Design and combinatorial synthesis of N-acyl iminodiacetic acids as bongkrekic acid analogues for the inhibition of adenine nucleotide translocase

Synthesis

Volumn , Issue 11, 2003, Pages 1717-1721

  Pei, Yazhong ^a   Carroll, Amy K ^a   Anderson, Christen M ^a   Moos, Walter H ^a   Ghosh, Soumitra S ^a  

^a Migenix Inc   (United States)

Author keywords

Bongkrekic acid; Combinatorial synthesis; Library design; Mitochondria; N acyl iminodiacetic acids

Indexed keywords

ENZYME INHIBITION; ENZYMES; NITROGEN COMPOUNDS; NUCLEIC ACIDS; SYNTHESIS (CHEMICAL);

MITOCHONDRIAL PERMEABILITY TRANSITIONS (MPT);

ACETIC ACID;

ADENINE NUCLEOTIDE TRANSLOCASE; ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ATRACTYLOSIDE; BONGKREKIC ACID; N ACYLIMINODIACETIC ACID; UNCLASSIFIED DRUG;

ARTICLE; COMBINATORIAL CHEMISTRY; DRUG BINDING; DRUG DESIGN; DRUG SYNTHESIS; ENZYME INHIBITION; MITOCHONDRION; POROSITY; STRUCTURE ACTIVITY RELATION;

EID: 0041737752     PISSN: 00397881     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2003-40876     Document Type: Article

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