Estimation of the lipophilicity of antiarrhythmic and antihypertensive active 1-substituted pyrrolidin-2-one and pyrrolidine derivatives

Biomedical Chromatography

Volumn 17, Issue 5, 2003, Pages 318-324

  Kulig, Katarzyna ^a   Malawska, Barbara ^a  

^a JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE   (Poland)

Author keywords

Partition coefficient; Quantitative structure activity relationship; Reversed phase chromatography

Indexed keywords

THIN LAYER CHROMATOGRAPHY;

HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY; LIPOPHILICITY; PARTITION COEFFICIENT; PYRROLIDIN-2-ONES; PYRROLIDINE DERIVATIVES; QUANTITATIVE STRUCTURE ACTIVITY RELATIONSHIP; REVERSED PHASE CHROMATOGRAPHY; REVERSED-PHASE HIGH PERFORMANCE; REVERSED-PHASE THIN-LAYER CHROMATOGRAPHY; TRIS BUFFERS;

HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

1 (2 ACETOXY 3 ARYLPIPERAZINE)PROPYLPYRROLIDIN 2 ONE; 1 (2 HYDROXY 3 ARYLPIPERAZINE)PROPYLPYRROLIDIN 2 ONE; ACETONITRILE; ALPHA 2 ADRENERGIC RECEPTOR; ANTIARRHYTHMIC AGENT; ANTIHYPERTENSIVE AGENT; PYRROLIDINE DERIVATIVE; TROMETAMOL; UNCLASSIFIED DRUG;

ARTICLE; CALCULATION; COMPARATIVE STUDY; COMPUTER PROGRAM; CONTROLLED STUDY; LIPOPHILICITY; PARTITION COEFFICIENT; QUANTITATIVE STRUCTURE ACTIVITY RELATION; RECEPTOR AFFINITY; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; THIN LAYER CHROMATOGRAPHY;

EID: 0041562585     PISSN: 02693879     EISSN: None     Source Type: Journal    
DOI: 10.1002/bmc.246     Document Type: Article

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