Oncology drug discovery applications using the FMAT™ 8100 HTS system

Journal of Biomolecular Screening

Volumn 8, Issue 1, 2003, Pages 81-88

  Lee, Jennifer Y ^a,b   Miraglia, Sheri ^c   Yan, Xiongwei ^c   Swartzman, Elana ^c   Cornell Kennon, Susan ^a   Mellentin Michelotti, Julia ^c   Bruseo, Charles ^a,d   France, Dennis S ^a,e  

^a NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c APPLIED BIOSYSTEMS   (United States)

^d GLAXOSMITHKLINE   (United States)

^e NOVARTIS PHARMA AG   (Switzerland)

Author keywords

Anticancer agents; Assay platforms; High throughput screening; Oncology

Indexed keywords

ANTINEOPLASTIC AGENT; GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; LIPOCORTIN 5; NATURAL PRODUCT; PROTEIN SH2; PROTEIN TYROSINE KINASE; STAUROSPORINE; STREPTAVIDIN; GRB2 PROTEIN, HUMAN; PROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

APOPTOSIS; ARTICLE; COLORECTAL CARCINOMA; CONTROLLED STUDY; CYTOTOXICITY; DRUG DETERMINATION; DRUG DISCOVERY; DRUG TARGETING; ENZYME ASSAY; ENZYME LINKED IMMUNOSORBENT ASSAY; FLUORESCENT LINKED IMMUNOSORBENT ASSAY; FLUOROMETRY; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; BIOASSAY; DRUG EFFECT; INSTRUMENTATION; METHODOLOGY; NEOPLASM; PHARMACOLOGY; PHYSIOLOGY;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANNEXIN A5; ANTINEOPLASTIC AGENTS; APOPTOSIS; BIOLOGICAL ASSAY; GRB2 ADAPTOR PROTEIN; HUMANS; NEOPLASMS; PHARMACOLOGY; PROTEINS; SRC-FAMILY KINASES;

EID: 0041466457     PISSN: 10870571     EISSN: None     Source Type: Journal    
DOI: 10.1177/1087057102239668     Document Type: Article

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