pages 175-190

  Serikov, Vladimir B ^a   Glazanova, T V ^b   Jerome, E H ^c   Fleming, N W ^d,e   Higashimori, Haruki ^e   Staub Sr , N C ^c  

^a CHILDREN S HOSPITAL OAKLAND RESEARCH INSTITUTE   (United States)

^b St Peterburg Inst of Technology   (Russian Federation)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Endotoxin; Receptor blockade; Sepsis; Shock; Tyloxapol

Indexed keywords

CD14 ANTIGEN; CD2 ANTIGEN; CD22 ANTIGEN; CD4 ANTIGEN; ENDOTOXIN; ENDOTOXIN RECEPTOR; HLA DR ANTIGEN; LIGAND; RECEPTOR; TYLOXAPOL; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN ANTIBODY COMPLEX; ARTICLE; CECUM; CELL LINE; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; ENDOTOXEMIA; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOPHARMACOLOGY; IN VITRO STUDY; INTESTINE INJURY; INTESTINE PERFORATION; LEUKOCYTE MIGRATION; LIPID DIET; MACROPHAGE; MACROPHAGE ACTIVATION; MALE; MORBIDITY; MORTALITY; NONHUMAN; PERITONITIS; PHAGOCYTOSIS; RABBIT; RAT; SEPSIS; SEPTIC SHOCK;

ANIMALS; CECUM; CELL LINE; CHO CELLS; CRICETINAE; ENDOTOXINS; HUMANS; LIGANDS; LIGATION; MACROPHAGES; MALE; MICE; POLYETHYLENE GLYCOLS; RABBITS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, IMMUNOLOGIC; SURVIVAL RATE;

ANIMALIA; MURINAE; ORYCTOLAGUS CUNICULUS;

EID: 0041883653     PISSN: 03603997     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1025108207661     Document Type: Article

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