Evaluation of tear film proteinases in horses with ulcerative keratitis

Veterinary Ophthalmology

Volumn 3, Issue 2-3, 2000, Pages 111-119

  Strubbe, D Todd ^a   Brooks, Dennis E ^a   Schultz, Gregory S ^a   Willis Goulet, Heather ^a   Gelatt, Kirk N ^a   Andrew, Stacy E ^a   Kallberg, Maria E ^a   Mackay, Edward O ^a   Collante, Warner R ^a  

^a University of Florida   (United States)

Author keywords

5,613; Horses; Proteases; Tears; Ulcers

Indexed keywords

EQUIDAE; FUNGI;

EID: 0041450975     PISSN: 14635216     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1463-5224.2000.00093.x     Document Type: Article

References (45)

1. Gionfriddo JR, Gionfriddo JP, Krohne SG. Ocular diseases of llamas: 194 cases 1980-1993. Journal of the American Veterinary Medical Association 1997; 210(12): 1784-1787.
2. Whitley RD, Moore CP. Microbiology of the equine eye in health and disease. Veterinary Clinics North America 1984; 6: 451-457.
3. Nasisse MP, Nelms S. Equine ulcerative keratitis. Veterinary Clinics North America: Equine Practice 1992; 8(3): 537-555.
4. Slansky HH, Gnadinger MC, Itoi M, Dohlman CH. Collagenase in corneal ulcers. Archives of Ophthalmology 1969; 82: 108-111.
5. Itoi M, Gnadinger MC, Slansky HH, Freeman MI, Dohlman CH. Collagenase in the cornea. Experimental Eye Research 1969; 8(3): 369-373.
6. Fini MF, Girard MT. Expression of collagenolytic/gelatinolytic metalloproteinases by normal cornea. Investigative Ophthalmology and Visual Science 1990; 31: 1779-1788.
7. Robertson P, Ryel R, Taylor R, Shyu K, Fullmer H. Collagenase: localization in polymorphonuclear leukocyte granules in rabbit. Science 1972; 177(43): 64-65.
8. Shams N, Hanninen L, Kenyon K. Increased gelatinolytic and caseinolytic activity in the thermally injured, nutritionally compromised rat cornea: detection of a 27-kDa lymphoreticular cell-associated caseinase. Current Eye Research 1994; 13: 11-19.
9. Kawaharajo K, Homma J. Pathogenesis of the mouse keratitis produced with Pseudomonas aeruginosa. Japanese Journal of Experimental Medicine 1975; 45: 515-524.
10. Foster C, Zeit R, Mai-Phan T, Kenyon K. Immunosuppression and selective inflammatory cell depletion. Studies on a guinea pig model of corneal ulceration after ocular alkali burning. Archives of Ophthalmology 1982; 100(11): 1820-4.
11. Willeford KO, Miller WW, Abrams KA, Vaughn BM. Modulation of proteolytic activity associated with persistent corneal ulcers in dogs. Veterinary Ophthalmology 1998; 1: 5-8.
12. Brown D, Chwa M, Escobar M, Kenney MC. Characterization of the major matrix degrading metalloproteinase of human corneal stroma. Evidence for an enzyme/inhibitor complex. Experimental Eye Research 1991; 52: 5-16.
13. Murphy G, Ward R, Hembry RM, Reynolds JJ, Kuhn K, Tryggvason K Characterization of gelatinase from pig polymorphonuclear leukocytes: a metalloproteinase resembling tumor type IV collagenase. Biochemical Journal 1989; 258: 463-472.
14. Matsubara M, Zieske J, Fini ME. Mechanism of basement membrane dissolution preceding corneal ulceration. Investigative Ophthalmology and Visual Science 1991; 32(13): 3221-3237.
15. Morel F, Berthier S, Guillot M, Zaoui P, Massoubre C, Didier F, Vignais PV. Human neutrophil gelatinase is a collagenase type IV. Biochemical and Biophysical Research Communications 1993; 191: 269-274.
16. Watanabe H, Hattori S, Katsuda S, Nakanishi I, Nagai Y. Human neutrophil elastase: Degradation of basement membrane components and immunolocalization in the tissues. Journal of Biochemistry 1990; 108: 753-759.
17. Sathe S, Sakata M, Beaton AR, Sack RA. Identification, origins and the diurnal role of the principle serine protease inhibitors in human tear fluid. Current Eye Research 1998; 17(4): 348-362.
18. Hook R, Hook C, Brown S. Fibroblast collagenase partial purification and characterization. Investigative Ophthalmology and Visual Science 1973; 12(10): 771-776.
19. Paterson C, Wells JG, Koklitis PA, Higgs GA, Docherty AJ. Recombinant tissue inhibitor of metalloproteinases type 1 suppress alkali-burn-induced corneal ulceration in rabbits. Investigative Ophthalmology and Visual Science 1994; 35: 677-684.
20. Matsubara M, Girard MT, Kublin CL, Cintron C, Fini ME. Differential roles for two gelatinolytic enzymes of the matrix metalloproteinase family in the remodeling cornea. Developmental Biology 1991; 147: 425-439.
21. Brown S. Collagenase and corneal ulcers. Investigative Ophthalmology and Visual Science 1971; 10: 203.
22. Berman M. Collagenase and corneal ulceration. In: (Woolley D, Evanson Jeds) Collagenase in Normal and Pathological Connective Tissues. John Wiley: Chicester, 1980; 140-174.
23. Twining SS, Fukuchi T, Yue BY, Wilson PM, Zhou X, Loushin G. Alpha-2 macroglobulin is present in and synthesized by the cornea. Investigative Ophthalmology and Visual Science 1994; 35: 3226-3233.
24. Berman M, Winthrop S, Ausprunk D, Rose J, Langer R, Gage J. Plasminogen activator (urokinase) causes vascularization of the cornea. Investigative Ophthalmology and Visual Science 1982; 22(2): 191-199.
25. Zieske JD, Bukusoglu G. Effect of protease inhibitors on corneal epithelial migration. Investigative Ophthalmology and Visual Science 1991; 32(7): 2073-2078.
26. Twining S, Fukuchi T, Yue B, Wilson P, Boskovic G. Corneal synthesis of alpha 1-proteinase inhibitor (alpha 1-antitrypsin). Investigative Ophthalmology and Visual Science 1994; 35: 458-462.
27. Brown S, Weller C, Akiya S. Pathogenesis of ulcers of the alkali-burned cornea. Archives of Ophthalmology 1970; 83(2): 205-208.
28. Kenyon K, Berman M, Rose J, Gage J. Prevention of stromal ulceration in the alkali-burned rabbit cornea by glued-on contact lens. Evidence for the role of polymorphonuclear leukocytes in collagen degradation. Investigative Ophthalmology and Visual Science 1979; 18(6): 570-587.
29. Dua HS, Gomes JA, Jindal VK, Appa SN, Schwarting R, Eagle RC, Donoso LA, Laibson PR. Mucosa specific lymphocytes in the human conjunctiva, corneoscleral limbus and lacrimal gland. Current Eye Research 1994; 13(1): 87-93.
30. Murayama T, Agmatine R, Ikegami Y, Nawada R, Lee WJ, Kuze F. Suppressive effects of Aspergillus fumigatus culture filtrates on human alveolar macrophages and polymorphonuclear leukocytes. European Respiratory Journal 1996; 9(2): 293-300.
31. Burns FR, Gray RD, Paterson CA. Inhibition of alkali-induced corneal ulceration and perforation by a thiol peptide. Investigative Ophthalmology and Visual Science 1990; 31(1): 107-114.
32. Wentworth JS, Paterson CA, Gray RD. Effect of a metalloproteinase inhibitor on established corneal ulcers after an alkali burn. Investigative Ophthalmology and Visual Science 1992; 33(7): 2174-2179.
33. Kessler E, Mondino BJ, Brown SI. The corneal response to Pseudomonas aeruginosa: histopathologic and enzymatic characterization. Investigative Ophthalmology and Visual Science 1977; 16(2): 116-125.
34. Ruehl WW, Marrs C, Beard MK, Shokooki V, Hinojoza JR, Banks S, Bieber D, Mattick JS. Q pili enhance the attachment of Moraxella bovis to bovine corneas in vitro. Molecular Microbiology 1993; 7(2): 285-288.
35. Zhu WS, Wojdyla K, Donlon K, Thomas PA, Eberle HI. Extracellular proteases of Aspergillus flavus. Fungal keratitis, proteases, and pathogenesis. Diagnostic Microbiology and Infectious Disease 1990; 13(6): 491-197.
36. Matsumoto K, Shams N, Hanninen L, Kenyon K. Cleavage and activation of corneal matrix metalloproteases by Pseudomonas aeruginosa proteases. Investigative Ophthalmology and Visual Science 1993; 34: 1945-1953.
37. Matsumoto K, Shams NB, Hanninen LA, Kenyon KR. Proteolytic activation of corneal matrix metalloproteinase by Pseudomonas aeruginosa elastase. Current Eye Research 1992; 11(11): 1105-1109.
38. Kirschner SE, Twining SS. The effect of Pseudomonas aeruginosa exoproducts on corneal proteases. Investigative Ophthalmology and Visual Science (Abstract) 1990; 31: 487.
39. Munger RJ. Equine ophthalmic emergencies. Veterinary Clinics North America: Large Animal Practice 1984; 6(3): 467-474.
40. McLaughlin SA, Gilger BC, Whitley RD. Infectious keratitis in horses: evaluation and management Compendium of Continuing Education for the Veterinary Practitioner 1992; 14(3): 372-379.
41. Wolf DE. Medical treatment for corneal ulcers. Proceedings of the American Association of Equine Practitioners 1996: 161-169.
42. Berman M, Barber J, Talamo R, Langley C. Corneal ulceration and the serum antiproteases. I. Alpha 1-antitrypsin. Investigative Ophthalmology and Visual Science 1973; 12: 759-770.
43. Barletta J, Angella G, Balch K, Dimova H, Stern G, Moser M, Setten G, Schultz G. Inhibition of pseudomonal ulceration in rabbit corneas by a synthetic matrix metalloproteinase inhibitor. Investigative Ophthalmology and Visual Science 1996; 37: 20-27.
44. Schultz GS, Strelow S, Stern GA et al.Treatment of alkali-injured rabbit corneas with a synthetic inhibitor of matrix metalloproteinase. Investigative Ophthalmology and Visual Science 1992; 33(12): 3325-3331.
45. Burns FR, Stack MS, Gray RD, Paterson CA. Inhibition of purified collagenase from alkali-burned rabbit corneas. Investigative Ophthalmology and Visual Science 1989; 30: 1569-1575.