Control of respiration by nitric oxide in Keilin-Hartree particles, mitochondria and SH-SY5Y neuroblastoma cells

Cellular and Molecular Life Sciences

Volumn 60, Issue 8, 2003, Pages 1752-1759

  Mastronicola, D ^a   Genova, M L ^b   Arese, M ^c   Barone, M C ^c   Giuffre A ^c   Bianchi, C ^b   Brunori, M ^c   Lenaz, G ^b   Sarti, P ^c  

^a REGINA ELENA NATIONAL CANCER INSTITUTE   (Italy)

^b UNIVERSITY OF BOLOGNA   (Italy)

^c SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

Control of respiration; Haemoprotein; NO scavenging; Reaction mechanism; Tumour cells

Indexed keywords

ASCORBIC ACID; CYTOCHROME C OXIDASE; GLUTAMIC ACID; MALIC ACID; N,N,N',N' TETRAMETHYL 1,4 PHENYLENEDIAMINE; NITRIC OXIDE;

ANIMAL CELL; ARTICLE; CELL ORGANELLE; CELL RESPIRATION; ELECTRON TRANSPORT; ENZYME INHIBITION; HUMAN; HUMAN CELL; KEILIN HARTREE PARTICLE; KINETICS; MITOCHONDRION; NEUROBLASTOMA CELL; NONHUMAN; PHOTOSENSITIVITY; REGULATORY MECHANISM;

ANIMALS; CATTLE; CELL RESPIRATION; ELECTRON TRANSPORT COMPLEX IV; HUMANS; MALE; MICE; MICE, INBRED BALB C; MITOCHONDRIA, LIVER; MODELS, BIOLOGICAL; MYOCARDIUM; NEUROBLASTOMA; NITRIC OXIDE; POLAROGRAPHY; RATS; RATS, WISTAR; TUMOR CELLS, CULTURED;

ANIMALIA;

EID: 0041328229     PISSN: 1420682X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00018-003-3127-3     Document Type: Article

References (37)

1. Cleeter M. W. J., Cooper J. M., Darley-Usmar V. M., Moncada S. and Schapira A. H. V. (1994) Reversible inhibition of cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, by nitric oxide. FEBS Lett. 345: 50-54
2. Schweizer M. and Richter C. (1994) NO potently and reversibly de-energizes mitochondria at low oxygen tension. Biochem. Biophys. Res. Commun. 204: 169-175
3. Brown G. C. and Cooper C. E. (1994) Nanomolar concentration of nitric oxide reversibly inhibit synaptosomal cytochrome oxidase respiration, by competing with oxygen at cytochrome oxidase. FEBS Lett. 356: 295-298
4. Heales J. R., Bolaños J. P., Stewart V. C., Brookes P. S., Land J. M. and Clark J. B. (1999) NO, mitochondria and neurological disease. Biochim. Biophys. Acta 1410: 215-228
5. Wolin M. S., Xie Y. W. and Hintze T. H. (1999) Nitric oxide as a regulator of tissue oxygen consumption. Curr. Opin. Nephrol. Hypertens 8: 97-103
6. Nisoli E., Clementi E., Paolucci C., Cozzi V., Tonello C., Sciorati C. et al. (2003) Mitochondrial biogenesis in mammals: the role of endogenous nitric oxide. Science 299: 896-899
7. Stumpe T, Decking U. K. M. and Schrader J. (2001) Nitric oxide reduces energy supply by direct action on the respiratory chain in isolated cardiomyocytes. Am. J. Physiol Heart Circ. Physiol. 280: H2350-H2356
8. Brown G. C. (2003) NO says yes to mitochondria. Science 299: 838-839
9. Moncada S. and Erusalimsky J. D. (2002) Does nitric oxide modulate mitochondrial energy generation and apoptosis? Nat. Rev. Mol. Cell. Biol. 3: 214-220
10. Cooper C. E. (2002) Nitric oxide and cytochrome oxidase: substrate, inhibitor or effector? Trends. Biochem. Sci. 27: 33-39
11. Sarti P., Giuffrè A, Barone M. C., Forte E., Mastronicola D. and Brunori M. (2003) Nitric oxide and cytochrome oxidase: reaction mechanisms from the enzyme to the cell. Free Rad. Biol. Med. 34: 509-520
12. Brown G. C. (2001) Regulation of mitochondrial respiration by nitric oxide inhibition of cytochrome c oxidase. Biochim. Biophys. Acta 1504: 46-57
13. Torres J., Darley-Usmar V. M. and Wilson M. T. (1995) Inhibition of cytochrome c oxidase in turnover by nitric oxide: mechanism and implications for control of respiration. Biochem. J. 312: 169-173
14. Giuffrè A., Sarti P., D'Itri E., Buse G., Soulimane T. and Brunori M. (1996) On the mechanism of inhibition of cytochrome c oxidase by nitric oxide. J. Biol. Chem. 271: 33404-33408
15. Cooper C. E., Torres J., Sharpe M. A. and Wilson M. T. (1997) Nitric oxide ejects electrons from the binuclear center of cytochrome c oxidase by reacting with oxidized copper: a general mechanism for the interaction of copper proteins with nitric oxide? FEBS Lett. 414: 281-284
16. Giuffrè A., Barone M. C., Mastronicola D, D'Itri E., Sarti P. and Brunori M. (2000) Reaction of nitric oxide with the turnover intermediates of cytochrome c oxidase: reaction pathway and functional effects. Biochemistry 39: 15446-15453
17. Blackmore R. S., Greenwood C. and Gibson Q. H. (1991) Studies of the primary oxygen intermediate in the reaction of fully reduced cytochrome oxidase. J. Biol. Chem. 266: 19245-19249
18. Sarti P., Giuffrè A., Forte E., Mastronicola D., Barone M. C. and Brunori M. (2000) Nitric oxide and cytochrome c oxidase: mechanisms of inhibition and NO degradation. Biochem. Biophys. Res. Commun. 274: 183-187
19. Boelens R., Wever R., Van Gelder B. F. and Rademaker H. (1983) An EPR study of the photodissociation reactions of oxidised cytochrome c oxidase-nitric oxide complexes. Biochim. Biophys. Acta. 724: 176-183
20. Antonini E. and Brunori M. (1971) The derivatives of ferrous hemoglobin and myoglobin. In: Hemoglobin and Myoglobin in Their Reactions with ligands, pp. 29-31, Neuberger A. and Tatum E.L. (eds), North-Holland, Amsterdam
21. Sarti P., Lendaro E., Ippoliti R., Bellelli A., Benedetti P. A. and Brunori M. (1999) Modulation of mitochondrial respiration by nitric oxide: investigation by single cell fluorescence microscopy. FASEB J. 13: 191-197
22. Brunori M., Giuffrè A., Sarti P., Stubauer G. and Wilson M. T. (1999) Nitric oxide and cellular respiration. Cell. Mol. Life Sci. 56: 549-557
23. Soulimane T. and Buse G. (1995) Integral cytochrome-c oxidase: preparation and progress towards a three-dimensional crystallization. Eur. J. Biochem 227: 588-595
24. 3. Biochim. Biophys. Acta 118: 36-46
25. Kun E., Kirsten E. and Piper W. N. (1979) Stabilization of mitochondrial functions with digitonin. Methods Enzymol. 55: 115-118
26. Chance B. and Williams G. R. (1956) The respiratory chain and oxidative phosphorylation. Adv. Enzymol. 17: 65-134
27. Borutaitè V. and Brown G. C. (1996) Rapid reduction of nitric oxide by mitochondria, and reversible inhibition of mitochondrial respiration by nitric oxide. Biochem. J. 315: 295-299
28. Giulivi C. (2003) Characterization and function of mitochondrial nitric-oxide synthase. Free Rad. Biol. Med. 34: 397-408
29. Shiva S., Brookes P. S., Patel R. P., Anderson P. G. and Darley-Usmar V. (2001) Nitric oxide partitioning into mitochondrial membranes and the control of respiration at cytochrome c oxidase. Proc. Natl. Acad. Sci. USA 98: 7212-7217
30. 1 complex. J. Biol. Chem. 259: 6318-6326
31. Giulivi C. (1998) Functional implications of nitric oxide pro-duced in mitochondrial metabolism. Biochem. J. 332: 673-679
32. Pearce L. L., Kanai A. J., Birder L. A., Pitt B. R. and Peterson J. (2002) The catabolic fate of nitric oxide: the nitric oxide oxidase and peroxynitrite reductase activities of cytochrome oxidase. J. Biol. Chem. 277: 13556-13562
33. Takehara Y., Kanno T., Yoshioka T., Inoue M. and Utsumi K. (1995) Oxygen-dependent regulation of mitochondrial energy metabolism by nitric oxide. Arch. Biochem. Biophys. 323: 27-32
34. Wikström M., Krab K. and Saraste M. (1981) Kinetics and catalytic mechanism. In: Cytochrome Oxidase: a Synthesis, pp. 121-123, Academic Press, London
35. Ventura B., Genova M. L., Bovina C., Formiggini G. and Lenaz G. (2002) Control of oxidative phosphorylation by complex I in rat liver mitochondria: implications for aging. Biochim. Biophys. Acta 1553: 249-260
36. Ghafourifar P., Schenk U., Klein S. D. and Richter C. (1999) Mitochondrial nitric-oxide synthase stimulation causes cy-tochrome c release from isolated mitochondria: evidence for intramitochondrial peroxynitrite formation. J. Biol. Chem. 274: 31185-31188
37. Giuffrè A., Barone M. C., Brunori M., D'Itri E., Ludwig B., Malatesta F. et al. (2002) Nitric oxide reacts with the single-electron reduced active site of cytochrome c oxidase. J. Biol. Chem. 277: 22402-22406