Contribution of organic anion transporting polypeptide OATP-C to hepatic elimination of the opioid pentapeptide analogue [D-Ala2, D-Leu5]-enkephalin

Journal of Pharmacy and Pharmacology

Volumn 55, Issue 7, 2003, Pages 1013-1020

  Nozawa, Takashi ^a   Tamai, Ikumi ^a,c,d   Sai, Yoshimichi ^a,c   Nezu, Jun Ichi ^b   Tsuji, Akira ^a,c  

^a KANAZAWA UNIVERSITY   (Japan)

^b CHUGAI PHARMACEUTICAL CO LTD   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^d TOKYO UNIVERSITY OF SCIENCE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOHIPPURIC ACID; BROMSULFOPHTHALEIN; CARBON 14; CARNITINE; CATION; CHOLECYSTOKININ OCTAPEPTIDE; CHOLIC ACID; CYCLOSPORIN; DIGOXIN; DRUG METABOLITE; ENKEPHALIN[2 DEXTRO ALANINE 5 DEXTRO LEUCINE]; ENKEPHALIN[2,5 DEXTRO PENICILLAMINE]; ESTRONE SULFATE; INULIN; LEUCINE ENKEPHALIN; OLIGOPEPTIDE; OPIATE PEPTIDE; ORGANIC ANION TRANSPORTER; PENICILLAMINE; PENTAPEPTIDE; PEPTIDE DERIVATIVE; QUINIDINE; TAUROCHOLIC ACID; TETRAPEPTIDE; TETRYLAMMONIUM; TRIPEPTIDE; TRITIUM; UNCLASSIFIED DRUG; ZWITTERIONIC CARNITINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANION TRANSPORT; ARTICLE; BILE; CELL ISOLATION; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG BLOOD LEVEL; DRUG DISPOSITION; DRUG INHIBITION; EXTRACELLULAR FLUID; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LIVER CELL; LIVER CLEARANCE; NONHUMAN; OOCYTE; RAT; STRUCTURE ACTIVITY RELATION; SYSTEMIC CIRCULATION; XENOPUS LAEVIS;

ANIMALS; ANIONS; BILE; BIOLOGICAL TRANSPORT; ENKEPHALIN, D-PENICILLAMINE (2,5)-; ENKEPHALIN, LEUCINE-2-ALANINE; ESTRONE; HEPATOCYTES; INJECTIONS, INTRAVENOUS; OOCYTES; ORGANIC ANION TRANSPORT POLYPEPTIDE C; PEPTIDES; RATS; RATS, SPRAGUE-DAWLEY; STRUCTURE-ACTIVITY RELATIONSHIP; XENOPUS LAEVIS;

EID: 0041664945     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/0022357021440     Document Type: Article

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