Crohn's associated NOD2 gene variants are not involved in determining susceptibility to multiple sclerosis [1]

Journal of Neurology Neurosurgery and Psychiatry

Volumn 74, Issue 8, 2003, Pages 1157-

  Sawcer, S ^a   Maranian, M ^a   Hensiek, A ^a   Roxburgh, R ^a   Gray, J ^a   Compston, Alastair ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOIMMUNE DISEASE; CONTROLLED STUDY; CROHN DISEASE; DISEASE ASSOCIATION; GENE; GENE FREQUENCY; GENE FUNCTION; GENETIC LINKAGE; GENETIC SUSCEPTIBILITY; GENOTYPE PHENOTYPE CORRELATION; HUMAN; LETTER; MAJOR CLINICAL STUDY; MULTIPLE SCLEROSIS; NOD2 GENE; PRIORITY JOURNAL;

ALLELES; CARRIER PROTEINS; CHROMOSOME MAPPING; COHORT STUDIES; CROHN DISEASE; EXONS; FRAMESHIFT MUTATION; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MULTIPLE SCLEROSIS; MUTATION, MISSENSE; NOD2 SIGNALING ADAPTOR PROTEIN;

EID: 0041704527     PISSN: 00223050     EISSN: None     Source Type: Journal    
DOI: 10.1136/jnnp.74.8.1157     Document Type: Letter

References (5)

1. Broadley SA, Deans J, Sawcer SJ, et al. Autoimmune disease in first-degree relatives of patients with multiple sclerosis. A UK survey. Brain 2000;123:1102-11.
2. Becker KG, Simon RM, Bailey-Wilson JE, et al. Clustering of non-major histocompatibility complex susceptibility candidate loci in human autoimmune diseases. Proc Natl Acad Sci USA 1998;95:9979-84.
3. Cavanaugh J. International collaboration provides convincing linkage replication in complex disease through analysis of a large pooled data set: Crohn disease and chromosome 16. Am J Hum Genet 2001;68:1165-71.
4. Hugot JP, Chamaillard M, Zouali H, et al. Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease. Nature 2001;411:599-603.
5. Ogura Y, Bonen DK, Inohara N, et al. A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease. Nature 2001;411:603-6.