Synthesis of potent Ins(1,4,5)P3 5-phosphatase inhibitors by modification of myo-inositol 1,3,4,6-tetrakisphosphate

Bioorganic and Medicinal Chemistry

Volumn 11, Issue 19, 2003, Pages 4245-4253

  Mills, Stephen J ^a   Potter, Barry V L ^a  

^a University of Bath   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DI O METHYLINOSITOL 1,3,4,6 TETRAKISPHOSPHATE; DI O METHYLINOSITOL 1,3,4,6 TETRAKISPHOSPHOROTHIONATE; ENZYME INHIBITOR; INOSITOL 1,3,4,6 TETRAKISPHOSPHATE; INOSITOL 1,3,4,6 TETRAKISPHOSPHOROTHIONATE; PHOSPHOROTHIOIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CALCIUM MOBILIZATION; CALCIUM TRANSPORT; CHEMICAL REACTION; DRUG SYNTHESIS; ENZYME INHIBITION; EVALUATION; ROOM TEMPERATURE;

EID: 0041387411     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(03)00347-X     Document Type: Article

References (22)

1. Berridge M.J. Nature. 361:1993;315.
2. Berridge M.J., Lipp P., Bootman M.D. Nat. Rev. Mol. Cell Biol. 1:2000;11.
3. Potter B.V.L., Lampe D. Angew. Chem., Int. Ed. Engl. 34:1995;1933.
4. Jiang Q.-X., Thrower E.C., Chester D.W., Ehrlich B.E., Sigworth F.J. EMBO J. 14:2002;3575.
5. Bosanac I., Alattia J.R., Mai T.K., Chan J., Talarico S., Tong F.K., Tong K.I., Yoshikawa F., Furuichi T., Iwai M., Michikawa T., Mikoshiba K., Ikura M. Nature. 420:2002;696.
6. Nahorski S.R., Potter B.V.L. Trends Pharmacol. Sci. 10:1989;139144.
7. 4. (b) Majerus P.W., Kisseleva M.V., Norris F.A. J. Biol. Chem. 274:1999;10669.
8. Tsujishita Y., Guo S., Stolz L.E., York J.D., Hurley J.H. Cell. 105:2001;379.
9. Attree O., Olivos I.M., Okabe I., Bailey L.C., Nelson D.L., Lewis R.A., McInnes R.R., Nussbaum R.L. Nature. 358:1992;239.
10. Ivorra I., Gigg R., Irvine R.F., Parker I. Biochem. J. 273:1991;317.
11. Gawler D.J., Potter B.V.L., Gigg R., Nahorski S.R. Biochem. J. 272:1990;519.
12. Safrany S.T., Mills S.J., Liu C., Lampe D., Noble N.J., Nahorski S.R., Potter B.V.L. Biochemistry. 33:1994;10763.
13. Lampe D., Liu C.S., Mahon M.F., Potter B.V.L. J. Chem. Soc., Perkin Trans. 1. 1996;1717.
14. Desai T., Gigg J., Gigg R., Payne S., Penades S., Rogers H.J. Carbohydr. Res. 216:1991;197.
15. Desai T., Gigg J., Gigg R., Payne S. Carbohydr. Res. 228:1992;65.
16. Mills S.J., Potter B.V.L. J. Chem. Soc., Perkin Trans. 1. 1997;1279.
17. Lampe D., Liu C., Potter B.V.L. J. Med. Chem. 37:1994;907.
18. Hermosura M.C., Takeuchi H., Fleig A., Riley A.M., Potter B.V.L., Hirata M., Penner R. Nature. 408:2000;735.
19. Still W.C., Kahn M., Mitra M. J. Org. Chem. 43:1978;2923.
20. Tanaka T., Tamatsukuri S., Ikehara M. Tetrahedron Lett. 27:1986;199.
21. Yu K.-L., Fraser-Reid B. Tetrahedron Lett. 29:1988;979.
22. Gigg J., Gigg R., Payne S., Conant R. J. Chem. Soc., Perkin Trans. 1. 1987;2411.