Twenty One Novel Single Nucleotide Polymorphisms (SNPs) of the CYP2A6 Gene in Japanese and Caucasians

Drug Metabolism and Pharmacokinetics

Volumn 17, Issue 5, 2002, Pages 482-487

  Kiyotani, Kazuma ^a   Fujieda, Masaki ^a   Yamazaki, Hiroshi ^a   Kamataki, Tetsuya ^a   Shimada, Tsutomu ^b   Peter Guengerich, F ^c   Parkinson, Andrew ^d   Nakagawa, Kazuko ^e   Ishizaki, Takashi ^e  

^a HOKKAIDO UNIVERSITY   (Japan)

^b OSAKA PREFECTURAL INSTITUTE OF PUBLIC HEALTH   (Japan)

^c VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d XenoTech LLC   (United States)

^e KUMAMOTO UNIVERSITY   (Japan)

Author keywords

genetic polymorphism; genotyping; intron; P450 2A6; racial difference

Indexed keywords

EID: 0041361124     PISSN: 13474367     EISSN: 18800920     Source Type: Journal    
DOI: 10.2133/dmpk.17.482     Document Type: Article

References (3)

1. Kiyotani, K., Yamazaki, H., Fujieda, M., Daigo, S., Satarug, S., Ujjin, P. and Kamataki, T.: Novel Mutations of the CYP2A6 gene in a Thai population with lowered capacity of coumarin 7-hydroxylation. Drug Metab. Pharmacokinet., 17: 161-163 (2002).
2. Loriot, M.-A., Rebuissou, S., Oscarson, M., Cenee, S., Miyamoto, M., Ariyoshi, N., Kamataki, T., Hemon, D., Beaune, P. and Stucker, I.: Genetic polymorphisms of cytochrome P4S0 2A6 in a case-control study on lung cancer in a French population. Pharmacogenetics, II: 39-44 (2001).
3. Toide, K., Takahashi, Y., Yamazaki, H., Terauchi, Y., Fujii, T., Parkinson, A. and Kamataki, T.: Hepatocyte nuclear factor-1-is a causal factor responsible for interindividual differences in the expression of UDP-glucuronosyltransferase 2B7 mRNA in human livers. Drug Metab. Dispos., 30: 613-61S (2002).