Modulation of proteolytic activity associated with persistent corneal ulcers in dogs

Veterinary Ophthalmology

Volumn 1, Issue 1, 1998, Pages 5-8

  Willeford, Kenneth O ^a   Miller, William W ^b   Abrams, Kenneth L ^c   Vaughn, Bridget M ^d  

^a MISSISSIPPI STATE UNIVERSITY   (United States)

^b Animal Ophthalmology Clinic   (United States)

^c Veterinary Ophthalmology Services Inc   (United States)

^d MISSISSIPPI STATE UNIVERSITY   (United States)

Author keywords

Persistent corneal ulcers; Plasmin; Polysulpated glycosaminoglycan

Indexed keywords

ANIMALIA; CANIS FAMILIARIS;

EID: 0442276058     PISSN: 14635216     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1463-5224.1998.00001.x     Document Type: Article

References (30)

1. Berman M, Kenyon K, Hayashi K, L'Hernault N. The pathogenesis of epithelial defects and stromal ulceration. In: Cornea. (ed. Cavanagh HD). Raven: New York, 1988; 35-43.
2. Fini ME, Girard MT. Expression of collagenolytic/gelatinolytic metalloproteinases by normal cornea. Investigative Ophthalmology and Visual Science 1990; 31: 1779-1788.
3. Roberts SR. Superficial indolent ulcer of a cornea in Boxer dogs. Journal of Small Animal Practice 1966; 6: 111-115.
4. Kirschner SE, Niyo Y, Betts DM. Idiopathic persistent corneal erosions: clinical and pathological findings in 18 dogs. Journal of the American Animal Hospital Association 1989; 25: 84-90.
5. Magrane WG. Keratitis in dogs. Veterinary Scope 1956; 1: 2-10.
6. Gelatt KN, Samuelson DA. Recurrent corneal erosions and epithelial dystrophy in the boxer dog. Journal of the American Animal Hospital Association 1982; 18: 453-460.
7. Cook C, Wilcox B. A clinical and histological study of canine persistent superficial corneal ulcers. Proceedings of the American College of Veterinary Ophthalmologists 1995; 26: 139.
8. Miller WW. Use of polysulfated glycosoaminoglycans in treatment of persistent corneal erosions in dogs-a pilot clinical study. Veterinary Medicine 1996; 91: 916-922.
9. Whitley RD. Canine Cornea. In: Textbook of Veterinary Ophthalmology, (ed. Gelatt KN). Lea & Febiger: Philadelphia, 1991; 312-318.
10. Kirschner SE, Brazzell RK, Stern ME et al. The use of topical epidermal growth factor for treatment of nonhealing corneal erosions in dogs. Journal of the American Animal Hospital Association 1991; 27: 449-452.
11. Johnson BW. The use of protease inhibitors to enhance corneal epithelial wound repair. Proceedings of the American College of Veterinary Ophthalmologists 1989; 20: 54-59.
12. Morgan RV, Bachrach A, Ogilvie GK. An evaluation of soft contact lens usage in the dog and cat. Journal of the American Animal Hospital Association 1984; 20: 885-888.
13. Peiffer RL, Gelatt KN, Gwin RM. Superficial keratectomy in the management of indolent ulcers of the boxer cornea. Canine Practice 1976; 3: 31-33.
14. Champagne ES, Munger RJ. Multiple punctuate keratotomy for the treatment of recurrent epithelial erosions in dogs. Journal of the American Animal Hospital Association 1992; 28: 213-219.
15. Geggel HS. Successful treatment of recurrent corneal erosion with Nd:YAG anterior stromal puncture. American Journal of Ophthalmology 1990; 110: 404-407.
16. Morgan RV, Abrams KL. A comparison of six different therapies for persistent corneal erosions in dogs and cats. Veterinary and Comparative Ophthalmology 1994; 4: 38-43.
17. Burkhardt D, Ghosh P. Laboratory evaluation of antiarthritic drugs as potential chondroprotective agents. Seminars in Arthritis and Rheumatism 1987; 17(Suppl. 1): 3-34.
18. Menninger H, Burkhardt H, Roske W et al. Lysosomal elastase: effect of mechanical and biochemical properties of normal cartilage, inhibition by polysulfonated glycosoaminoglycan, and binding to chondrocytes. Rheumatological International 1981; 1: 73-81.
19. Pavelka K, Sedlackova M, Gatterova J et al. Glycosoaminoglycan polysulfuric acid (GAGPS) in osteoarthritis of the knee. Osteoarthritis and Cartilage 1995; 3: 15-23.
20. Romer J, Bugge TH, Pyke C et al. Impaired wound healing in mice with a disrupted plasminogen gene. Nature Medicine 1996; 2: 287-292.
21. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Analytical Biochemistry 1976; 72: 248-254.
22. SAS Institute Inc. SAS/STAT Guide for personal computers. SAS Institute Inc. Cary, NC., 1988.
23. Dua HS, Gomes JAP, Singh A. Corneal epithelial wound healing. British Journal of Ophthalmology 1994; 78: 401-408.
24. Tervo T, van Setten G-B, Beuerman RW et al. Appearance of immunohistochemically detectable cellular fibronectin and tenascin in the experimental rabbit keratectomy wound. Investigative Ophthalmology and Visual Science 1989; 30: 149.
25. Khodadoust AA, Silverstein AM, Kenyon KR et al. Adhesion of regenerating corneal epithelium. American Journal of Ophthalmology 1968; 65: 339-348.
26. Kenyon KR. Morphology and pathologic responses of the cornea to disease. In: The Cornea. (eds Smolin G, Thoft RA). Little, Brown and Company: Boston, 1987; 66-70.
27. Carreno MR, Muniz OE, Howell DS. The effect of glycosoaminoglycan polysulfuric acid ester on articular cartilage in experimental osteoarthritis: effects on morphological parameters of disease severity. Journal of Rheumatology 1986; 32: 759-766.
28. Lust G, Williams AJ, Burton-Wurster N et al. Effects of intramuscular administration of glycosoaminoglycan polysulfates on signs of incipient hip dysplasia in growing pups. American Journal of Veterinary Research 1992; 53: 1836-1843.
29. Todhunter RJ. Therapeutic principals for joint diseases and repair of articular tissues. In: Equine Surgery. (ed. Auer JA). WB Sanders Co: Philadelphia, 1992; 883-901.
30. van Setten G-B, Salonen E-M, Vaheri A et al. Plasmin and plasminogen activator activities in tear fluid during corneal wound healing after anterior keratectomy. Current Eye Research 1989; 8: 1293-1298.