Lack of association between serotonin 5-HT1B receptor gene polymorphism and suicidal behavior

American Journal of Medical Genetics - Neuropsychiatric Genetics

Volumn 116 B, Issue 1, 2003, Pages 69-71

  Rujescu, Dan ^a   Giegling, Ina ^a   Sato, Tetsuya ^a   Möller, Hans Jürgen ^a  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

Author keywords

5 HT1B; Gene; Polymorphism; Serotonin; Suicide

Indexed keywords

SEROTONIN 1B RECEPTOR;

ADOPTION; ADULT; AGED; AGGRESSION; ALLELE; ARTICLE; BIPOLAR DISORDER; BORDERLINE STATE; CONTROLLED STUDY; DNA POLYMORPHISM; FAMILY STUDY; FEMALE; GENE; GENETIC SUSCEPTIBILITY; GENOTYPE; GERMANY; HUMAN; HUMAN CELL; IMPULSIVENESS; KNOCKOUT MOUSE; MAJOR CLINICAL STUDY; MAJOR DEPRESSION; MALE; MENTAL DISEASE; PRIORITY JOURNAL; RELATIVE; SCHIZOPHRENIA; SEROTONIN 1B RECEPTOR GENE; SEX DIFFERENCE; SUICIDAL BEHAVIOR; SUICIDE; SUICIDE ATTEMPT; TWINS;

EID: 0041324743     PISSN: 15524841     EISSN: 1552485X     Source Type: Journal    
DOI: 10.1002/ajmg.b.10732     Document Type: Article

References (11)

1. Brunner D, Hen R. 1997. Insights into the neurobiology of impulsive behavior from serotonin receptor knockout mice. Ann NY Acad Sci 836:81-105.
2. First MB, Spitzer RL, Gibbon M, Williams JBW. 1997. Structured clinical interview for DSM-IV Axis I and II disorders. Washington, DC: American Psychiatric Press.
3. Huang Y, Grailhe R, Arango V, Hen R, Mann JJ. 1999. Relationship of psychopathology to the human serotonin 1B genotype and receptor binding kinetics in postmortem brain tissue. Neuropharmacology 21:238-246.
4. Lappalainen J, Dean M, Charbonneau L, Virkkunen M, Linnoila M, Goldman D. 1995. Mapping of the serotonin 5-HT1Dβ autoreceptor gene on chromosome 6 and direct analysis for sequence variants. Am J Med Genet 60:157-161.
5. Mann JJ. 1998. The neurobiology of suicide. Nat Med 4:25-30.
6. McGuffin P, Marusic A, Farmer A. 2001. What can psychiatric genetics offer suicidology? Crisis 22:61-65.
7. Moret C, Briley M. 2000. The possible role of 5-HT 1B/D receptors in psychiatric disorders and their potential as a target for therapy. Eur J Pharmacol 404:1-12.
8. Nishiguchi N, Shirakawa O, Ono H, Nishimura A, Nushida H, Ueno Y, Maeda K. 2001. No evidence of an association between 5HT1B receptor gene polymorphism and suicide victims in a Japanese population. Am J Med Genet 105:343-345.
9. Rice JP, Reich T, Bucholz KK, Neuman RJ, Fishman R, Rochberg N. 1995. Comparison of direct interview and family history diagnoses of alcohol dependence. Alcohol Clin Exp Res 19:1018-1023.
10. Sidenberg DG, Basset AS, Demchyshyn L, Niznik HB, Macciardi F, Kamble AB, Kennedy JL. 1993. New polymorphism for the human serotonin 1D receptor variants (5-HT1Dβ) not linked to schizophrenia in five Canadian pedigrees. Hum Hered 43:315-318.
11. Wittchen HU, Zaudig M, Fydrich T. 1997. Strukturiertes Klinisches Interview für DSM-IV, Achse I und II. Goettingen: Hogrefe.