Depletion of naive CD4 T cells by CXCR4-using HIV-1 variants occurs mainly through increased T-cell death and activation

AIDS

Volumn 17, Issue 10, 2003, Pages 1419-1424

  Hazenberg, Mette D ^a   Otto, Sigrid A ^a   Hamann, Dörte ^a   Roos, Marijke Th L ^a   Schuitemaker, Hanneke ^a   De Boer, Rob J ^b   Miedema, Frank ^a,c  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

^c SANQUIN RESEARCH   (Netherlands)

Author keywords

CXCR4 using HIV 1 variants; Naive T cells; T cell subsets; T cell turnover; Thymus

Indexed keywords

CD4 ANTIGEN; CHEMOKINE RECEPTOR CXCR4;

ADULT; ARTICLE; CELL DEATH; CELL DIVISION; CELL SUBPOPULATION; COHORT ANALYSIS; CONTROLLED STUDY; EFFECTOR CELL; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; IN VITRO STUDY; LYMPHOCYTE COUNT; MAJOR CLINICAL STUDY; MEMORY CELL; PRIORITY JOURNAL; SCID MOUSE; T LYMPHOCYTE ACTIVATION; THYMOCYTE; THYMUS FUNCTION;

ADULT; ANTIGENS, CD27; CD4 LYMPHOCYTE COUNT; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL DEATH; CELL DIVISION; FLOW CYTOMETRY; HIV INFECTIONS; HIV-1; HUMANS; IMMUNOLOGIC MEMORY; LYMPHOCYTE ACTIVATION; LYMPHOCYTE COUNT; PROSPECTIVE STUDIES; RECEPTORS, CCR5; RECEPTORS, CXCR4; STATISTICS, NONPARAMETRIC; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES, REGULATORY; VIRAL LOAD;

EID: 0041524852     PISSN: 02699370     EISSN: None     Source Type: Journal    
DOI: 10.1097/00002030-200307040-00001     Document Type: Article

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