Risk factors for diabetes in familial partial lipodystrophy, Dunnigan variety

Diabetes Care

Volumn 26, Issue 5, 2003, Pages 1350-1355

  Haque, Wasim A ^a   Oral, Elif Arioglu ^b   Dietz, Kelly ^c   Bowcock, Anne M ^d   Agarwal, Anil K ^a   Garg, Abhimanyu ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^d WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LEPTIN; TRIACYLGLYCEROL;

ADULT; AGED; ANTHROPOMETRIC PARAMETERS; ARTICLE; AUTOSOMAL DOMINANT DISORDER; BODY MASS; CONTROLLED STUDY; DIABETES MELLITUS; DISEASE PREDISPOSITION; FAMILIAL PARTIAL LIPODYSTROPHY; FAMILY HISTORY; FEMALE; GENE MUTATION; GENETIC CODE; GENOTYPE; HUMAN; INSULIN RESISTANCE; LIPODYSTROPHY; MALE; MISSENSE MUTATION; NULLIPARA; PREVALENCE; RISK FACTOR; SKINFOLD THICKNESS; TRIACYLGLYCEROL BLOOD LEVEL;

ADIPOSE TISSUE; ADULT; AGED; CROSS-SECTIONAL STUDIES; DIABETES MELLITUS; FEMALE; HUMANS; LAMIN TYPE A; LIPODYSTROPHY; MALE; MIDDLE AGED; MUTATION, MISSENSE; RISK FACTORS;

EID: 0041667987     PISSN: 01495992     EISSN: None     Source Type: Journal    
DOI: 10.2337/diacare.26.5.1350     Document Type: Article

References (27)

1. Dunnigan MG, Cochrane MA, Kelly A, Scott JW: Familial lipoatrophic diabetes with dominant transmission: a new syndrome. Q J Med 43:33-48, 1974
2. Jackson SN, Howlett TA, McNally PG, O'Rahilly S, Trembath RC: Dunnigan-Kobberling syndrome: an autosomal dominant form of partial lipodystrophy. Q J Med 90:27-36, 1997
3. Robbins DC, Horton ES, Tulp O, Sims EA: Familial partial lipodystrophy: complications of obesity in the non-obese? Metab Clin Exp 31:445-452, 1982
4. Haque WA, Vuitch F, Garg A: Postmortem findings in patients with familial partial lipodystrophy, Dunnigan variety. Diabet Med 19:1022-1025, 2002
5. Garg A, Peshock RM, Fleckenstein JL: Adipose tissue distribution pattern in patients with familial partial lipodystrophy (Dunnigan variety). J Clin Endocrinol Metab 84:170-174, 1999
6. Cao H, Hegele RA: Nuclear lamin A/C R482Q mutation in Canadian kindreds with Dunnigan-type familial partial lipodystrophy. Hum Mol Genet 9:109-112, 2000
7. Speckman RA, Garg A, Du F, Bennett L, Veile R, Arioglu E, Taylor SI, Lovett M, Bowcock AM: Mutational and haplotype analyses of families with familial partial lipodystrophy (Dunnigan variety) reveal recurrent missense mutations in the globular C-terminal domain of lamin A/C. Am J Hum Genet 66:1192-1198, 2000
8. Shackleton S, Lloyd DJ, Jackson SN, Evans R, Niermeijer MF, Singh BM, Schmidt H, Brabant G, Kumar S, Durrington PN, Gregory S, O'Rahilly S, Trembath RC: LMNA, encoding lamin A/C, is mutated in partial lipodystrophy. Nat Genet 24:153-156, 2000
9. Peters JM, Barnes R, Bennett L, Gitomer WM, Bowcock AM, Garg A: Localization of the gene for familial partial lipodystrophy (Dunnigan variety) to chromosome 1q21-22. Nat Genet 18:292-295, 1998
10. Garg A: Gender differences in the prevalence of metabolic complications in familial partial lipodystrophy (Dunnigan variety). J Clin Endocrinol Metab 85:1776-1782, 2000
11. Garg A, Vinaitheerthan M, Weatherall PT, Bowcock AM: Phenotypic heterogeneity in patients with familial partial lipodystrophy (Dunnigan variety) related to the site of missense mutations in lamin A/C gene. J Clin Endocrinol Metab 86:59-65, 2001
12. Garg A, Spackman RA, Bowcock AM: Multisystem dystrophy syndrome due to novel missense mutations in the amino-terminal head and alpha-helical rod domains of the lamin A/C gene. Am J Med 112:549-555, 2002
13. Jackson AS, Pollock ML, Ward A: Generalized equations for predicting body density of women. Med Sci Sports Exercise 12:175-181, 1980
14. Jackson AS, Pollock ML: Generalized equations for predicting body density of men. Br J Nutr 40:497-504, 1978
15. Feldman R, Sender AJ, Siegelaub AB: Difference in diabetic and nondiabetic fat distribution patterns by skinfold measurements. Diabetes 18:478-486, 1969
16. Abate N, Garg A, Peshock RM, Stray-Gundersen J, Adams-Huet B, Grundy SM: Relationship of generalized and regional adiposity to insulin sensitivity in men with NIDDM. Diabetes 45:1684-1693, 1996
17. Kritz-Silverstein D, Barrett-Connor E, Wingard DL: The effect of parity on the later development of non-insulin-dependent diabetes mellitus or impaired glucose tolerance. N Engl J Med 321:1214-1219, 1989
18. Boyko EJ, Alderman BW, Keane EM, Baron AE: Effects of childbearing on glucose tolerance and NIDDM prevalence. (erratum appears in Diabetes Care 13:1138, 1990). Diabetes Care 13:848-854, 1990
19. Haffner SM: Diabetes, hyperlipidemia, and coronary artery disease. Am J Cardiol 83:17F-21F, 1999
20. Haffner SM, Mykkanen L, Festa A, Burke JP, Stern MP: Insulin-resistant prediabetic subjects have more atherogenic risk factors than insulin-sensitive prediabetic subjects: implications for preventing coronary heart disease during the prediabetic state. Circulation 101:975-980, 2000
21. Ruhl CE, Everhart JE: Leptin concentrations in the United States: relations with demographic and anthropometric measures. Am J Clin Nutr 74:295-301, 2001
22. Haque WA, Shimomura I, Matsuzawa Y, Garg A: Serum adiponectin and leptin levels in patients with lipodystrophies. J Clin Endocrinol Metab 87:2395, 2002
23. Weyer C, Funahashi T, Tanaka S, Hotta K, Matsuzawa Y, Pratley RE, Tataranni PA: Hypoadiponectinemia in obesity and type 2 diabetes: close association with insulin resistance and hyperinsulinemia. J Clin Endocrinol Metab 86:1930-1935, 2001
24. Hotta K, Funahashi T, Arita Y, Takahashi M, Matsuda M, Okamoto Y, Iwahashi H, Kuriyama H, Ouchi N, Maeda K, Nishida M, Kihara S, Sakai N, Nakajima T, Hasegawa K, Muraguchi M, Ohmoto Y, Nakamura T, Yamashita S, Hanafusa T, Matsuzawa Y: Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients. Arterioscler Thromb Vasc Biol 20:1595-1599, 2000
25. Shaten BJ, Smith GD, Kuller LH, Neaton JD: Risk factors for the development of type II diabetes among men enrolled in the usual care group of the Multiple Risk Factor Intervention Trial. Diabetes Care 16:1331-1339, 1993
26. Ramachandran A, Snehalatha C, Viswanathan V, Viswanathan M, Haffner SM: Risk of noninsulin dependent diabetes mellitus conferred by obesity and central adiposity in different ethnic groups: a comparative analysis between Asian Indians, Mexican Americans and Whites. Diabetes Res Clin Pract Suppl 36:121-125, 1997
27. Haffner SM, Valdez RA, Hazuda HP, Mitchell BD, Morales PA, Stern MP: Prospective analysis of the insulin-resistance syndrome (syndrome X). Diabetes 41:715-722, 1992