Embryonal Mass and Hormone-Associated Effects of Pregnancy Inducing a Differential Growth of Four Murine Tumors

Oncology Research

Volumn 13, Issue 3, 2002, Pages 147-160

  Bustuoabad, Oscar D ^a,b   Di Gianni, Pedro D ^a   Franco, Marcela ^a   Kordon, Edith C ^a,b   Vanzulli, Silvia I ^a   Meiss, Roberto P ^a   Grion, Lorena C ^a   Díaz, Graciela S ^a   Nosetto, Sergio H ^a   Hockl, Pablo ^a   Lombardi, M Gabriela ^a   Pasqualini, Christiane Dosne ^a,b   Ruggiero, Raúl A ^a,b  

^a INST DE INVEST HEMATOLOGICAS   (Argentina)

^b Facultad de Ciencias Naturales e Instituto M Lillo   (Argentina)

Author keywords

Embryonal mass; Hormone regulation; Murine tumors; Pregnancy; Tumor dormancy

Indexed keywords

ESTROGEN; ESTROGEN RECEPTOR; MEDROXYPROGESTERONE; PROGESTERONE; PROGESTERONE RECEPTOR; HORMONE; INDOMETACIN; NONSTEROID ANTIINFLAMMATORY AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARACHIDONIC ACID METABOLISM; ARTICLE; BREAST ADENOCARCINOMA; CANCER GRAFT; CANCER INHIBITION; DORMANCY; EMBRYONAL TISSUE; FEMALE; FIBROSARCOMA; HORMONAL REGULATION; HORMONE RESPONSE; LYMPHATIC LEUKEMIA; MALE; MOUSE; MOUSE MAMMARY TUMOR ONCOVIRUS; NONHUMAN; PREGNANCY; PRIORITY JOURNAL; TUMOR GROWTH; TUMOR VOLUME; ADENOCARCINOMA; ANIMAL; BAGG ALBINO MOUSE; CANCER TRANSPLANTATION; CELL DIVISION; DRUG EFFECT; EXPERIMENTAL NEOPLASM; METABOLISM; NEOVASCULARIZATION (PATHOLOGY); PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; PREGNANCY COMPLICATION; TERATOMA;

ADENOCARCINOMA; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CELL DIVISION; ESTROGENS; FEMALE; FIBROSARCOMA; HORMONES; INDOMETHACIN; LEUKEMIA, LYMPHOCYTIC; MALE; MAMMARY NEOPLASMS, EXPERIMENTAL; MICE; MICE, INBRED BALB C; NEOPLASM TRANSPLANTATION; NEOPLASMS, EXPERIMENTAL; NEOVASCULARIZATION, PATHOLOGIC; PREGNANCY; PREGNANCY COMPLICATIONS, NEOPLASTIC; PROGESTERONE; RECEPTORS, PROGESTERONE; TERATOMA;

EID: 0041728969     PISSN: 09650407     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (55)

1. Donegan, W. L. Cancer and pregnancy. CA Cancer J. Clin. 33:194-214; 1983.
2. Banks, P. M. Pregnancy and lymphoma (editorial). Arch. Pathol. Lab. Med. 109:802; 1985.
3. Goto, Y.; Nagasawa, H.; Sasaki, T.; Enami, J.; Iguchi, T. Biochemical changes during growth and regression of pregnancy dependent mammary tumors of GR/A mice. Proc. Soc. Exp. Biol. Med. 209:343-353; 1995.
4. Van Nie, R.; Dux, A. Biological and morphological characteristics of mammary tumors in GR mice. J. Natl. Cancer Inst. 46:885-897; 1971.
5. Heston, W. E.; Vlahakis, G.; Tsubura, Y. Strain DD, a new high mammary tumor strain and comparison of DD with strain C3H. J. Natl. Cancer Inst. 32:237-251; 1964.
6. Huynh, H.; Alpert, L.; Pllak, M. Pregnancy-dependent growth of mammary tumors is associated with overexpression of insulin-like growth factor II. Cancer Res. 56:3651-3654; 1996.
7. Guinee, V. F.; Olsson, H.; Moller, T.; Hess, K. R.; Taylor, S. H.; Fahey, T.; Gladikov, J. V.; Vander Blink, J. W.; Bonichon, F.; Dische, S.; Yates, J. W.; Cleton, F. J. Effect of pregnancy on prognosis for young women with breast cancer. Lancet 343:1587-1589; 1994.
8. Ganeopola, G. A.; Gritsman, A. Y.; Asimakopulos, N.; Yiengpruksawan, A. Are pancreatic tumors hormone-dependent?: A case report of unusual rapid growing pancreatic tumor during pregnancy; its possible relationship to female sex hormones, and review of the literature. Ann. Surg. 65:105-111; 1999.
9. Isla, A.; Alvarez, F.; González, A., García Granole, A.; Pérez-Alvarez, M.; García Blazquez, M. Brain tumor and pregnancy. Obstet. Gynecol. 89:19-23; 1997.
10. Marchant, D. J. Breast cancer in pregnancy. Clin. Obstet. Gynecol. 37:993-997; 1994.
11. Ioachin, H. L.; Moroson, H. Lymphoma and pregnancy: Clinical observations and experimental investigations. Leukemia 8:5198-5201; 1994.
12. Nugent, P.; O'Connell, T. Breast cancer and pregnancy. Arch. Surg. 120:1221-1224; 1985.
13. Sutton, R.; Buzdar, A. U.; Hortobagyi, G. N. Pregnancy and offspring after chemotherapy in breast cancer patients. Cancer 65:847-850; 1990.
14. Grubbs, C. J.; Hill, D. L.; Farnell, D. R. Suppression of methylnitrosourea (NMU)-induced mammary cancers by pregnancy: Elimination of preneoplastic cells. Proc. Am. Assoc. Cancer Res. 26:194; 1985.
15. Gullino, P. M.; Grantham, F.H.; Hill, D. M.; Pestigrew, H. M. Effect of pregnancy and nursing on the growth of metastases from N-nitroso-N-methylurea-induced mammary carcinomas. J. Natl. Cancer Inst. 74:229-234; 1985.
16. Ioachim, H. L.; Moroson, H. Protective effect of pregnancy against transplantation of lymphomas in rats. J. Natl. Cancer Inst. 77:809-814; 1986.
17. Moroson, H.; Ioachin, H. L. Protection by grafts of embryonal rat tissues (teratomas) against induction and transplantation of malignant tumors. Cancer Res. 55:3664-3668; 1995.
18. Moroson, H.; Ioachim, H. L. Induction and transplantation of malignant nitrosomethylurea-tumor inhibited by grafts of embryonal rat tissues. Proc. Am. Assoc. Cancer Res. 30:47; 1989.
19. Ruggiero, R. A.; Bustuoabad, O. D.; Cramer, P.; Bonfil, R. D.; Pasqualini, C. D. "Concomitant immunity" in murine tumours of non-detectable immunogenicity. Br. J. Cancer 51:37-48; 1985.
20. Zahalka, M. A.; Okon, E.; Naor, D. Blocking lymphoma invasiveness with a monoclonal antibody directed against the β-chain of the leukocyte adhesion molecule (CD18). J. Immunol. 150:4466-4477; 1993.
21. Kordon, E.; Lanari, C.; Molinolo, A. A.; Elizalde, P. V.; Charreau, E. H.; Pasqualini, C. D. Estrogen inhibition of MPA-induced mouse mammmary tumor transplants. Int. J. Cancer 49:900-905; 1991.
22. Golovkina, T. V.; Piazzon, I.; Nepomnaschy, I.; Buggiano, V.; de Olano Vela, M.; Ross, S. R. Generation of a tumorigenic milk-borne mouse mammary tumor virus by recombination between endogenous and exogenous viruses. J. Virol. 71:3895-3903; 1997.
23. Attia, M. A.; Weiss, D. W. Immunology of spontaneous mammary carcinomas in mice. V. Acquired tumor resistance and enhancement in strain A mice infected with mammary tumor virus. Cancer Res. 26:1787-1800; 1966.
24. Molinolo, A. A.; Lanari, C.; Charreau, E. H.; Sanjuan, N.; Pasqualini, C. D. Mouse mammary tumors induced by medroxyprogesterone acetate: Immunohistochemistry and hormonal receptors. J. Natl. Cancer Inst. 79: 1341-1350; 1987.
25. McCormack, J. T.; Greenwald, G. S. Progesterone and oestradiol-17β concentrations in the peripheral plasma during pregnancy in the mouse. J. Endocrinol. 62:101-107; 1974.
26. Virgo, B. B.; Bellward, G. D. Serum progesterone levels in the pregnant and postpartum laboratory mouse. Endocrinology 95:1486-1490; 1974.
27. Calandra, R. S.; Charreau, E. H.; Royer, de Giaroli, M.; Baldi, A.; Calvo, J. C.; Pujato, D.; Arrighi, L. Receptores para esteroides y prolactina en carcinomas mamarios murinos. Medicina (Buenos Aries) 40:718-725; 1980.
28. Lanari, C.; Kordon, E.; Molinolo, A. A.; Pasqualini, C. D.; Charreau, E. H. Mammary adenocarcinomas induced by medroxyprogesterone acetate. Hormone dependence and EGF receptors of BALB/c in vivo sublines. Int. J. Cancer 43:845-850; 1989.
29. di Gianni, P. D.; Bonfil, R. D.; Genovese, J. A.; Dran, G.; Meiss, R. P. ; Bustuoabad, O. D. Abrogation of neovascularization in tumor-bearing mice: A putative explanation of concomitant resistance. J. Exp. Clin. Cancer Res. 14:189-195; 1995.
30. Rao, V. S.; Bonavida, B.; Zighelboim, J.; Fahey, J. L. Preferential induction of serum blocking activity and enhancement of skin allograft by soluble alloantigen. Transplantation 17:568-575; 1974.
31. Ruggiero, R. A.; Bustuoabad, O. D.; Cramer, P.; Bonfil, R. D.; Pasqualini, C. D. Correlation between seric antitumor activity and concomitant resistance in mice bearing non immunogenic tumors. Cancer Res. 50:7159-7165; 1990.
32. Kordon, R. E.; Guerra, F.; Molinolo, A. A.; Elizalde, P. V.; Charreau, E. H.; Pasqualini, C. D. Effect of sialoadenectomy on medroxyprogesterone-acetate-induced mammary carcinogenesis in BALB/c mice. Correlation between histology and epidermal growth factor receptor content. Int. J. Cancer 59:196-203; 1994.
33. Franco, M.; Bustuoabad, O. D.; di Gianni, P. D.; Goldman, A.; Pasqualini, C. D.; Ruggiero, R. A. A serum-mediated mechanism for concomitant resistance shared by immunogenic and non immunogenic murine tumors. Br. J. Cancer 74:178-186; 1996.
34. Folkman, J. Angiogenesis in cancer, vascular rheumatoid and other disease. Nat. Med. 1:77-81; 1995.
35. O'Reilly, M. S.; Holmgren, L.; Chen, C.; Folkman, J. Angiostatin induces and sustains dormancy of human primary tumors in mice. Nat. Med. 2:689-692; 1996.
36. Folkman, J. The vascularization of tumors. Sci. Am. 234:58-73; 1976.
37. Bustuoabad, O. D.; Genovese, J. A.; Pasqualini, C. D. Abrogation of concomitant tumor immunity in mice. Comun. Biol. (Argentina) 2:423-430; 1984.
38. Weish, C. W.; Nagasawa, H. Prolactin and murine mammary tumorigenesis: A review. Cancer Res. 37:951-963; 1977.
39. Russo, I. H.; Koszalka, M.; Russo, J. Human chorionic gonadotropin and rat mammary cancer prevention. J. Natl. Cancer Inst. 82:1286-1289; 1990.
40. Bakhle, Y. S. Synthesis and catabolism of cyclo-oxygenase products. Br. Med. Bull. 39:214-218; 1983.
41. Blair, I. A. Measurement of eicosanoids by gas chromatography and mass spectrometry. Br. Med. Bull. 39:223-226; 1983.
42. O'Reilly, M. S.; Holmgren, L.; Shing, Y.; Chen, C.; Rosenthal, R. A.; Moses, M.; Lane, W. S.; Cao, Y.; Sage, E. H.; Folkman, J. Angiostantin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma. Cell 79:315-328; 1994.
43. Trincheri, G.; Perussia, B. Immune interferon: A pleiotropic lymphokine with multiple effects. Immunol. Today 6:705-724; 1985.
44. Beutler, B.; Cerami, A. Cachectin and tumor necrosis factor as two sides of the same biological coin. Nature 320:584-588; 1986.
45. Keski-Oja, J.; Postlethwaite, A. E.; Moses, H. L. Transforming growth factors in the regulation of malignant cell growth and invasion. Cancer Invest. 6:705-724; 1988.
46. Folkman, J. Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat. Med. 1:77-81; 1995.
47. Bohem, T.; Folkman, J.; Browder, T.; O'Reilly, M. S. Antiangiogenic therapy of experimental cancer does not induce acquired drug resistance. Nature 390:404-407; 1997.
48. Wide, L.; Horson, B.; Wide, M. Chorionic gonadotropin in rodents In: Segal, S. J., ed. Chorionic gonadotropin. New York: Plenum Press; 1980:37.
49. Moroson, H.; Ioachin, H. L.; Li, G.; Tiwari, R. K. Serum from pregnant or teratoma bearing rats abrogates growth of human breast cancer cells in vitro and in vivo. Proc. Am. Assoc. Cancer Res. 36:473; 1995.
50. Rejnek, J.; Bednarik, T.; Rerabkova, E.; et al. Investigations of the influence of sera from pregnant women on the growth of cell cultures in conjunction with the occurrence of abnormal lipoprotein. Clin. Chim. Acta 8:108-115; 1965.
51. Lanari, C.; Luthy, I.; Lamb, C. A.; Fabris, V.; Pagano, E.; Helguero, L. A.; Sanjuan, N.; Merani, S.; Molinolo, A. A. Five novel hormone-responsive cell lines derived from murine mammary ductal carcinomas: In vivo and in vitro effects of estrogens and progestins. Cancer Res. 61:293-302; 2001.
52. Guba, M.; Cernaianu, G.; Koehl, G.; Geissler, E. K.; Jauch, K-W.; Anthuber, M.; Falk, W.; Steinbauer, M. A primary tumor promotes dormancy of solitary tumor cells before inhibiting angiogenesis. Cancer Res. 61:5575-5579; 2001.
53. di Gianni, P. D.; Franco, M.; Meiss, R. P.; Vanzulli, S.; Piazzón, I.; Pasqualini, C. D.; Bustuoabad, O. D.; Ruggiero, R. A. Inhibition of metastases by a serum factor associated to concomitant resistance induced by unrelated murine tumors. Oncol. Rep. 6:1073-1084;1999.
54. Prehn, R. T. Two competing influences that may explain concomitant tumor resistance. Cancer Res. 53:3266-3269; 1993.
55. Gorelik, E. Concomitant tumor immunity and the resistance to a second tumor challenge. Adv. Cancer Res. 39:71-120; 1983.