Effects of midazolam on equine innate immune response: A flow cytometric study

Veterinary Immunology and Immunopathology

Volumn 95, Issue 1-2, 2003, Pages 11-19

  Massoco, C ^a   Palermo Neto, J ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Flow cytometry; Horses; Macrophage; Midazolam; Neutrophil; Oxidative burst; Phagocytosis

Indexed keywords

ANXIOLYTIC AGENT; DORMIRE; HYDROCORTISONE; MIDAZOLAM;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DOSE CALCULATION; DOSE TIME EFFECT RELATION; DRUG ACTIVITY; DRUG EFFECT; DRUG EXPOSURE; ERYTHROPHAGOCYTOSIS; FEMALE; FLOW CYTOMETRY; HORSE; HYDROCORTISONE BLOOD LEVEL; IMMUNE STATUS; IMMUNE SYSTEM; IMMUNOCOMPETENT CELL; LEUKOCYTE MEMBRANE; MALE; NEUTROPHIL; NONHUMAN; PERITONEUM MACROPHAGE; RESPIRATORY BURST; SINGLE DRUG DOSE; STAPHYLOCOCCUS AUREUS;

EQUIDAE; STAPHYLOCOCCUS; STAPHYLOCOCCUS AUREUS;

EID: 0041335374     PISSN: 01652427     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-2427(03)00097-7     Document Type: Article

References (43)

1. Bass D.A., Parce J.W., Dechatelet L.R., Szejda P., Seeds M.C., Thomas M. Flow cytometric studies of oxidative produce formation by neutrophils: a graded response to membrane stimulation. J. Immunol. 130:1983;1910-1917.
2. Bassoe C.F., Laerum O.D., Solberg C.O., Haneberg B. Phagocytosis of bacteria by human leucocytes measured by flow cytometry. Proc. Soc. Exp. Biol. Med. 174:1983a;182-186.
3. Bassoe C.F., Laerum O.D., Glette F., Hopen G., Haneberg B., Solberg C.O. Simultaneous measurement of phagocytosis and phagosomal pH by flow Cytometry: role of polymorphonuclear neutrophilic leukocyte granules in phagosome acidification. Cytometry. 4:1983b;254-262.
4. Bengtsson T., Jaconi M.E.E., Gustafson M., Magnusson K.E., Theler J.M., Lew D.P., Stendhal O. Actin dynamic in human neutrophils during adhesion and phagocytosis is controlled by changes in intracellular free calcium. Eur. J. Cell. Biol. 62:1993;49-58.
5. 3H ] diazepam binding Proc. Natl. Acad. Sci. U.S.A. 74:1977;3805-3809.
6. Brandt R., Keston A.S. Synthesis of diacetyldichlorofluorescein: a stable reagent for fluorometric analysis. Anal. Biochem. 11:1965;6.
7. Canat X., Guillaumont A., Bouaboula M., Poinot-Chazel C., Derocq J.M., Carayon P., Le Fur G., Casellas P. Peripheral benzodiazepine receptor modulation with phagocyte differentiation. Biochem. Pharmacol. 46:1993;551-554.
8. Casellas P., Galiegue S., Basile A.S. Peripheral benzodiazepine receptors and mitochondrial function. Neurochem. Int. 40:2002;475-486.
9. Cavallaro S., Korneyev A., Guidotti A., Costa E. DBI-processing products, acting at the mitochondrial DBI receptor, mediate ACTH-induced steroidogenesis in rat adrenal. Proc. Natl. Acad. Sci. U.S.A. 89:1992;10598-10602.
10. Cohen M., Pickar D., Dubois M., Roth Y.F., Naber D., Bunney W.E. Jr. Surgical stress and endorphins (letter). Lancet. 1:1981;213-214.
11. Fearon D.T., Collins L.A. Increased expression of C3b receptors on polymorphonuclear leukocytes induced by chemotactic factors and purification procedures. J. Immunol. 130:1983;370-375.
12. Ferrarese C., Appolonio I., Frigo M., Perego M., Pierpaoli C., Trabucchi M., Frattola L. Characterization of peripheral benzodiazepine receptors in human blood mononuclear cells. Neuropharmacology. 29:1990;375-378.
13. Hamilton T.A., Adams D.O. Molecular mechanism of signal transduction in macrophages. Immunol. Today. 5:1987;151-158.
14. Hasui M., Hirabayashi Y., Kobayashi Y. Simultaneous measurement by flow cytometry of phagocytosis and hydrogen peroxide production of neutrophils in whole blood. J. Immunol. Methods. 117:1989;53-58.
15. Hirabayashi Y., Taniuchi S., Kobayashi Y. A quantitative assay of oxidative metabolism by neutrophils in whole blood using flow cytometry. J. Immunol. Methods. 82:1985;253-259.
16. Ishiguro K., Taft W.C., de Lorenzo R.J., Sartorelli A.C. The role of benzodiazepine receptors in the induction of differentiation of HL-60 leukemia cells by benzodiazepine and purines. J. Cell. Physiol. 131:1987;226-234.
17. James V.H.T., Horner M.W., Moss M.S., Rippon A.E. Adrenocortial function in the horse. J. Endocrinol. 48:1970;319-335.
18. Johannisson A., Gro-Ndahl G., Demmers S., Jensen-Waern M. Flow-cytometric studies on the phagocytic capacities of equine neutrophils. Acta Vet. Scand. 36:1995;553-562.
19. Lazzarini R., Malucelli B.E., Palermo-Neto J. Reduction of acute inflammation in rats by diazepam: role of peripheral benzodiazepine receptors and corticosterone. Immunopharmacol. Immunotoxicol. 23:2001;253-265.
20. Luna S.P., Massone F., Castro G.B., Fantoni D.T., Hussni C.A., Aguiar A.J. A combination of methotrimeprazine, midazolam and guaiphenesin, with and without ketamine in an anaesthetic procedure of horses. Vet. Rec. 131:1992;33-35.
21. Massoco C.O., Palermo-Neto J. Diazepam effects on peritoneal macrophage activity and corticosterone serum levels in Balb/c mice. Life Sci. 65:1999;2157-2165.
22. McEwen B.S., Biron C.A., Brunson K.W., Bullock K., Chambers W.H., Dhabhar F.S., Goldfarb R.H., Kitson R.P., Miller A.H., Spencer R.L., Weiss J.M. The role of adrenocorticoids as modulators of immune function in health and disease: neural, endocrine and immune interaction. Brain Res. Rev. 23:1997;79-133.
23. Mestre M., Carrior T., Belin C., Uzan A., Renault C., Dubroeucq M.C., Gueremy C., Doble A., Le Fur G. Electrophysiological and pharmacological evidence that peripheral type benzodiazepine receptors are coupled to calcium channels in the heart. Life Sci. 36:1985;391-400.
24. Nathan C.F. Neutrophil activation on biological surfaces: massive secretion of hydrogen peroxide in response to products of macrophage and lymphocytes. J. Clin. Invest. 80:1987;1550-1560.
25. Noel G.L., Suh H.K., Stone J.C., Frantz A.G. Human prolactin and growth hormone release during surgery and other conditions of stress. J. Clin. Endocrinol. Metab. 35:1972;840-851.
26. Okun F., Weizman R., Katz Y., Bomzon A., Youdim M.B.H., Gavish M. Increase in central and peripheral benzodiazepine receptors following surgery. Brain Res. 458:1988;31-36.
27. Papadopoulos V. Peripheral-type benzodiazepine/diazepam binding inhibitor receptor: biological role in steroidogenic cell function. Endocr. Rev. 14:1993;222-240.
28. Raidal S.L., Bailey G.D., Love D.N. Flow cytometric determination of oxidative burst activity of equine peripheral blood and bronchoalveolar lavage-derived leukocytes. Vet. J. 156:1998;117-126.
29. Rees, R.C., Parry, H., 1991. Macrophages in tumor immunity. In: Lewis, C.E., McGee, J.O'D. (Eds.), The Macrophage. IRL Press, New York, pp. 3-423.
30. Righi D.A., Pinheiro S.R., Guerra J.L., Palermo-Neto J. Diazepam effects on Mycobacterium bovis-induced infection in hamsters. Braz. J. Med. Biol. Res. 32:1999;1145-1153.
31. Rocca P., Bellone G., Benna P., Bergamasco B., Ravizza L., Ferrero P. Peripheral-type benzodiazepine receptors and diazepam binding inhibitor-like immunoreactivity distribution in human peripheral blood mononuclear cells. Immunopharmacology. 25:1993;163-178.
32. 2 release from human granulocytes during phagocytosis. J. Clin. Invest. 55:1975;945.
33. Rothe G., Valet G. Flow cytometric analysis of respiratory burst activity in phagocytes with hidroethidine and 2′,7′ -dichlorofluorescein. J. Leuk. Biol. 47:1990;440-448.
34. Ruiz I., Offermanns J., Lanctot K.L., Busto U. Comparative study on benzodiazepine use in Canada and Chile. J. Clin. Pharmacol. 33:1993;124-125.
35. Saad A.M., Hageltorn M. Flow cytometric characterization of bovine blood neutrophil Phagocytosis of fluorescent bacteria and zymosan particles. Acta Vet. Scand. 26:1985;289-307.
36. Schulumpf M., Lichtensteiger W., Loveren H. Impaired host resistance to Trichinella spiralis as a consequence of prenatal treatment of rats with diazepam. Toxicology. 94:1994;223-229.
37. Speert, D.P., 1991. Macrophages in bacterial infection. In: Lewis, C.E., McGee, J.O'D. (Eds.), The Macrophage. IRL Press, New York, pp. 3-423.
38. Taupin V., Jayais P., Descamps-Latscha B., Cazala J.B., Barrier G., Bach J.F., Zavala F. Benzodiazepine anesthesia in humans modulates the interleukin-1 beta, tumor necrosis factor-alpha and interleukin-6 responses of blood monocytes. J. Neuroimmunomodul. 35:1991;13-19.
39. Torres S.R., Fröde T.S., Nardi G.M., Vita N., Reeb R., Ferrara P., Ribeiro-do-Vale R.M., Farges R.C. Anti-inflammatory effects of peripheral benzodiazepine receptor ligands in two mouse models of inflammation. Eur. J. Pharmacol. 408:2000;199-211.
40. Zavala F., Lenfant M. Interactions of benzodiazepines with mouse macrophages. Eur. J. Pharmacol. 106:1984;561-566.
41. Zavala F., Lenfant M. Peripheral benzodiazepine enhance the respiratory burst of macrophage-like P388D1 cells stimulated by arachidonic acid. Int. Immunopharmacol. 9:1987;269-274. [Eur. J. Pharmacol. 106, 561-566].
42. Zavala F., Taupin V., Descamps-Latscha B. In vivo treatment with benzodiazepine inhibits murine phagocyte oxidative metabolism and production of interleukin-1, tumor necrosis factor and interleukin-6. J. Pharmacol. Exp. Ther. 255:1990;442-450.
43. Zavala F., Masson A., Brys L., de Baetselier P., Descamps-Latscha B. A monoclonal antibody against peripheral benzodiazepine receptor activates the human neutrophil NADPH-oxidase. Biochem. Biophys. Res. Commun. 176:1991;1577-1583.