Homeostatic compensation maintains Ca2+ signaling functions in Purkinje neurons in the leaner mutant mouse

Cerebellum

Volumn 1, Issue 2, 2002, Pages 119-127

  Murchison, David ^a   Dove, Leonard S ^b   Abbott, Louise C ^c   Griffith, William H ^a  

^a TEXAS A M COLLEGE OF MEDICINE   (United States)

^b Pharmaceutical Product Development   (United States)

^c TEXAS A AND M UNIVERSITY   (United States)

Author keywords

Ca 2+ binding protein; Ca2+ buffering; Mutant mice; Voltage gated Ca2+ channels

Indexed keywords

CALCIUM BINDING PROTEIN; VOLTAGE GATED CALCIUM CHANNEL; BUFFER; CALCIUM CHANNEL;

BEHAVIOR; CALCIUM CURRENT; CALCIUM SIGNALING; CALCIUM TRANSPORT; CENTRAL NERVOUS SYSTEM; ENDOPLASMIC RETICULUM; GENE MUTATION; HOMEOSTASIS; HUMAN; MAMMAL; MOUSE MUTANT; MOUSE STRAIN; NERVOUS SYSTEM INJURY; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PURKINJE CELL; REVIEW; ANIMAL; BIOLOGICAL MODEL; BODY WEIGHT; CELL CULTURE; GENETICS; METABOLISM; MOUSE; PHYSIOLOGY; RAT;

ANIMALS; BUFFERS; CALCIUM CHANNELS; CALCIUM SIGNALING; CELLS, CULTURED; HOMEOSTASIS; HUMANS; MICE; MICE, NEUROLOGIC MUTANTS; MODELS, NEUROLOGICAL; PURKINJE CELLS; RATS; THINNESS;

EID: 0041466116     PISSN: 14734222     EISSN: 14734230     Source Type: Journal    
DOI: 10.1080/147342202753671259     Document Type: Review

References (68)

1. Denier C, Ducros A, Durr A, Eymard B, Chassande B, Tournier-Lasserve E. Missense CACNA1A mutation causing episodic ataxia type 2. Arch Neurol 2001; 58: 292-295.
2. Guida S, Trettel F, Pagnutti S, Mantuano E, Tottene A, Veneziano L, Fellin T, Spadaro M, Stauderman KA, Williams ME, Volsen S, Ophoff RA, Frants RR, Jodice C, Frontali M, Pietrobon D. Complete loss of P/Q calcium channel activity caused by a CACNA1A missense mutation carried by patients with episodic ataxia type 2. Am J Hum Genet 2001; 68: 759-764.
3. Jen J. Calcium channelopathies in the central nervous system. Curr Opin Neurobiol 1999; 9: 274-280.
4. Ophoff RA, Terwindt GM, Vergouwe MN, van Eijk R, Oefner PJ, Hoffman SMG, Lamerdin JE, Mohrenweiser HW, Bulman DE, Ferrari M, Haan J, Lindhout D, van Ommen G-JB, Hofker MH, Ferrari MD, Frants RR. Familial hemiplegic migraine and episodic ataxia type-2 are caused by mutations in the calcium channel gene CACNL1A4. Cell 1996; 87: 543-552.
5. 1A- voltage-dependent calcium channel. Nat Genet 1997; 15: 62-69.
6. Jen J, Geschwind DH. Ataxia and calcium channels. Arch Neurol 2001; 58: 179-180.
7. Heckroth JA, Abbott LC. Purkinje cell loss from alternating sagittal zones in the cerebellum of leaner mutant mice. Brain Res 1994; 658: 93-104.
8. Herrup K, Wilczynski SL. Cerebellar cell degeneration in the leaner mutant mouse. Neuroscience 1982; 7: 2185-2196.
9. Sidman RL, Green MC, Appel SH. Catalog of the neurological mutants of the mouse. Cambridge: Harvard University Press, 1965.
10. Fletcher CF, Lutz CM, O'Sullivan TN, Shaughnessy JD, Hawkes R, Frankel WN, Copeland NG, Jenkins NA. Absence epilepsy in tottering mutant mice is associated with calcium channel defects. Cell 1996; 87: 607-617.
11. 2+ channels and their possible counterparts in mammalian CNS neurons. Neuropharm 1993; 32: 1075-1088.
12. Gillard SE, Volsen SG, Smith W, Beattie RE, Bleakman D, Lodge D. Identification of pore-forming subunit of P-type calcium channels: an antisense study on rat cerebellar Purkinje cells in culture. Neuropharmacology 1997; 36: 405-409.
13. 1A subunits of brain calcium channels. J Neurosci 1995; 15: 6403-6418.
14. 2+ channels in the mammalian central nervous system. Trends Neurosci 1992; 15: 351-355.
15. Mintz IM, Adams ME, Bean BP. P-type calcium channels in rat central and peripheral neurons. Neuron 1992; 9: 85-95.
16. 1a) mice. Neuroscience 1999; 90: 717-728.
17. Miller RJ. Calcium channels prove to be real headache. Trends Neurosci 1997; 20: 189-192.
18. Dove LS, Abbott LC, Griffith WH. Whole-cell and single-channel analysis of P-type calcium currents in cerebellar Purkinje cells of leaner mutant mice. J Neurosci 1998; 18: 7687-7699.
19. Lorenzon NM, Lutz CM, Frankel WN, Beam KG. Altered calcium channel currents in Purkinje cells of the neurological mutant mouse leaner. J Neurosci 1998; 18: 4482-4489.
20. Wakamori M, Yamazaki K, Matsunodaira H, Teramoto T, Tanaka I, Niidome T, Sawada K, Nishizawa Y, Sekiguchi N, Mori E, Mori Y, Imoto K. Single tottering mutations responsible for the neuropathic phenotype of the P-type calcium channel. J Biol Chem 1998; 273: 34857-34867.
21. 1a) cerebellum. Mol Brain Res 1998; 59: 93-99.
22. Mintz IM, Venema VJ, Swiderek KM, Lee TD, Bean BP, Adams, ME. P-type calcium channels blocked by the spider toxin ω-Aga-IVA. Nature 1992; 355: 827-829.
23. Campbell DB, Hess EJ. L-type calcium channels contribute to the tottering mouse dystonic episodes. Mol Pharmacol 1999; 55: 23-31.
24. Fierro L, Llano I. High endogenous calcium buffering in Purkinje cells from rat cerebellar slices. J Physiol (Lond) 1996; 496: 617-625.
25. 28k) gene expression in the developing and aging mouse cerebellum. Mol Brain Res 1990; 8: 283-290.
26. Winsky L, Kuznicki J. Distribution of calretinin, calbindin D28k, and parvalbumin in subcellular fractions of rat cerebellum: effects of calcium. J Neurochem 1995; 65: 381-388.
27. Eilers J, Plant T, Konnerth A. Localized calcium signalling and neuronal integration in cerebellar Purkinje neurons. Cell Calcium 1996; 20: 215-226.
28. Llano I, DiPolo R, Marty A. Calcium-induced calcium release in cerebellar Purkinje cells. Neuron 1994; 12: 663-673.
29. Dove LS, Nahm S-S, Murchison D, Abbott LC, Griffith WH. Altered calcium homeostasis in cerebellar Purkinje cells of leaner mutant mice. J Neurophysiol 2000; 84: 513-524.
30. Murchison D, Griffith WH. Increased calcium buffering in basal forebrain neurons during aging. J Neurophysiol 1998; 80: 350-364.
31. Tse A, Tse FW, Hille B. Calcium homeostasis in identified rat gonadotrophs. J Physiol (Lond) 1994; 477: 511-525.
32. Grynkiewicz G, Poenie M, Tsien RY. A new generation of calcium indicators with greatly improved fluorescence properties. J Biol Chem 1985; 260: 3440-3450.
33. Verkhratsky A, Shmigol A. Calcium-induced calcium release in neurons. Cell Calcium 1996; 19: 1-14.
34. Brorson JR, Bleakman D, Gibbons SJ, Miller RJ. The properties of intracellular calcium stores in cultured rat cerebellar neurons. J Neurosci 1991; 11: 4024-4043.
35. Berridge MJ. Neuronal calcium signaling. Neuron 1998; 21: 13-26.
36. Isaacs KR, Abbott LC. Development of the paramedian lobule of the cerebellum in wild-type and tottering mice. Devel Neurosci 1992; 14: 386-393.
37. Inoue T, Lin X, Kohlmeier KA, Orr HT, Zoghbi HY. Calcium dynamics and electrophysiological properties of cerebellar Purkinje cells in SCA1 transgenic mice. J Neurophysiol 2001; 85: 1750-1760.
38. Vig PJS, Subramony SH, Burright EN, Fratkin JD, McDaniel DO, Desaiah D, Qin Z. Reduced immunoreactivity to calcium-binding proteins in Purkinje cells precedes onset of ataxia in spinocerebellar ataxia-1 transgenic mice. Neurology 1998; 50: 106-113.
39. Kaemmerer WF, Rodrigues CMP, Steer CJ, Low WC. Creatine-supplemented diet extends Purkinje cell survival in spinocerebellar ataxia type1 transgenic mice but does not prevent the ataxic phenotype. Neuroscience 2001; 103: 713-724.
40. Mullen RJ, Eicher EM, Sidman RL. Purkinje cell degeneration, a new mutation in the mouse. Proc Natl Acad Sci USA 1976; 73: 208-212.
41. Mintz IM, Sabatini BL, Regehr WG. Calcium control of transmitter release at a cerebellar synapse. Neuron 1995; 15: 675-688.
42. Regehr WG, Mintz IM. Participation of multiple calcium channel types in transmission at single climbing fiber to Purkinje cell synapses. Neuron 1994; 12: 605-613.
43. V2.1/α1A (P/Q-type) voltage-dependent calcium channel mediates inhibitory neurotransmission onto mouse cerebellar Purkinje cells. Eur J Neurosci 2001; 13: 1902-1912.
44. Dittman JS, Regehr WG. Calcium dependence and recovery kinetics of presynaptic depression at the climbing fiber to Purkinje cell synapse. J Neurosci 1998; 18: 6147-6162.
45. Kano M, Rexhausen U, Dreessen J, Konnerth A. Synaptic excitation produces a long-lasting rebound facilitation of inhibitory synaptic signals in cerebellar Purkinje cells. Nature 1992; 356: 601-604.
46. Konnerth A, Dreessen J, Augustine GJ. Brief dendritic calcium signals initiate long-lasting synaptic depression in cerebellar Purkinje cells. Proc Natl Acad Sci USA 1992; 89: 7051-7055.
47. Llano I, Leresche N, Marty A. Calcium entry increases the sensitivity of cerebellar Purkinje cells to applied GABA and decreases inhibitory synaptic currents. Neuron 1991; 6: 565-574.
48. Khodakhah K, Armstrong CM. Induction of long-term depression and rebound potentiation by inositol triphosphate in cerebellar Purkinje neurons. Proc Natl Acad Sci USA 1997; 94: 14009-14014.
49. 2+ stores, is required for the induction of LTD in cultured cerebellar Purkinje neurons. J Neurophysiol 1995; 74: 2184-2188.
50. 2+]: intracellular stores spill their guts. Neuron 1999; 22: 427-430.
51. Matsumoto M, Nakagawa T, Inoue T, Nagata E, Tanaka K, Takano H, Minowa O, Kuno J, Sakakibara S, Yamada M, Yoneshima H, Miyawaki A, Fukuuchi Y, Furuichi T, Okana H, Mikoshiba K, Noda T. Ataxia and epileptic seizures in mice lacking type 1 inositol 1,4,5-triphosphate receptor. Nature 1996; 379: 168-171.
52. Street VA, Bosma MM, Demas VP, Regan MR, Lin DD, Robinson LC, Agnew WS, Tempel BL. The type 1 inositol 1,4,5-triphosphate receptor gene is altered in the opisthotonus mouse. J Neurosci 1997; 17: 635-645.
53. 2+] at the mouth of a calcium channel. J Neurosci 1997; 17: 6961-6973.
54. 2+ signaling in neurons. Cell Calcium 1998; 24: 359-366.
55. 2+ signalling in fine dendrites and spines of cerebellar Purkinje neurons. Nature 1995; 373: 155-158.
56. Eilers J, Callewaert G, Armstrong C, Konnerth A. Calcium signaling in a narrow somatic submembrane shell during synaptic activity in cerebellar Purkinje neurons. Proc Natl Acad Sci USA 1995; 92: 10272-10276.
57. Ayata C, Shimizu-Sasamata M, Lo EH, Noebels JL, Moskowitz MA Impaired neurotransmitter release and elevated threshold for conical spreading depression in mice with mutations in the α1A subunit of P/Q type calcium channels. Neuroscience 2000; 95: 639-645.
58. Schilling K, Dickinson MH, Connor JA, Morgan JI. Electrical activity in cerebellar cultures determines Purkinje cell dendritic growth patterns. Neuron 1991; 7: 891-902.
59. Vecellio M, Schwaller B, Meyer M, Hunziker W, Celio MR. Alterations in Purkinje cell spines of calbindin D-28k and parvalbumin knock-out mice. Eur J Neurosci 2000; 12: 945-954.
60. 2+ channel-regulated neuronal gene expression. J Neurobiol 1998; 37: 171-189.
61. Ginty DD. Calcium regulation of gene expression: isn't that spatial? Neuron 1997; 18: 183-186.
62. Arnold DB, Heintz N. A calcium responsive element that regulates expression of two calcium binding proteins in Purkinje cells. Proc Natl Acad Sci USA 1997; 94: 8842-8847.
63. Austin MC, Schultzberg M, Abbott LC, Montpied P, Evers JR, Paul SM, Crawley JN. Expression of tyrosine hydroxylase in cerebellar Purkinje neurons of the mutant tottering and leaner mouse. Mol Brain Res 1992; 15: 227-240.
64. Hess EJ, Wilson MC. Tottering and leaner mutations perturb transient developmental expression of tyrosine hydroxylase in embryonically distinct Purkinje cells. Neuron 1991; 6: 123-132.
65. Fureman BE, Campbell DB, Hess EJ. L-type calcium channel regulation of abnormal tyrosine hydroxylase expression in cerebella of tottering mice. Ann NY Acad Sci 1999; 868: 217-219.
66. Nagamoto-Combs K, Piech KM, Best JA, Sun B, Tank AW. Tyrosine hydroxylase gene promoter activity is regulated by both cyclic AMP-responsive element and AP1 sites following calcium influx. J Biol Chem 1997; 272: 6051-6058.
67. + channel in cultured rat cerebellar Purkinje neurons. Eur J Neurosci 1999; 11: 735-739.
68. Raman IM, Bean BP. Ionic currents underlying spontaneous action potentials in isolated cerebellar Purkinje neurons. J Neurosci 1999; 19: 1663-1674.