Experimental evolution yields hundreds of mutations in a functional viral genome

Journal of Molecular Evolution

Volumn 57, Issue 3, 2003, Pages 241-248

  Bull, J J ^a   Badgett, M R ^a,b   Rokyta, D ^a,c   Molineux, I J ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^b APPLIED BIOSYSTEMS   (United States)

^c UNIVERSITY OF IDAHO   (United States)

Author keywords

Adaptation; Experimental evolution; Fitness; Genome; Microbial evolution

Indexed keywords

AMINO ACID SUBSTITUTION; ARTICLE; BACTERIOPHAGE T7; BOTTLENECK POPULATION; ESSENTIAL GENE; EVOLUTION; GENOMIC FRAGMENT; MISSENSE MUTATION; MUTATION; NONHUMAN; POINT MUTATION; VIRUS GENOME;

BACTERIOPHAGE T7; DIRECTED MOLECULAR EVOLUTION; GENOME, VIRAL; MODELS, GENETIC; MUTATION;

PROKARYOTA;

EID: 0041331688     PISSN: 00222844     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00239-003-2470-1     Document Type: Article

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