Release characteristics of polymethacrylate nanospheres containing coumarin-6

Journal of Microencapsulation

Volumn 20, Issue 5, 2003, Pages 653-659

  Eley, John G ^a   Tirumalasetty, P P ^b  

^a PALM BEACH ATLANTIC UNIVERSITY   (United States)

^b AUBURN UNIVERSITY   (United States)

Author keywords

Coumarin 6; Eudrigit ; Nanospheres; Sustained release

Indexed keywords

ANALGESIC AGENT; COUMARIN DERIVATIVE; NANOPARTICLE; POLYMER; POLYMETHACRYLIC ACID; PROTEIN S 100;

ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DIFFUSION; DRUG STABILITY; DRUG UPTAKE; IONIZATION; MICROENCAPSULATION; PARTICLE SIZE; PH; SCANNING ELECTRON MICROSCOPY; STRUCTURE ANALYSIS; SUSTAINED DRUG RELEASE; TEMPERATURE;

ANALGESICS; BIOCOMPATIBLE MATERIALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DELAYED-ACTION PREPARATIONS; DRUG COMPOUNDING; DRUG STABILITY; HYDROGEN-ION CONCENTRATION; MICROSCOPY, ELECTRON, SCANNING; MICROSPHERES; PARTICLE SIZE; POLYMERS; POLYMETHACRYLIC ACIDS; SOLUBILITY;

EID: 0041355359     PISSN: 02652048     EISSN: None     Source Type: Journal    
DOI: 10.1080/0265204031000150876     Document Type: Article

References (10)

1. Allemann, E., Gurney, R. and Doelker, E., 1992, Preparation of aqueous polymeric nanodispersions by a reversible salting-out process: influence of process parameters on particle size. International Journal of Pharmaceutics, 87, 247-253.
2. Chan, W. A., Boswell, C. D. and Zhang, Z., 2001, Comparison of the release profiles of a water soluble drug carried by Eudragit-coated capsules in different in-vitro dissolution liquids. Powder Technology, 119, 26-32.
3. Gao, Z. G., Oh, K. H. and Kim, C. K., 1998, Preparation and characterization of sustained-release microspheres of chlorpromazine. Journal of Microencapsulation, 15, 75-83.
4. Higuchi, T., 1963, Mechanism of sustained-action medication; theoretical analysis of rate and release of solid drugs dispersed in solid matrices. Journal of Pharmaceutical Science, 52, 1145-1149.
5. Jenzuin, M. R., Liebowitz, S. M., Sarabia, R. E. and McGinity, J. W., 1990, Physical and chemical factors influencing the release of drugs from acrylic resin films. Journal of Pharmaceutical Science, 79, 811-816.
6. Kawata, M., Nakamura, M., Goto, S. and Aoyama, T., 1986, Preparation and dissolution pattern of Eudragit RS microcapsules containing ketoprofen. Chemical and Pharmaceutical Bulletin, 34, 2618-2623.
7. Kim, C. K. and Yoon, Y. S., 1991, The preparation of ascorbic acid pellets using the wet pelletization process in liquid media. Drug Development and Industrial Pharmacy, 17, 581-591.
8. Lehmann, K., 1992, Fluid-bed spray coating. In Microcapsules and Nanoparticles in Medicine and Pharmacy, edited by M. Donbrow (Boca Raton: CRC Press Inc.), pp. 73-97.
9. Ndesendo, V. M. K., Meixner, W., Kaorstko-Wabnegg, B. and Kaorstko, W. B., 1996, Microencapsulation of chloroquine diphosphate by Eudragit RS 100. Journal of Microencapsulation, 13, 1-8.
10. Otsuka, M., Onoe, M. and Matsudam, Y., 1993. Hygroscopic stability and dissolution properties of spray-dried solid dispersions of furosemide with Eudragit. Journal of Pharmaceutical Science, 82, 32-38.