메뉴 건너뛰기




Volumn 42, Issue 3, 2003, Pages 329-338

In vivo vascular effects of genistein on a rat model of septic shock induced by lipopolysaccharide

Author keywords

Genistein; Lipopolysaccharide; Nitric oxide synthase; Tyrosine kinase inhibitors; Vascular smooth muscle

Indexed keywords

3 NITROTYROSINE; ACETYLCHOLINE; ARGININE; DAIDZEIN; ENDOTOXIN; GENISTEIN; LIPOPOLYSACCHARIDE; MALONALDEHYDE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE; NITRITE; NORADRENALIN; PROTEIN TYROSINE KINASE INHIBITOR;

EID: 0041837596     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-200309000-00003     Document Type: Article
Times cited : (24)

References (42)
  • 3
    • 0023887807 scopus 로고
    • Peripheral vascular resistance in septic shock, its relation to outcome
    • Groeneveld AB, Natua JJ, Thijs LG. Peripheral vascular resistance in septic shock, Its relation to outcome. Intensive Care Med. 1988;14:141-147.
    • (1988) Intensive Care Med , vol.14 , pp. 141-147
    • Groeneveld, A.B.1    Natua, J.J.2    Thijs, L.G.3
  • 4
    • 0027193665 scopus 로고
    • Prevention of nitric oxide synthase induction in vascular smooth muscle cells by microtubule depolymerizing agents
    • Marczin N, Papapetropoulos A, Jilling T, et al. Prevention of nitric oxide synthase induction in vascular smooth muscle cells by microtubule depolymerizing agents. Br J Pharmacol. 1993;109:603-605.
    • (1993) Br J Pharmacol , vol.109 , pp. 603-605
    • Marczin, N.1    Papapetropoulos, A.2    Jilling, T.3
  • 5
    • 0025160233 scopus 로고
    • Incubation with endotoxin activates the L-arginine pathway in vascular tissue
    • Fleming I, Gray GA, Julou-Schaeffer G, et al. Incubation with endotoxin activates the L-arginine pathway in vascular tissue. Biochem Biophys Res Commun. 1990;171:562-568.
    • (1990) Biochem Biophys Res Commun , vol.171 , pp. 562-568
    • Fleming, I.1    Gray, G.A.2    Julou-Schaeffer, G.3
  • 6
    • 0027476883 scopus 로고
    • Nitric oxide-mediated hyporeactivity to noradrenaline precedes the induction of nitric oxide synthase in endotoxin shock
    • Szabo C, Mitchell JA, Thiemerrnann C, et al. Nitric oxide-mediated hyporeactivity to noradrenaline precedes the induction of nitric oxide synthase in endotoxin shock. Br J Pharmacol. 1993;108:786-792.
    • (1993) Br J Pharmacol , vol.108 , pp. 786-792
    • Szabo, C.1    Mitchell, J.A.2    Thiemerrnann, C.3
  • 7
    • 0029091168 scopus 로고
    • Possible involvement of tyrosine kinase in the LPS-promoted initiation of L-arginine-induced relaxation of rat aorta mediated by induction of NO synthase
    • Moritoki H, Hisayama T, Takeuchi S, et al. Possible involvement of tyrosine kinase in the LPS-promoted initiation of L-arginine-induced relaxation of rat aorta mediated by induction of NO synthase. Life Sci. 1995;57:125-130.
    • (1995) Life Sci , vol.57 , pp. 125-130
    • Moritoki, H.1    Hisayama, T.2    Takeuchi, S.3
  • 8
    • 0026736731 scopus 로고
    • Nitric oxide as a signal in blood vessels
    • Knowles RG, Moncada S. Nitric oxide as a signal in blood vessels. Trends Biochem Sci. 1992;17:399-402.
    • (1992) Trends Biochem Sci , vol.17 , pp. 399-402
    • Knowles, R.G.1    Moncada, S.2
  • 10
    • 0003055186 scopus 로고    scopus 로고
    • The role of nitric oxide in sepsis - An overview
    • Kirkeboen KA, Strand OA. The role of nitric oxide in sepsis - an overview. Acta Anaesthesiol Scand. 1999;43:275-288.
    • (1999) Acta Anaesthesiol Scand , vol.43 , pp. 275-288
    • Kirkeboen, K.A.1    Strand, O.A.2
  • 11
    • 0029986709 scopus 로고    scopus 로고
    • Comparison of the effects of aminoguanidine and N-omega-nitro-L-arginine methyl ester on the multiple organ dysfunction caused by endotoxemia in the rat
    • Wu CC, Ruetten H, Thiemermann C. Comparison of the effects of aminoguanidine and N-omega-nitro-L-arginine methyl ester on the multiple organ dysfunction caused by endotoxemia in the rat. Eur J Pharmacol. 1996;300:99-104.
    • (1996) Eur J Pharmacol , vol.300 , pp. 99-104
    • Wu, C.C.1    Ruetten, H.2    Thiemermann, C.3
  • 12
    • 0028132265 scopus 로고
    • Involvement of tyrosine kinase in the induction of cyclo-oxygenase and nitric oxide synthase by endotoxin in cultured cell
    • Akarasereenont P, Mitchell JA, Appleton I, et al. Involvement of tyrosine kinase in the induction of cyclo-oxygenase and nitric oxide synthase by endotoxin in cultured cell. Br J Pharmacol. 1994;113:1522-1528.
    • (1994) Br J Pharmacol , vol.113 , pp. 1522-1528
    • Akarasereenont, P.1    Mitchell, J.A.2    Appleton, I.3
  • 13
    • 0028365217 scopus 로고
    • Signal-transduction pathway of bacterial lipopolysaccharide-stimulated bovine vascular endothelial-cells
    • Yang ZG, Bochler PN, Carroll RC, et al. Signal-transduction pathway of bacterial lipopolysaccharide-stimulated bovine vascular endothelial-cells. Inflammation. 1994;18:221-223.
    • (1994) Inflammation , vol.18 , pp. 221-223
    • Yang, Z.G.1    Bochler, P.N.2    Carroll, R.C.3
  • 14
    • 0029032351 scopus 로고
    • Tyrosine kinases are involved with the expression of inducible nitric oxide synthase in human articular chondrocytes
    • Geng Y, Maier R, Lotz M. Tyrosine kinases are involved with the expression of inducible nitric oxide synthase in human articular chondrocytes. J Cell Physiol. 1995;163:545-554.
    • (1995) J Cell Physiol , vol.163 , pp. 545-554
    • Geng, Y.1    Maier, R.2    Lotz, M.3
  • 15
    • 0030723441 scopus 로고    scopus 로고
    • Effects of tyrosine kinase and tyrosine phosphatase inhibitors on aortic contraction and induction of nitric oxide synthase
    • Duarte J, Ocete MA, Pérez-Vizcaíno F, et al. Effects of tyrosine kinase and tyrosine phosphatase inhibitors on aortic contraction and induction of nitric oxide synthase. Eur J Pharmacol. 1997;338:25-33.
    • (1997) Eur J Pharmacol , vol.338 , pp. 25-33
    • Duarte, J.1    Ocete, M.A.2    Pérez-Vizcaíno, F.3
  • 16
    • 0030800625 scopus 로고    scopus 로고
    • Effects of tyrphostins and genistein on the circulatory failure and organ dysfunction caused by endotoxin in the rat, a possible role for protein tyrosine kinase
    • Ruetten H, Thiemerrnann C. Effects of tyrphostins and genistein on the circulatory failure and organ dysfunction caused by endotoxin in the rat, a possible role for protein tyrosine kinase. Br J Pharmacol. 1997;122:59-70.
    • (1997) Br J Pharmacol , vol.122 , pp. 59-70
    • Ruetten, H.1    Thiemerrnann, C.2
  • 17
    • 78651170765 scopus 로고
    • The effect of sympathetic nerve stimulation on vasoconstrictor responses in perfused mesenteric blood vessels of the rat
    • McGregor DD. The effect of sympathetic nerve stimulation on vasoconstrictor responses in perfused mesenteric blood vessels of the rat. J Physiol. 1965;177:21-30.
    • (1965) J Physiol , vol.177 , pp. 21-30
    • McGregor, D.D.1
  • 18
    • 0029097676 scopus 로고
    • Measurement of nitrate and nitrite in extracellular fluids, a window to systemic nitric oxide metabolism
    • Grisham MB, Johnson GG, Gautreaux MD, et al. Measurement of nitrate and nitrite in extracellular fluids, a window to systemic nitric oxide metabolism. Meth Enzymol. 1995;7:84-90.
    • (1995) Meth Enzymol , vol.7 , pp. 84-90
    • Grisham, M.B.1    Johnson, G.G.2    Gautreaux, M.D.3
  • 19
    • 0041704249 scopus 로고
    • Determination of aldehydic lipid peroxidation products, Malonaldehyde and 4-hydroxylnonenal
    • Esterbauer H, Cheeseman KH. Determination of aldehydic lipid peroxidation products, Malonaldehyde and 4-hydroxylnonenal. Meth Enzymol. 1990;113:548-555.
    • (1990) Meth Enzymol , vol.113 , pp. 548-555
    • Esterbauer, H.1    Cheeseman, K.H.2
  • 20
    • 0022186670 scopus 로고
    • Measurement of protein using bicinchoninic acid
    • Smith PK, Krohn RI, Hermanson GT, et al. Measurement of protein using bicinchoninic acid. Anal Biochem. 1985;150:76-85.
    • (1985) Anal Biochem , vol.150 , pp. 76-85
    • Smith, P.K.1    Krohn, R.I.2    Hermanson, G.T.3
  • 21
    • 0022378119 scopus 로고
    • Diminished pressor response to exogenous norepinephrine and angiotensin II in septic, unanesthetized rats, Evidence for a prostaglandin-mediated effect
    • Fink MP, Homer LD, Fletcher JR. Diminished pressor response to exogenous norepinephrine and angiotensin II in septic, unanesthetized rats, Evidence for a prostaglandin-mediated effect. J Surg Res. 1985;38:335-342.
    • (1985) J Surg Res , vol.38 , pp. 335-342
    • Fink, M.P.1    Homer, L.D.2    Fletcher, J.R.3
  • 22
    • 0030575538 scopus 로고    scopus 로고
    • Hyporeactivity of mesenteric vascular bed in endotoxin-treated rats
    • Mitolo-Chieppa D, Serio M, Potenza MA, et al. Hyporeactivity of mesenteric vascular bed in endotoxin-treated rats. Eur J Pharmacol. 1996;309:175-182.
    • (1996) Eur J Pharmacol , vol.309 , pp. 175-182
    • Mitolo-Chieppa, D.1    Serio, M.2    Potenza, M.A.3
  • 23
    • 0034730306 scopus 로고    scopus 로고
    • iNOS gene expression modulates microvascular responsiveness in endotoxin-challenged mice
    • Boyle WA, Parvathaneni LS, Bourlier V, et al. iNOS gene expression modulates microvascular responsiveness in endotoxin-challenged mice. Circ Res. 2000;87:E18-E24.
    • (2000) Circ Res , vol.87
    • Boyle, W.A.1    Parvathaneni, L.S.2    Bourlier, V.3
  • 24
    • 0029561921 scopus 로고
    • Effect endotoxin on sympathetic responses in the rat isolated perfused mesenteric bed; involvement of nitric oxide and cyclo-oxygenase products
    • Fatehi-Hassanabad Z, Furman BL, Parratt JR. Effect endotoxin on sympathetic responses in the rat isolated perfused mesenteric bed; involvement of nitric oxide and cyclo-oxygenase products. Br J Pharmacol. 1995;116:3316-3322.
    • (1995) Br J Pharmacol , vol.116 , pp. 3316-3322
    • Fatehi-Hassanabad, Z.1    Furman, B.L.2    Parratt, J.R.3
  • 25
    • 0027500612 scopus 로고
    • Induction by endotoxin of nitric oxide synthase in the rat mesentery, lack of effect on action of vasoconstrictors
    • Mitchell JA, Kohlhaas KL, Sorrentino R, et al. Induction by endotoxin of nitric oxide synthase in the rat mesentery, lack of effect on action of vasoconstrictors. Br J Pharmacol. 1993;109:265-270.
    • (1993) Br J Pharmacol , vol.109 , pp. 265-270
    • Mitchell, J.A.1    Kohlhaas, K.L.2    Sorrentino, R.3
  • 26
    • 0030056101 scopus 로고    scopus 로고
    • Alteration by lipopolysaccharide of the relationship between intracellular calcium levels and contraction in rat mesenteric artery
    • Martinez MC, Muller B, Stoclet JC, et al. Alteration by lipopolysaccharide of the relationship between intracellular calcium levels and contraction in rat mesenteric artery. Br J Pharmacol. 1996;118:1218-1222.
    • (1996) Br J Pharmacol , vol.118 , pp. 1218-1222
    • Martinez, M.C.1    Muller, B.2    Stoclet, J.C.3
  • 27
    • 0027450417 scopus 로고
    • Influence of endothelium on induction of the L-arginine-nitric oxide pathway in rat aortas
    • Fleming I, Gray GA, Stoclet JC. Influence of endothelium on induction of the L-arginine-nitric oxide pathway in rat aortas. Am J Physiol. 1993;264: H1200-H1207.
    • (1993) Am J Physiol , vol.264
    • Fleming, I.1    Gray, G.A.2    Stoclet, J.C.3
  • 28
    • 0025766599 scopus 로고
    • Coronary vasodilatation induced by endotoxin in the rabbit isolated perfused heart is nitric oxide-dependent and inhibited by dexamethasone
    • Smith REA, Palmer RMJ, Moncada S. Coronary vasodilatation induced by endotoxin in the rabbit isolated perfused heart is nitric oxide-dependent and inhibited by dexamethasone. Br J Pharmacol. 1991;104:5-6.
    • (1991) Br J Pharmacol , vol.104 , pp. 5-6
    • Smith, R.E.A.1    Palmer, R.M.J.2    Moncada, S.3
  • 29
    • 0011253580 scopus 로고    scopus 로고
    • Effects of flavonoids on rat aortic smooth muscle contractility, structure-activity relationships
    • Herrera MD, Zarzuelo A, Jiménez J, et al. Effects of flavonoids on rat aortic smooth muscle contractility, structure-activity relationships. Gen Pharmacol. 1996;27:273-277.
    • (1996) Gen Pharmacol , vol.27 , pp. 273-277
    • Herrera, M.D.1    Zarzuelo, A.2    Jiménez, J.3
  • 30
    • 0042705894 scopus 로고
    • 2+ entry is inhibited by the tyrosine kinase inhibitor genistein in fura-2-loaded human platelets
    • 2+ entry is inhibited by the tyrosine kinase inhibitor genistein in fura-2-loaded human platelets. J Physiol. 1993;459:292P.
    • (1993) J Physiol , vol.459
    • Sargeant, P.1    Sage, S.2
  • 31
    • 0027261218 scopus 로고
    • Effects of genistein, a tyrosine kinase inhibitor on platelet function
    • Ozaki Y, Yatomi Y, Jinnai Y, et al. Effects of genistein, a tyrosine kinase inhibitor on platelet function. Biochem Pharmacol. 1993;46:395-403.
    • (1993) Biochem Pharmacol , vol.46 , pp. 395-403
    • Ozaki, Y.1    Yatomi, Y.2    Jinnai, Y.3
  • 32
    • 0028343059 scopus 로고
    • Prevention of lipopolysaccharide induced lethal toxicity by tyrosine kinase inhibitors
    • Novogrodsky A, Vanichkin A, Patya M, et al. Prevention of lipopolysaccharide induced lethal toxicity by tyrosine kinase inhibitors. Science. 1994;264:1319-1322.
    • (1994) Science , vol.264 , pp. 1319-1322
    • Novogrodsky, A.1    Vanichkin, A.2    Patya, M.3
  • 33
    • 0034662864 scopus 로고    scopus 로고
    • Inactivation of catecholamines by superoxide gives new insights on the pathogenesis of septic shock
    • MacArthur H, Westfall TC, Riley DP, et al. Inactivation of catecholamines by superoxide gives new insights on the pathogenesis of septic shock. Proc Natl Acad Sci U S A. 2000;97:9753-9758.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 9753-9758
    • MacArthur, H.1    Westfall, T.C.2    Riley, D.P.3
  • 34
    • 0343371810 scopus 로고    scopus 로고
    • Antioxidants differentially affect nuclear factor κB-mediated nitric oxide synthase expression in vascular smooth muscle cells
    • Hecker M, Preß C, Schini-Kerth VB, et al. Antioxidants differentially affect nuclear factor κB-mediated nitric oxide synthase expression in vascular smooth muscle cells. FEBS Lett. 1996;380:224-228.
    • (1996) FEBS Lett , vol.380 , pp. 224-228
    • Hecker, M.1    Preß, C.2    Schini-Kerth, V.B.3
  • 35
    • 0032921588 scopus 로고    scopus 로고
    • Role of increased production of superoxide anions by NAD(P)H oxidase and xanthine oxidase in prolonged endotoxemia
    • Brandes RP, Koddenberg G, Gwinner W, et al. Role of increased production of superoxide anions by NAD(P)H oxidase and xanthine oxidase in prolonged endotoxemia. Hypertension. 1999;33:1243-1249.
    • (1999) Hypertension , vol.33 , pp. 1243-1249
    • Brandes, R.P.1    Koddenberg, G.2    Gwinner, W.3
  • 36
    • 0030854951 scopus 로고    scopus 로고
    • Endothelial dysfunction in a rat model of endotoxic shock, importance of the activation of poly(ADP-ribose) synthetase by peroxynitrite
    • Szabo C, Cuzzocrea S, Zingarelli B, et al. Endothelial dysfunction in a rat model of endotoxic shock, importance of the activation of poly(ADP-ribose) synthetase by peroxynitrite. J Clin Invest. 1997;100:723-735.
    • (1997) J Clin Invest , vol.100 , pp. 723-735
    • Szabo, C.1    Cuzzocrea, S.2    Zingarelli, B.3
  • 37
    • 0030445321 scopus 로고    scopus 로고
    • Peroxynitrite inhibition of nitric oxide synthases
    • Pasquet JP, Zou MH, Ullrich V. Peroxynitrite inhibition of nitric oxide synthases. Biochimie. 1996;78:785-791.
    • (1996) Biochimie , vol.78 , pp. 785-791
    • Pasquet, J.P.1    Zou, M.H.2    Ullrich, V.3
  • 38
    • 0028813539 scopus 로고
    • Direct and reversible inhibition of endothelial nitric oxide synthase by nitric oxide
    • Ravichandran LV, Johns RA, Rengasamy A. Direct and reversible inhibition of endothelial nitric oxide synthase by nitric oxide. Am J Physiol. 1995;268:H2216-H2223.
    • (1995) Am J Physiol , vol.268
    • Ravichandran, L.V.1    Johns, R.A.2    Rengasamy, A.3
  • 39
    • 0031033526 scopus 로고    scopus 로고
    • Soy protein isoflavones enhance coronary vascular reactivity in atherosclerotic female macaques
    • Honore EK, Williams JK, Anthony MS, et al. Soy protein isoflavones enhance coronary vascular reactivity in atherosclerotic female macaques. Fertil Steril. 1997;67:148-154.
    • (1997) Fertil Steril , vol.67 , pp. 148-154
    • Honore, E.K.1    Williams, J.K.2    Anthony, M.S.3
  • 40
    • 0034998916 scopus 로고    scopus 로고
    • Phytoestrogens restore nitric oxide-mediated relaxation in isolated pulmonary arteries from chronically hypoxic rats
    • Karamsetty MR, Klinger JR, Hill NS. Phytoestrogens restore nitric oxide-mediated relaxation in isolated pulmonary arteries from chronically hypoxic rats. J Pharmacol Exp Ther. 2001;297:968-974.
    • (2001) J Pharmacol Exp Ther , vol.297 , pp. 968-974
    • Karamsetty, M.R.1    Klinger, J.R.2    Hill, N.S.3
  • 41
    • 0033979106 scopus 로고    scopus 로고
    • Genistein supplementation and estrogen replacement therapy improve endothelial dysfunction induced by ovariectomy in rats
    • Squadrito F, Altavilla D, Squadrito G, et al. Genistein supplementation and estrogen replacement therapy improve endothelial dysfunction induced by ovariectomy in rats. Cardiovasc Res. 2000;45:454-462.
    • (2000) Cardiovasc Res , vol.45 , pp. 454-462
    • Squadrito, F.1    Altavilla, D.2    Squadrito, G.3
  • 42
    • 0028944947 scopus 로고
    • Antioxidant and antipromotional effects of the soybean isoflavone genistein
    • Wei H, Bowen R, Cai Q, et al. Antioxidant and antipromotional effects of the soybean isoflavone genistein. Proc Soc Exp Biol Med. 1995;208:124-130.
    • (1995) Proc Soc Exp Biol Med , vol.208 , pp. 124-130
    • Wei, H.1    Bowen, R.2    Cai, Q.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.