Warfarin embryopathy

Pediatric Pathology and Molecular Medicine

Volumn 22, Issue 4, 2003, Pages 277-283

  Chan, Kiat Yeong ^a   Gilbert Barness, Enid ^a,c   Tiller, George ^b  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

^b Women's Health Care Services   (United States)

^c TAMPA GENERAL HOSPITAL   (United States)

Author keywords

Calcific stippling; Choanal stenosis; Dandy Walker malformation; Ear anomalies; Warfarin embryopathy

Indexed keywords

WARFARIN;

ABDOMINAL SURGERY; ADULT; ANTICOAGULATION; AORTA COARCTATION; ARTICLE; BILOBED LUNG; BONE RADIOGRAPHY; CASE REPORT; CONGENITAL HEART MALFORMATION; EAR MALFORMATION; EARFOLD ATRESIA; EMBRYOPATHY; FEMALE; FETUS DISEASE; FETUS ECHOGRAPHY; GASTROSCHISIS; GESTATIONAL AGE; HEART VENTRICLE SEPTUM DEFECT; HUMAN; HYDROCEPHALUS; HYPOPLASIA; LUNG EMBOLISM; LUNG MALFORMATION; NOSE HYPOPLASIA; NOSE MALFORMATION; PREGNANCY TERMINATION; PRIORITY JOURNAL; SKELETAL STIPPLING;

ABNORMALITIES, DRUG-INDUCED; ABORTION, INDUCED; ADULT; AFRICAN CONTINENTAL ANCESTRY GROUP; ANTICOAGULANTS; BIOPSY; ENDOSCOPY; FEMALE; FETUS; HUMANS; PREGNANCY; PREGNANCY COMPLICATIONS; PREGNANCY OUTCOME; PREGNANCY TRIMESTER, SECOND; STOMACH NEOPLASMS; ULTRASONOGRAPHY, PRENATAL; WARFARIN;

EID: 0041816100     PISSN: 15227952     EISSN: None     Source Type: Journal    
DOI: 10.1080/15227950307712     Document Type: Article

References (24)

1. Wong V, Cheng CH, Chan KC. Fetal and neonatal outcome of exposure to anticoagulants during pregnancy. Am J Med Genet 1993;45:17-21.
2. Howe AM, Webster WS. The warfarin embryopathy: a rat model showing maxillonasal hypoplasia and other skeletal disturbances. Teratology 1992;46:379-390.
3. Vitali E, Donatelli F, Quaini E, Groppelli G, Pellegrini A. Pregnancy in patients with mechanical prosthetic heart valves. Our experience regarding 98 pregnancies in 57 patients. J Cardiovasc Surg 1986;27:221-227.
4. Zakzouk MS. The congenital warfarin syndrome. J Laryngol Otol 1986;100:215-219.
5. Lamontagne JM, Leclerc JE, Carrier C, Bureau M. Warfarin embryopathy - a case report. J Otolaryngol 1984;13:127-129.
6. Raivio KO, Ikonen E, Saarikoski S. Fetal risks due to warfarin therapy during pregnancy. Acta Paediatr Scand 1977;66:735-739.
7. Barr M Jr, Burdi AR. Warfarin-associated embryopathy in a 17-week- old abortus. Teratology 1976;14:129-134.
8. Savarirayan R. Common phenotype and etiology in warfarin embryopathy and X-linked chondrodysplasia punctata (CDPX). Pediatr Radiol 1999;29:322.
9. Struwe FE, Reinwein H, Stier R. [Coumarin embryopathy]. Radiologe 1984;24:68-71.
10. Warkany J. A warfarin embryopathy? Am J Dis Child 1975;129:287-288.
11. Chen WW, Chan CS, Lee PK, Wang RY, Wong VC. Pregnancy in patients with prosthetic heart valves: an experience with 45 pregnancies. Q J Med 1982;51 (203):358-365.
12. Kaplan LC. Congenital Dandy Walker malformation associated with first trimester warfarin: a case report and literature review. Teratology 1985;32:333-337.
13. Takano H, Smith WL, Sato Y, Kao SC. Cervical spine abnormalities and instability with myelopathy in warfarin-related chondrodysplasia: 17-year follow-up. Pediatr Radiol 1998;28:497-499.
14. Howe AM, Lipson AH, de Silva M, Ouvrier R, Webster WS. Severe cervical dysplasia and nasal cartilage calcification following prenatal warfarin exposure. Am J Med Genet 1997;71:391-396.
15. Vanzieleghem BD, Lemmerling MM, Vermeersch, et al. Imaging studies in the diagnostic workup of neonatal nasal obstruction. J Comput Assist Tomogr 2001;25:540-549.
16. Barker DP, Konje JC, Richardson JA. Warfarin embryopathy with dextrocardia and situs inversus. Acta Paediatr 1994;83:411.
17. Pati S, Helmbrecht GD. Congenital schizencephaly associated with in utero warfarin exposure. Reprod Toxicol 1994;8:115-120.
18. Taybi H, Capitanio MA. Tracheobronchial calcification: an observation in three children after mitral valve replacement and warfarin sodium therapy. Radiology 1990;176:728-730.
19. Hall BD. Warfarin embryopathy and urinary tract anomalies: possible new association. Am J Med Genet 1989;34:292-393.
20. Balde MD, Breitbach GP, Wettstein A, Hoffmann W, Bastert G. [Tetralogy of Fallot following coumarin administration in early pregnancy - an embryopathy?] Geburtshilfe Frauenheilkd 1988;48:182-183.
21. Astedt B. Antenatal drugs affecting vitamin K status of the fetus and the newborn. Semin Thromb Hemost 1995;21:364-370.
22. Pauli RM, Lian JB, Mosher DF, Suttie JW. Association of congenital deficiency of multiple vitamin K-dependent coagulation factors and the phenotype of the warfarin embryopathy: clues to the mechanism of teratogenicity of coumarin derivatives. Am J Hum Genet 1987;41:566-583.
23. Menon RK, Gill DS, Thomas M, Kernoff PB, Dandona P. Impaired carboxylation of osteocalcin in warfarin-treated patients. J Clin Endocrinol Metab 1987;64:59-61.
24. Gilbert-Barness E., ed. Potter's Pathology of the Fetus and Infant. Philadelphia: Mosby, 1997.