The role of nitric oxide in vascular headache

Pharmacy World and Science

Volumn 25, Issue 4, 2003, Pages 146-151

  Van der Kuy, Paul Hugo M ^a   Lohman, Joseph J H M ^b  

^a MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^b Sittard Geleen Heerlen   (Netherlands)

Author keywords

Experimental vascular headache; Histamine; Migraine; Nitric oxide; Nitroglycerin; NO cGMP pathway; Vascular headache

Indexed keywords

(3 CHLOROPHENYL)PIPERAZINE; ACENOCOUMAROL; ACETYLCYSTEINE; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CHANNEL BLOCKING AGENT; CHLORPROMAZINE; GLYCERYL TRINITRATE; HISTAMINE; HISTAMINE H1 RECEPTOR ANTAGONIST; HYDROXOCOBALAMIN; INDOMETACIN; METHYSERGIDE; METOCLOPRAMIDE; N(G) METHYLARGININE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; OXYGEN; PINDOLOL; PIZOTIFEN; PROPRANOLOL; RESERPINE; SEROTONIN 2 ANTAGONIST; SUMATRIPTAN;

CLINICAL TRIAL; DRUG EFFECT; EXPERIMENTATION; HISTORY OF MEDICINE; HUMAN; HYPOTHESIS; MIGRAINE; REVIEW; SYNTHESIS; VASCULAR HEADACHE;

HISTAMINE; HISTORY, 19TH CENTURY; HISTORY, 20TH CENTURY; HUMANS; MIGRAINE DISORDERS; NITRIC OXIDE; NITRIC OXIDE DONORS; NITROGLYCERIN; OCCUPATIONAL DISEASES; VASCULAR HEADACHES; VASODILATOR AGENTS;

EID: 0041661914     PISSN: 09281231     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1024800512790     Document Type: Review

References (57)

1. Marsh N, Marsh A. A short history of nitroglycerin and nitric oxide in pharmacology and physiology. Clin Exp Pharmacol Physiol 2000; 27: 313-9.
2. Hughes R, Dake JA. Cyclopedia of drug pathogenesy. New York: Boerike and Tafel, 1888.
3. Hering C. Glonoine, a new medicine for headache etc. Am J Homeopathy 1849; 4: 3.
4. Field AG. On the toxicology and medicinal properties of nitrate of oxyde of glycerine. Med Times Gazette 1858; 16: 291.
5. Brunton L. Therapeutics of the circulation. London: Murray, 1908.
6. Nickerson M. Vasodilator drugs. In: Goodman LS, Gilman A, editors. The Pharmacological basis of therapeutics, 4th edition. London: Macmillan, 1980.
7. Schwartz AM. The cause, relief and prevention of headaches arising from contact with dynamite. N Engl J Med 1946; 235: 541-4.
8. Bredt DS. Endogenous nitric oxide synthesis: biological functions and pathophysiology. Free Radic Res 1999; 31: 577-96.
9. Knowles RG, Moncada S. Nitric oxide synthases in mammals. Biochem J 1994; 298: 249-58.
10. Thomsen LL. Investigations into the role of nitric oxide and the large intracranial arteries in migraine headache. Cephalalgia 1997; 17: 873-95.
11. Rand MJ. Nitrergic transmission: nitric oxide as a mediator of non-adrenergic, non-cholinergic neuro-effector transmission. Clin Exp Pharmacol Physiol 1992; 19: 147-69.
12. Tassorelli C, Joseph SA, Buzzi MG, Nappi G. The effects on the central nervous system of nitroglycerin - putative mechanisms and mediators. Prog Neurobiol 1999; 57: 607-24.
13. Wei EP, Moskowitz MA, Boccalini P and Kontos HA. Calcitonin gene-related peptide mediates nitroglycerin and sodium nitroprusside induced vasodilatation in feline cerebral arterioles. Circ Res 1992; 70: 1313-9.
14. Olesen J, Thomsen LL, Lassen LH, Olesen IJ. The nitric oxide hypothesis of migraine and other vascular headaches. Cephalalgia 1995; 15: 94-100.
15. Friberg L, Olesen J, Skyhoj Olsen T, Karle A, Ekman R, Fahrenkrug J. Absence of vasoactive peptide release from brain to cerebral circulation during onset of migraine with aura. Cephalalgia 1994; 14: 47-54.
16. Pedersen-Bjerregard U, Nielsen LB, Jensen K, Edvinsson L, Jansen I, Olesen J. Calcitonin gene-related peptide, neurokinin A and substance P: effects on nociception and neurogenic inflammation in human skin and temporal muscle. Peptides 1991; 12: 333-7.
17. Ferrari MD, Saxena PF. On serotonin and migraine: a clinical and pharmacological review. Cephalalgia 1993; 13: 151-6.
18. Jensen K, Tuxen C, Pedersen-Bjerregard U, Jansen I, Edvinsson L, Olesen J. Pain and tenderness in human temporal muscle induced by bradykinin and 5-hydroxytryptamine. Peptides 1990; 11: 1127-32.
19. Iversen HK, Olesen J, Tfelt-Hansen P. Intravenous nitroglycerin as an experimental model of vascular headache. Basic characteristics. Pain 1989; 38: 17-24.
20. Iversen HK, Nielsen TH, Tfelt-Hansen P, Olesen J. Lack of tolerance of headache and radial artery diameter during a 7 hour intravenous infusion of nitroglycerin. Eur J Clin Pharmacol 1993; 44: 47-50.
21. Olesen J, Thomsen LL, Iversen H. Nitric oxide is a key molecule in migraine and other vascular headaches. Trends Pharmacol Sci 1994; 149: 149-53.
22. Olesen J, Iversen HK, Thomsen LL. Nitric oxide hypersensitivity. A possible molecular mechanism of migraine pain. Neuroreport 1993; 4: 1027-30.
23. Thomsen LL, Kruuse C, Iversen HK, Olesen J. A nitric oxide donor (nitroglycerin) triggers genuine migraine attacks. Eur J Neurol 1994; 1: 73-80.
24. Lassen LH, Thomsen LL, Kruuse C, Iversen HK, Olesen J. Histamine-1 receptor blockade does not prevent nitroglycerin induced migraine. Eur J Clin Pharmacol 1996;49:335-9.
25. Iversen HK, Olesen J. Headache induced by a nitric oxide donor (nitroglycerin) responds to sumatriptan. A human model for development of migraine drugs. Cephalalgia 1996;16:412-18.
26. Shekhar YC, Anand IS, Sarma R, Ferrari R, Wahi PL, Poole-Wilson PA. Effects of prolonged infusion of human alpha calcitonin gene related peptide on hemodynamics, renal blood flow and hormone levels in congestive heart failure. Am J Cardiol 1991; 67: 732-6.
27. Rudinger, Jansen-Olesen. Headache research seminar Kopenhagen, 1996.
28. Iversen HK. N-acetylcysteine enhances nitroglycerin-induced headache and cranial arterial responses. Clin Pharmacol Ther 1992;52:125-33.
29. Ekbom K. Nitroglycerin as a provocative agent in cluster headache. Arch Neurol 1968; 19: 487-93.
30. Hannerz J, Hellstrøm G, Klum T, Wahlgren NG. Cluster headache and dynamite headache: blood flow velocities in the middle cerebral artery. Cephalalgia 1990; 10: 31-8.
31. Dahl A, Russell D, Nyberg-Hansen R, Rootwell K. Cluster headache: transcranial Doppler ultrasound and rCBF studies. Cephalalgia 1990; 10: 87-94.
32. Krabbe AE, Olesen J. Headache provocation by continuous intravenous infusion of histamine. Clinical results and receptor mechanisms. Pain 1980; 8: 253-9.
33. Olesen J, Lassen LH. Experimental headache induced by histamine, meta-chlorphenylpiperazine and reserpine. In: Olesen J, Moskowitz MA, editors. Experimental headache models. Philadelphia: Lippincott-Raven Publishers, 1995.
34. Hibbs JB, Taintor RR, Vavrin Z, Rachlin EM. Nitric oxide: a cytotoxic activated macrophage effector molecule. Biochem Biophys Res Commun 1988; 157: 87-94.
35. Arregui A, Carera J, Leon-Velarde F, Paredes S, Viscarra D, Arbaiza D. High prevalence of migraine in high-altitude population. Neurology 1991; 41: 1668-9.
36. Park KH, Rubin LE, Gross SS, Levi R. Nitric oxide is a mediator of hypoxic coronary vasodilatation. Relation to adenosine and cyclo oxygenase-derived metabolites. Circ Res 1992; 71: 992-1000.
37. Iwamoto J, Yoshinaga M, Yang SP, Krasney E, Krasney J. Methylene blue inhibits hypoxic cerebral vasodilatation in awake sheep. J Appl Physiol 1992; 73: 226-32.
38. Lüscher TF, Vanhoutte PM. The endothelium: modulator of cardiovascular functions. Boston: Chemical Rubber Company Press, 1990: 1-228
39. Kudrow L. Response of cluster headache attacks to oxygen inhalation. Headache 1981; 21: 1-14.
40. Vanhoutte PM. Platelet-derived serotonin, the endothelium, and cardiovascular disease. J Cardiovasc Pharmacol 1991; 179 (Suppl 5): S6-12.
41. Peatfield RC, Gawel MJ, Rose FC. The effect of infused prostacyclin in migraine and cluster headache. Headache 1981; 21: 190-5.
42. Brewerton TP, Murphy DL, Mueller EA, Jimerson IC. Induction of migraine-like headaches by the serotonin agonist mchlorophenylpiperazine. Clin Pharmacol Ther 1988; 43: 605-9.
43. Gordon ML, Lipton RB, Brown SL, Nakraseive C, Russel M, Pollack SZ et al. Headache and cortisol responses to mchlorophenylpiperazine are highly correlated. Cephalalgia 1993;13:400-5.
44. Fozard JR, Kalkman HO. 5-Hydroxytryptamine and the initiation of migraine: new perspectives. Naunyn Schmiedebergs Arch Pharmacol 1994; 350: 225-9.
45. Fog-Moller F, Bryndum B, Dalsgaard-Nielsen F, Kemp Genefke I 1, Nattero G. Therapeutic effect of reserpine on migraine syndrome: relationship to blood amine levels. Headache 11976; 15: 275-81.
46. Iversen HK, Olesen J. The effect of sumatriptan on nitroglycerin-(NTG)-induced headache and vascular responses. Cephalalgia 1993; 13 (Suppl) 13: 186.
47. Tfelt-Hansen P, De Vries P, Saxena PR. Triptans in migraine: a comparative review of pharmacology, pharmacokinetics and efficacy. Drugs 2000; 60: 1259-87.
48. Glusa E, Richter M. Endothelium-dependent relaxation of porcine pulmonary arteries via 5-HTlc-like receptors. Naunyn Schmiedebergs Arch Pharmacol 1993; 347: 471-7.
49. Martin GR, Browning C, Giles M. Further characterization of an atypical 5-HT receptor mediating endothelium-dependent vasorelaxation. Br J Pharmacol 1993; 110: 137.
50. Wilson JR, Foresman BH, Gamber RG, Wright T. Hyperbaric oxygen in the treatment of migraine with aura. Headache 1998; 38(2): 112-5.
51. Alvarez WC, Mason AY. Results obtained in the treatment of headache with the inhalation of pure oxygen. Mayo Clin Proc 1940; 15: 616-8.
52. Schoedon G, Blau N, Schneemann M, Flury G, Schaffner A. Nitric oxide production depends on preceding tetrahydrobiopterin synthesis by endothelial cells: selective suppression of induced nitric oxide production by sepiapterin reductase inhibitors. Biochem Biophys Res Commun 1994; 199: 504-10.
53. Lassen LH, Ashina M, Christiansen I, Ulrich V, Grover R, Donaldson J, Olesen I. Nitric oxide synthase inhibition: a new principle in the treatment of migraine attacks. Cephalalgia 1998; 18: 27-32.
54. Ashina M, Lassen LH, Bendtsen L, Jensen R, Olesen J. Effect of inhibition of nitric oxide synthase on chronic tension-type headache: a randomised crossover trial. Lancet 1999; 353: 287-89.
55. Kelly AM, Ardagh M, Curry C, D'Antonio J, Zebic S. Intravenous chlorpromazine versus intramuscular sumatriptan for acute migraine. J Accid Emerg Med 1997; 14: 209-11.
56. Li CG, Rand MJ. Effects of hydroxocobalamin and carboxy PTIO on nitrergic transmission in porcine anococcygeus and retractor penis muscles. Br J Pharmacol 1999; 127: 172-6.
57. Van der Kuy P-HM, Merkus FWHM, Lohman JJHM, ter Berg JWM, Hooymans PM. Nasal hydroxocobalamin in the prophylaxis of migraine: an open study. Cephalalgia 1999; 19: 374-5.