Clinical significance of AIB1 expression in human breast cancer

Breast Cancer Research and Treatment

Volumn 80, Issue 3, 2003, Pages 339-345

  Iwase, Hirotaka ^a   Omoto, Y ^a   Toyama, T ^a   Yamashita, H ^a   Hara, Y ^a   Sugiura, H ^a   Zhang, Z ^a  

^a NAGOYA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCES   (Japan)

Author keywords

AIB1; Breast cancer; Estrogen receptor; Gene amplification

Indexed keywords

AIB1 POLYPEPTIDE; ANTINEOPLASTIC AGENT; COMPLEMENTARY DNA; CYCLOPHOSPHAMIDE; DNA; ESTROGEN RECEPTOR ALPHA; FLUOROURACIL; METHOTREXATE; POLYPEPTIDE; STEROID RECEPTOR COACTIVATOR 1; TAMOXIFEN; UNCLASSIFIED DRUG;

ADULT; AGED; AIB1 GENE; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CANCER COMBINATION CHEMOTHERAPY; CANCER HORMONE THERAPY; CANCER SURGERY; CELL STRAIN MCF 7; DNA BINDING; FEMALE; GENE; GENE AMPLIFICATION; GENE EXPRESSION; GENETIC TRANSCRIPTION; HORMONE RECEPTOR INTERACTION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SOUTHERN BLOTTING;

ADULT; AGED; AGED, 80 AND OVER; ANTINEOPLASTIC AGENTS, HORMONAL; BLOTTING, SOUTHERN; BREAST NEOPLASMS; ESTROGEN RECEPTOR ALPHA; FEMALE; GENE AMPLIFICATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOHISTOCHEMISTRY; MIDDLE AGED; RECEPTORS, ESTROGEN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 0041322740     PISSN: 01676806     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1024916126532     Document Type: Article

References (15)

1. Iwase H, Kobayashi S: Alterations and polymorphisms of the estrogen receptor gene in breast cancer. Breast Cancer 4: 57-66, 1997
2. Guan XY, Xu J, Anzick SL, Zhang H, Trent JM, Meltzer PS: Hybrid selection of transcribed sequences from micro-dissected DNA: isolation of genes within amplified region at 20q11-q13.2 in breast cancer. Cancer Res 56: 3446-3450, 1996
3. Loe C, Chen JD: The SRC family of nuclear receptor coactivators. Gene 245: 1-11, 2000
4. Rey JM, Pujol P, Callier P, Cavailles V, Freiss G, Maudelonde T, Brouillet JP: Semiquantitative reverse transcription-polymerase chain reaction to evaluate the expression patterns of genes involved in the oestrogen pathway. J Mol Endocrinol 24: 433-440, 2000
5. Anzick SL, Kononen J, Walker RL, Azorsa DO, Tanner MM, Guan XY, Sauter G, Kallioniemi OP, Trent JM, Meltzer PS: AIB1, a steroid receptor coactivator amplified in breast and ovarian cancer. Science 277: 965-968, 1997
6. Bautista S, Valles H, Walker RL, Anzick S, Zeillinger R, Meltzer P, Theillet C: In breast cancer, amplification of the steroid receptor coactivator gene AIB1 is correlated with estrogen and progesterone receptor positivity. Clin Cancer Res 4: 2925-2929, 1998
7. Bouras T, Southey MC, Venter DJ: Overexpression of the steroid receptor coactivator AIB1 in breast cancer correlates with the absence of estrogen and progesterone receptors and positivity for p53 and HER2/neu. Cancer Res 61: 903-907, 2001
8. Elston CW, Ellis IO: Pathological prognosis factors in breast cancer. The value of histological grade in breast cancer: experience from a large study with long-term follow-up. Histopathology 19: 403-410, 1991
9. Kurebayashi J, Otsuki T, Kunisue H, Tanaka K, Yamamoto S, Sonoo H: Expression levels of estrogen receptor-alpha, estrogen receptor-beta, coactivators, and corepressors in breast cancer. Clin Cancer Res 6: 512-518, 2000
10. Murphy LC, Simon SL, Parkes A, Leygue E, Dotzlaw H, Snell L, Troup S, Adeyinka A, Watson PH: Altered expression of estrogen receptor coregulators during human breast tumorigenesis. Cancer Res 60: 6266-6271, 2000
11. Azorsa DO, Cunliffe HE, Meltzer PS: Association of steroid receptor coactivator AIB1 with estrogen receptor-alpha in breast cancer cells. Breast Cancer Res Treat 70: 89-101, 2001
12. Carroll RS, Brown M, Zhang J, DiRenzo J, De Mora JF, Black PM: Expression of a subset of steroid receptor cofactors is associated with progesterone receptor expression in meningiomas. Clin Cancer Res 6: 3570-3675, 2000
13. Wang Z, Rose DW, Hermanson O, Liu F, Herman T, Wu W, Szeto D, Gleiberman A, Krones A, Pratt K, Rosenfeld R, Glass CK, Rosenfeld MG: Regulation of somatic growth by the p160 coactivator p/CIP. Proc Natl Acad Sci USA 97: 13549-13554, 2000
14. Reiter R, Wellstein A, Riegel AT: An isoform of the coactivator AIB1 that increases hormone and growth factor sensitivity is overexpressed in breast cancer. J Biol Chem 276: 39736-39741, 2001
15. Lauritsen KJ, List HJ, Reiter R, Wellstein A, Riegel AT: A role for TGF-beta in estrogen and retinoid mediated regulation of the nuclear receptor coactivator AIB1 in MCF-7 breast cancer cells. Oncogene 21: 7147-7155, 2002