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Volumn 85, Issue 2-5, 2003, Pages 469-472

Prevention of diabetes, hepatic injury, and colon cancer with dehydroepiandrosterone

Author keywords

Dehydroepiandrosterone (DHEA); Diabetes; Troglitazone

Indexed keywords

AZOXYMETHANE; GLUCOSE 6 PHOSPHATASE; INSULIN; LIVER ENZYME; PRASTERONE; RECOMBINANT HORMONE; RECOMBINANT PRASTERONE; TROGLITAZONE; UNCLASSIFIED DRUG;

EID: 0041386392     PISSN: 09600760     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-0760(03)00219-X     Document Type: Conference Paper
Times cited : (27)

References (21)
  • 1
    • 0035850889 scopus 로고    scopus 로고
    • MRNA and enzymatic activity of hepatic 11 beta-hydroxysteroid dehydrogenase type 1 are elevated in C57BL/KsJ-db/db mice
    • Aoki K., Homma M., Hirano T., Oka K., Satoh S., Mukasa K., Ito S., Sekihara H. mRNA and enzymatic activity of hepatic 11 beta-hydroxysteroid dehydrogenase type 1 are elevated in C57BL/KsJ-db/db mice. Life Sci. 69:2001;2543-2549.
    • (2001) Life Sci. , vol.69 , pp. 2543-2549
    • Aoki, K.1    Homma, M.2    Hirano, T.3    Oka, K.4    Satoh, S.5    Mukasa, K.6    Ito, S.7    Sekihara, H.8
  • 2
    • 0016758495 scopus 로고
    • Function of the pancreatic B-cell during the development of hyperglycemia in mice homozygous for the mutations "diabetes" (db) and "misty" (m)
    • Gunnarsson R. Function of the pancreatic B-cell during the development of hyperglycemia in mice homozygous for the mutations "diabetes" (db) and "misty" (m). Diabetologia. 11:1975;431-438.
    • (1975) Diabetologia , vol.11 , pp. 431-438
    • Gunnarsson, R.1
  • 3
    • 0019942001 scopus 로고
    • Therapeutic effects of dehydroepiandrosterone (DHEA) in diabetic mice
    • Coleman D.L., Leiter E.H., Schwizer R.W. Therapeutic effects of dehydroepiandrosterone (DHEA) in diabetic mice. Diabetes. 31:1982;830-833.
    • (1982) Diabetes , vol.31 , pp. 830-833
    • Coleman, D.L.1    Leiter, E.H.2    Schwizer, R.W.3
  • 4
    • 0021334185 scopus 로고
    • Effect of genetic background on the therapeutic effects of dehydroepiandrosterone (DHEA) in diabetes-obesity mutants and aged normal mice
    • Coleman D.L., Schwizer R.W., Leiter E.H. Effect of genetic background on the therapeutic effects of dehydroepiandrosterone (DHEA) in diabetes-obesity mutants and aged normal mice. Diabetes. 33:1984;26-32.
    • (1984) Diabetes , vol.33 , pp. 26-32
    • Coleman, D.L.1    Schwizer, R.W.2    Leiter, E.H.3
  • 6
    • 0031759739 scopus 로고    scopus 로고
    • Dehydroepiandrosterone decreases serum TNF α and restores insulin sensitivity: Independent effect from secondary weight reduction in genetically obese Zucker fatty rats
    • Kimura M., Tanaka S., Yamada Y., Kikuchi Y., Yamakawa T., Sekihara H. Dehydroepiandrosterone decreases serum TNF α and restores insulin sensitivity: independent effect from secondary weight reduction in genetically obese Zucker fatty rats. Endocrinology. 139:1998;3249-3253.
    • (1998) Endocrinology , vol.139 , pp. 3249-3253
    • Kimura, M.1    Tanaka, S.2    Yamada, Y.3    Kikuchi, Y.4    Yamakawa, T.5    Sekihara, H.6
  • 10
    • 0026520193 scopus 로고
    • Molecular physiology of the regulation of hepatic gluconeogenesis and glycolysis
    • Pilkis S.J., Granner D.K. Molecular physiology of the regulation of hepatic gluconeogenesis and glycolysis. Annu. Rev. Physiol. 54:1992;885-909.
    • (1992) Annu. Rev. Physiol. , vol.54 , pp. 885-909
    • Pilkis, S.J.1    Granner, D.K.2
  • 11
    • 0032768942 scopus 로고    scopus 로고
    • Dehydroepiandrosterone suppresses the elevated hepatic glucose-6-phosphatase and fructose-1,6-bisphosphatase activities in C57BL/KsJ-db/db mice: Comparison with troglitazone
    • Aoki K., Saito T., Mukasa K., Kaneshiro M., Kawasaki S., Okamura A., Sekihara H. Dehydroepiandrosterone suppresses the elevated hepatic glucose-6-phosphatase and fructose-1,6-bisphosphatase activities in C57BL/KsJ-db/db mice: comparison with troglitazone. Diabetes. 48:1999;1579-1585.
    • (1999) Diabetes , vol.48 , pp. 1579-1585
    • Aoki, K.1    Saito, T.2    Mukasa, K.3    Kaneshiro, M.4    Kawasaki, S.5    Okamura, A.6    Sekihara, H.7
  • 12
    • 0034509709 scopus 로고    scopus 로고
    • Dehydroepiandrosterone suppresses elevated hepatic glucose-6-phosphatase mRNA level in C57BL/KsJ-db/db mice: Comparison with troglitazone
    • Aoki K., Kikuchi T., Mukasa K., Itoh S., Nakajima A., Satoh S., Okamura A., Sekihara H. Dehydroepiandrosterone suppresses elevated hepatic glucose-6-phosphatase mRNA level in C57BL/KsJ-db/db mice: comparison with troglitazone. Endocrinol. J. 47:2000;799-804.
    • (2000) Endocrinol. J. , vol.47 , pp. 799-804
    • Aoki, K.1    Kikuchi, T.2    Mukasa, K.3    Itoh, S.4    Nakajima, A.5    Satoh, S.6    Okamura, A.7    Sekihara, H.8
  • 13
    • 0026328941 scopus 로고
    • Antiobesity effects of dehydroepiandrosterone are mediated by futile substrate cycling in hepatocytes of BHE/cbd Rats
    • McIntosh M.K., Berdanier C.D. Antiobesity effects of dehydroepiandrosterone are mediated by futile substrate cycling in hepatocytes of BHE/cbd Rats. J. Nutr. 121:1991;2037-2043.
    • (1991) J. Nutr. , vol.121 , pp. 2037-2043
    • McIntosh, M.K.1    Berdanier, C.D.2
  • 16
    • 0023102652 scopus 로고
    • The effects of hyperinsulinemia on serum testosterone, progesterone, dehydroepiandrosterone sulfate, and cortisol levels in normal women and in a woman with hyperandrogenism, insulin resistance, and acanthosis nigricans
    • Nestler J.E., Clore J.N., Strauss J.F., Blackard W.G. The effects of hyperinsulinemia on serum testosterone, progesterone, dehydroepiandrosterone sulfate, and cortisol levels in normal women and in a woman with hyperandrogenism, insulin resistance, and acanthosis nigricans. J. Clin. Endocrinol. Metab. 64:1987;180-184.
    • (1987) J. Clin. Endocrinol. Metab. , vol.64 , pp. 180-184
    • Nestler, J.E.1    Clore, J.N.2    Strauss, J.F.3    Blackard, W.G.4
  • 17
    • 0028835363 scopus 로고
    • Effects of insulin reduction with benfluorex on serum dehydroepiandrosterone (DHEA), DHEA sulfate, and blood pressure in hypertensive middle-aged and elderly men
    • Nestler J.E., Beer N.A., Jakubowicz D.J., Colombo C., Beer R.M. Effects of insulin reduction with benfluorex on serum dehydroepiandrosterone (DHEA), DHEA sulfate, and blood pressure in hypertensive middle-aged and elderly men. J. Clin. Endocrinol. Metab. 80:1995;700-706.
    • (1995) J. Clin. Endocrinol. Metab. , vol.80 , pp. 700-706
    • Nestler, J.E.1    Beer, N.A.2    Jakubowicz, D.J.3    Colombo, C.4    Beer, R.M.5
  • 21
    • 0021367659 scopus 로고
    • Inhibition of 1,2-dimethylhydrazine-induced colon tumorigenesis in Balb/ c mice by dehydroepiandrosterone
    • Nyce J.W., Magee P.N., Hard G.C., Schwartz A.G. Inhibition of 1,2-dimethylhydrazine-induced colon tumorigenesis in Balb/c mice by dehydroepiandrosterone. Carcinogenesis. 5:1984;57-62.
    • (1984) Carcinogenesis , vol.5 , pp. 57-62
    • Nyce, J.W.1    Magee, P.N.2    Hard, G.C.3    Schwartz, A.G.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.