Ligand-receptor binding measured by laser-scanning imaging

Proceedings of the National Academy of Sciences of the United States of America

Volumn 96, Issue 20, 1999, Pages 11122-11127

  Zuck, Paul ^b   Lao, Zhege ^b   Skwish, Stephen ^b   Glickman, J Fraser ^b   Yang, Ke ^b   Burbaum, Jonathan ^b   Inglese, James ^a,b  

^a MERCK RESEARCH LABORATORIES   (United States)

^b PHARMACOPEIA INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYANINE DYE; CYTOKINE RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; HYBRID PROTEIN; PHOSPHATASE; POLYSTYRENE;

ANIMAL CELL; ARTICLE; BINDING KINETICS; CHO CELL; CYTOMETRY; ENZYME ASSAY; FLUOROMETRY; LASER MICROSCOPY; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR BINDING;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CHO CELLS; CRICETINAE; FLOW CYTOMETRY; GRB2 ADAPTOR PROTEIN; GTP-BINDING PROTEINS; LASERS; LIGANDS; PHOSPHORIC MONOESTER HYDROLASES; PROTEINS; RECEPTORS, CELL SURFACE; RECEPTORS, CYTOKINE; SRC HOMOLOGY DOMAINS;

ANIMALIA;

EID: 0033613125     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.96.20.11122     Document Type: Article

References (27)

1. Debouck, C. & Goodfellow, P. N. (1999) Nat. Genet. 21, 48-50.
2. Chabala, J. C. (1998) in Comb. Chem. Mol. Diversity Drug Discovery, eds. Gordon, E. M. & Kerwin, J. F., Jr. (Wiley-Liss, New York), pp. 3-15.
3. Hart, H. E. & Greenwald, E. B. (1979) Mol. Immunol. 16, 265-267.
4. Hemmila, I. & Webb, S. (1997) Drug Discovery Today 2, 373-381.
5. Tsien, R. Y., Bacskai, B. J. & Adams, S. R. (1993) Trends Cell Biol. 3, 242-245.
6. Auer, M., Moore, K. J., Meyer-Almes, F. J., Guenther, R., Pope, J. & Stoeckli, K. A. (1998) Drug Discovery Today 3, 457-465.
7. Lynch, B. A., Loiacono, K. A., Tiong, C. L., Adams, S. E. & MacNeil, I. A. (1997) Anal. Biochem. 247, 77-82.
8. Kamentsky, L. A. & Kamentsky, L. D. (1991) Cytometry 12, 381-387.
9. Dietz, L. J., Dubrow, R. S., Manian, B. S. & Sizto, N. L. (1996) Cytometry 23, 177-186.
10. Ernst, L. A., Gupta, R. K., Mujumdar, R. B. & Waggoner, A. S. (1989) Cytometry 10, 3-10.
11. Inglese, J., Samama, P., Patel, S., Burbaum, J., Stroke, I. L. & Appell, K. C. (1998) Biochemistry 37, 2372-2377.
12. Ji, T. H., Grossmann, M. & Ji, I. (1998) J. Biol. Chem. 273, 17299-17302.
13. Watson, S. & Arkinstall, S. (1994) The G Protein Linked Receptor Facts Book (Academic, London).
14. Luttrell, L. M., Daaka, Y. & Lefkowitz, R. J. (1999) Curr. Opin. Cell Biol. 11, 177-183.
15. Baggiolini, M., Dewald, B. & Moser, B. (1997) Annu. Rev. Immunol. 15, 675-705.
16. Nicola, N. A. (1994) Guidebook to Cytokines and Their Receptors (Oxford Univ. Press, New York).
17. Brown, S. J., Becherer, K. A., Blumeyer, K., Kautzer, C., Axelrod, F., Le, H., McConnell, S. J., Whalley, A. & Spinella, D. G. (1998) Protein Expression Purif. 14, 120-124.
18. Tartaglia, L. A., Dembski, M., Weng, X., Deng, N., Culpepper, J., Devos, R., Richards, G. J., Campfield, L. A., Clark, F. T., Deeds, J., et al. (1995) Cell 83, 1263-1271.
19. Pawson, T. (1995) Nature (London) 373, 573-580.
20. Lowenstein, E. J., Daly, R. J., Batzer, A. G., Li, W., Margolis, B., Lammers, R., Ullrich, A., Skolnik, E. Y., Bar-Sagi, D. & Schlessinger, J. (1992) Cell 70, 431-442.
21. Burke, T. R. J., Smyth, M. S., Otaka, A., Nomizu, M., Roller, P. P., Wolf, G., Case, R. & Shoelson, S. E. (1994) Biochemistry 33, 6490-6494.
22. Songyang, Z., Shoelson, S. E., Chaudhuri, M., Gish, G., Pawson, T., Haser, W. G., King, F., Roberts, T., Ratnofsky, S., Lechleider, R. J., et al. (1993) Cell 72, 767-778.
23. Greenlund, A. C., Morales, M. O., Viviano, B. L., Yan, H., Krolewski, J. & Schreiber, R. D. (1995) Immunity 2, 677-687.
24. Ladbury, J. E., Lemmon, M. A., Zhou, M., Green, J., Botfield, M. C. & Schlessinger, J. (1995) Proc. Natl. Acad. Sci. USA 92, 3199-3203.
25. Hopp, T. P., Prickett, K. S., Price, V. L., Libby, R. T., March, C. J., Cerretti, D. P., Urdal, D. L. & Conlon, P. J. (1988) Bio/ Technology 6, 1204-1210.
26. Spiegel, A. M. (1996) Annu. Rev. Physiol. 58, 143-170.
27. Lamb, P., Tapley, P. & Rosen, J. (1998) Drug Discovery Today 3, 122-130.