Construction of reporter yeasts for mouse aryl hydrocarbon receptor ligand activity

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 540, Issue 1, 2003, Pages 99-105

  Kawanishi, Masanobu ^a   Sakamoto, Michiyo ^a   Ito, Akihide ^b   Kishi, Kyoko ^a   Yagi, Takashi ^a  

^a Osaka Prefecture University   (Japan)

^b MITSUI ENGINEERING AND SHIPBUILDING CO LTD   (Japan)

Author keywords

AhR ligand; Arnt; Dioxin; Indirubin

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; 3 METHYLCHOLANTHRENE; AROMATIC HYDROCARBON RECEPTOR; AROMATIC HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR PROTEIN; BENZO[A]PYRENE; BETA GALACTOSIDASE; BETA NAPHTHOFLAVONE; CARRIER PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVITY; EXPRESSION VECTOR; GENE CONSTRUCT; HUMAN; LIGAND BINDING; MOUSE; NONHUMAN; PLASMID; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPORTER GENE; SACCHAROMYCES CEREVISIAE; SPECIES DIFFERENCE; YEAST;

ACRONICTA LEPORINA; SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

EID: 0041324597     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1383-5718(03)00174-8     Document Type: Article

References (28)

1. Pohjanvirta R., Tuomisto J. Short-term toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in laboratory animals: effects, mechanisms, and animal models. Pharmacol. Rev. 46:1994;483-549.
2. Gonzalez F.J., Fernandez-Salguero P. The aryl hydrocarbon receptor: studies using the AhR-null mice. Drug Metab. Dispos. 12:1998;1194-1198.
3. Okey A.B., Riddick D.S., Harper P.A. Molecular biology of the aromatic hydrocarbon (dioxin) receptor. Trends Pharmacol. Sci. 15:1994;226-232.
4. Hoffman E.C., Reyes H., Chu F.-F., Sander F., Conley L.H., Brooks B.A., Hankinsin O. Cloning of a factor required for activity of the Ah (dioxin) receptor. Science. 252:1991;954-958.
5. Fujisawa-Sehara A., Sogawa K., Yamane M., Fujii-Kuriyama Y. Characterization of xenobiotic responsive elements upstream from the drug-metabolizing cytochrome P-450c gene: a similarity to glucocorticoid regulatory elements. Nucleic Acid Res. 15:1987;4179-4191.
6. Fujisawa-Sehara A., Yamane M., Fujii-Kuriyama Y. A DNA-binding factor specific for xenobiotic responsive elements of P-450c gene exists as a cryptic form in cytoplasm: its possible translocation to nucleus. Proc. Natl. Acad. Sci. U.S.A. 85:1988;5859-5863.
7. Hapgood J., Cuthill S., Denis M., Poellinger L., Gustafsson J.-A. Specific protein-DNA interactions at a xenobiotic-responsive element: copurification of dioxin receptor and DNA-binding activity. Proc. Natl. Acad. Sci. U.S.A. 86:1988;60-64.
8. Reyes H., Reisz-Porszasz S., Hankinson O. Identification of the Ah receptor nuclear translocator protein (Arnt) as a component of the DNA binding form of the Ah receptor. Science. 256:1992;1193-1195.
9. Whitelaw M., Pongratz I., Wilhelmsson A., Gustafason J.-A., Poellinger L. Ligand-dependent recruitment of the Arnt coregulator determines DNA recognition by the dioxin receptor. Mol. Cell. Biol. 13:1993;2504-2514.
10. Matsushita N., Sogawa K., Ema M., Yoshida A., Fujii-Kuriyama Y. A factor binding to the xenobiotic responsive element (XRE) of P-4501A1 gene consists of at least two helix-loop-helix proteins, Ah receptor and Arnt. J. Biol. Chem. 268:1993;21002-21006.
11. Garrison P.M., Tullis K., Aarts J.M., Brouwer A., Giesy J.P., Denison M.S. Species-specific recombinant cell lines as bioassay systems for the detection of 2,3,7,8-tetrachlorodibenzo-p-dioxin-like chemicals. Fundam. Appl. Toxicol. 30:1996;194-203.
12. Willey J.J., Stripp B.R., Baggs R.B., Gasiewicz T.A. Aryl hydrocarbon receptor activation in genital tubercle, palate, and other embryonic tissues in 2,3,7,8-tetrachlorodibenzo-p-dioxin-responsive lacZ mice. Toxicol. Appl. Pharmacol. 151:1998;33-44.
13. Miller C.A. III Expression of the human aryl hydrocarbon receptor complex in yeast. Activation of transcription by indole compounds. J. Biol. Chem. 272:1997;32824-32829.
14. Miller C.A. III, Martinat M.A., Hyman L.E. Assessment of aryl hydrocarbon receptor complex interactions using pBEVY plasmids: expression vectors with bi-directional promoters for use in Saccharomyces cerevisiae. Nucleic Acids Res. 26:1998;3577-3583.
15. Miller C.A. III A human aryl hydrocarbon receptor signaling pathway constructed in yeast displays additive responses to ligand mixtures. Toxicol. Appl. Pharmacol. 160:1998;297-303.
16. Takamura-Enya T., Watanabe T., Tada A., Hirayama T., Nukaya H., Sugimura T., Wakabayashi K. Identification of a new mutagenic polychlorinated biphenyl derivative in the Waka River, Wakayama, Japan, showing activation of an aryl hydrocarbon receptor-dependent transcription. Chem. Res. Toxicol. 15:2002;419-425.
17. Poland A., Knutson J.C. 2,3,7,8-Tetrachlorodibenzo-p-dioxin and related halogenated aromatic hydrocarbons: examination of the mechanism of toxicity. Annu. Rev. Pharmacol. Toxicol. 22:1982;517-554.
18. Ema M., Ohe N., Suzuki M., Mimura J., Sogawa K., Ikawa S., Fujii-Kuriyama Y. Dioxin binding activities of polymorphic forms of mouse and human arylhydrocarbon receptors. J. Biol. Chem. 269:1994;27337-27343.
19. Pohjanvirta R., Wong J.M., Li W., Harper P.A., Tuomisto J., Okey A.B. Point mutation in intron sequence causes altered carboxyl-terminal structure in the aryl hydrocarbon receptor of the most 2,3,7,8-tetrachlorodibenzo-p-dioxin-resistant rat strain. Mol. Pharmacol. 54:1998;86-93.
20. Harper P.A., Golas C.L., Okey A.B. Characterization of the Ah receptor and aryl hydrocarbon hydroxylase induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin and benz[a]anthracene in the human A431 squamous cell carcinoma line. Cancer Res. 48:1988;2388-2395.
21. Dolwick K.M., Schmidt J.V., Carver L.A., Swanson H.I., Bradfield C.A. Cloning and expression of a human Ah receptor cDNA. Mol. Pharmacol. 44:1993;911-917.
22. Burbach K.M., Poland A., Bradfield C.A. Cloning of the Ah-receptor cDNA reveals a distinctive ligand-activated transcription factor. Proc. Natl. Acad. Sci. U.S.A. 89:1992;8185-8189.
23. Hoffman E.C., Reyes H., Chu F.F., Sander F., Conley L.H., Brooks B.A., Hankinson O. Cloning of a factor required for activity of the Ah (dioxin) receptor. Science. 252:1991;954-958.
24. Ema M., Sogawa K., Watanabe N., Chujoh Y., Matsushita N., Gotoh O., Funae Y., Fujii-Kuriyama Y. cDNA cloning and structure of mouse putative Ah receptor. Biochem. Biophys. Res. Commun. 184:1992;246-253.
25. Li H., Dong L., Whitlock J.P. Jr. Transcriptional activation function of the mouse Ah receptor nuclear translocator. J. Biol. Chem. 269:1994;28098-28105.
26. Adachi J., Mori Y., Matsui S., Takigami H., Fujino J., Kitagawa H., Miller C.A. III, Kato T., Saeki K., Matsuda T. Indirubin and indigo are potent aryl hydrocarbon receptor ligands present in human urine. J. Biol. Chem. 276:2001;31475-31478.
27. Korkalainen M., Tuomisto J., Pohjanvirta R. The AH receptor of the most dioxin-sensitive species, guinea pig, is highly homologous to the human AH receptor. Biochem. Biophys. Res. Commun. 285:2001;1121-1129.
28. N. Ohe, Mesocricetus auratus Ahr mRNA for arylhydrocarbon receptor, complete cds (1999), GenBank accession number: AB033505.