Epidural clonidine suppresses the baroreceptor-sympathetic response depending on isoflurane concentrations in cats

Anesthesia and Analgesia

Volumn 97, Issue 3, 2003, Pages 748-754

  Ikeda, Yoshikazu ^a   Nishikawa, Kiyonobu ^a   Ohashi, Kenji ^b   Mori, Takashi ^a   Asada, Akira ^a  

^a OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b HOSHIGAOKA KOSEINENKIN HOSPITAL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CLONIDINE; ISOFLURANE; LIDOCAINE; NITROPRUSSIDE SODIUM; PHENYLEPHRINE;

ADRENERGIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; BRADYCARDIA; CARDIAC SYMPATHETIC NERVE ACTIVITY; CAT; CONTROLLED STUDY; HEART RATE; HYPOTENSION; MEAN ARTERIAL PRESSURE; MINIMUM LUNG ALVEOLUS CONCENTRATION; NERVE CONDUCTION; NONHUMAN; PRESSOR RESPONSE; PRESSORECEPTOR REFLEX; PRIORITY JOURNAL; REVIEW; SYMPATHETIC REFLEX;

EID: 0041327912     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1213/01.ANE.0000075841.37183.A4     Document Type: Review

References (36)

1. De Kock M, Gautier P, Pavlopoulou A, et al. Epidural clonidine or bupivacaine as the sole analgesic agent during and after abdominal surgery: a comparative study. Anesthesiology 1999;90:1354-62.
2. De Kock M, Wiederkher P, Laghmiche A, Scholtes JL. Epidural clonidine used as the sole analgesic agent during and after abdominal surgery. Anesthesiology 1997;86:285-92.
3. Samso E, Valles J, Pol O, et al. Comparative assessment of the anaesthetic and analgesic effects of intramuscular and epidural clonidine in humans. Can J Anaesth 1996;43:1195-202.
4. Motsch J, Graber E, Ludwig K. Addition of clonidine enhances postoperative analgesia from epidural morphine: a double-blind study. Anesthesiology 1990;73:1067-73.
5. Ghignone M, Calvillo O, Quintin L, et al. Haemodynamic effects of clonidine injected epidurally in halothane-anaesthetized dogs. Can J Anaesth 1987;34:46-50.
6. Ohashi K, Nishikawa K, Hatano M, et al. Dose-related attenuation of cardiac sympathetic nerve activity and intracardiac conduction with thoracic epidural clonidine in α-chloralose-anesthetized cats. Osaka City Med J 2002;48:45-58.
7. Nishikawa K, Yabe M, Mori T, et al. The effects of dobutamine and phenylephrine on atrioventricular conduction during combined use of halothane and thoracic epidural lidocaine. Anesth Analg 1996;82:551-7.
8. Loick HM, Schmidt C, Van Aken H, et al. High thoracic epidural anesthesia, but not clonidine, attenuates the perioperative stress response via sympatholysis and reduces the release of troponin T in patients undergoing coronary artery bypass grafting. Anesth Analg 1999;88:701-9.
9. Myles PS, Hunt JO, Holdgaard HO, et al. Clonidine and cardiac surgery: haemodynamic and metabolic effects, myocardial ischemia and recovery. Anaesth Intensive Care 1999;27:137-47.
10. Saeki Y, Hasegawa Y, Shibamoto T, et al. The effects of sevoflurane, enflurane, and isoflurane on baroreceptor-sympathetic reflex in rabbits. Anesth Analg 1996;82:342-8.
11. Takeshima R, Dohi S. Circulatory responses to baroreflexes, Valsalva maneuver, coughing, swallowing, and nasal stimulation during acute cardiac sympathectomy by epidural blockade in awake humans. Anesthesiology 1985;63:500-8.
12. Yoneda I, Nishizawa M, Benson KT, et al. Attenuation of arterial baroreflex control of renal sympathetic nerve activity during lidocaine infusion in alpha-chloralose-anesthetized dogs. Acta Anaesthesiol Scand 1994;38:70-4.
13. Dohi S, Tsuchida H, Mayumi T. Baroreflex control of heart rate during cardiac sympathectomy by epidural anesthesia in lightly anesthetized humans. Anesth Analg 1983;62:815-20.
14. Goertz A, Heinrich H, Seeling W. Baroreflex control of heart rate during high thoracic epidural anaesthesia: a randomized clinical trial on anaesthetised humans. Anaesthesia 1992;47:984-7.
15. Godwin SJ, Tortelli CF, Parkin ML, Head GA. Comparison of the baroreceptor-heart rate reflex effects of moxonidine, rilmenidine and clonidine in conscious rabbits. J Auton Nerv Sys 1998;72:195-204.
16. Fischetti F, Fabris B, Calci M, et al. Effects of central alpha 2-adrenergic agonists on systemic haemodynamics and on baroreceptor reflex sensitivity in spontaneously hypertensive rats. Boll Soc Ital Biol Sper 1994;70:279-86.
17. Hayashi J, Takeda K, Kuwabara T, et al. Clonidine improves central attenuation of the baroreflex in spontaneously hypertensive rats. Jpn Heart J 1993;34:333-9.
18. Watkins L, Maixner W. Hypotensive effect of clonidine is not mediated by enhanced baroreflex gain in rats. J Cardiovasc Pharmacol 1993;21:264-71.
19. Muzi M, Goff DR, Kampine JP, et al. Clonidine reduces sympathetic activity but maintains baroreflex responses in normotensive humans. Anesthesiology 1992;77:864-71.
20. Parlow JL, Begou G, Sagnard P, et al. Cardiac baroreflex during the postoperative period in patients with hypertension: effect of clonidine. Anesthesiology 1999;90:681-92.
21. Watanabe Y, Iida H, Tanabe K, et al. Clonidine premedication modifies response to adrenoceptor agonists and baroreflex sensitivity. Can J Anaesth 1998;45:1084-90.
22. Eisenach JC, Tong C, Limauro D. Intrathecal clonidine and the response to hemorrhage. Anesthesiology 1992;77:522-8.
23. Baron JF, Jacolot AD, Edouard A, et al. Influence of venous return on baroreflex control of heart rate during lumbar epidural anesthesia in humans. Anesthesiology 1986;64:188-93.
24. 2-adrenergic agonists. Anesthesiology 1991;74:766-71.
25. Kirno K, Lundin S, Elam M. Epidural clonidine depresses sympathetic nerve activity in humans by a supraspinal mechanism. Anesthesiology 1993;78:1021-7.
26. Jarrot B, Conway EL, Maccarrone C, et al. Clonidine: understanding its disposition, sites and mechanism of action. Clin Exp Pharmacol Physiol 1987;14:471-9.
27. Nishikawa K, Terai T, Morimoto O, et al. Effects of intravenous lidocaine on cardiac sympathetic nerve activity and A-V conduction in halothane-anesthetized cats. Acta Anaesthesiol Scand 1994;38:115-20.
28. A receptors modulate the capacity of isoflurane to produce immobility. Anesth Analg 2001;92:1585-9.
29. Muzi M, Ebert TJ. A comparison of baroreflex sensitivity during isoflurane and desflurane anesthesia in humans. Anesthesiology 1995;82:919-25.
30. De Kock M, Martin N, Scholtes JL. Central effects of epidural and intravenous clonidine in patients anesthetized with enflurane/nitrous oxide. Anesthesiology 1992;77:457-62.
31. Tanaka M, Nishikawa T. Effects of clonidine premedication on the pressor response to alpha-adrenergic agonists. Br J Anaesth 1995;75:593-7.
32. Marano G, Grigioni M, Tiburzi F, et al. Effects of isoflurane on cardiovascular system and sympathovagal balance in New Zealand white rabbits. J Cardiovasc Pharmacol 1996;28:513-8.
33. Picker O, Scheeren TW, Arndt JO. Inhalation anaesthetics increase heart rate by decreasing cardiac vagal activity in dogs. Br J Anaesth 2001;87:748-54.
34. Taniguchi M, Kasaba T, Takasaki M. Epidural anesthesia enhances sympathetic nerve activity in the unanesthetized segments in cats. Anesth Analg 1997;84:391-7.
35. Ohashi K, Nishikawa K, Hatano M, et al. Epidural clonidine suppressed sympathetic nerve activity by spinal mechanism [abstract]. Anesthesiology 2000;93:A666.
36. Mori T, Nishikawa K, Terai T, et al. The effects of epidural morphine on cardiac and renal sympathetic nerve activity in α-chloralose-anesthetized cats. Anesthesiology 1998;88:1558-65.