Bayesian analysis of a previously published genome screen for panic disorder reveals new and compelling evidence for linkage to chromosome 7

American Journal of Medical Genetics - Neuropsychiatric Genetics

Volumn 121 B, Issue 1, 2003, Pages 95-99

  Logue, Mark W ^a,b   Vieland, Veronica J ^a,b   Goedken, Rhinda J ^a   Crowe, Raymond R ^b  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF IOWA   (United States)

Author keywords

Linkage analysis; Probability of linkage

Indexed keywords

ARTICLE; BAYES THEOREM; CHROMOSOME 7; GENE MAPPING; GENETIC ANALYSIS; GENETIC LINKAGE; GENETIC MARKER; GENETIC MODEL; GENETIC SCREENING; GENETIC TRAIT; GENOME; LINKAGE ANALYSIS; PANIC; PRIORITY JOURNAL; PROBABILITY; PUBLICATION;

GENETTA;

EID: 0041318935     PISSN: 15524841     EISSN: 1552485X     Source Type: Journal    
DOI: 10.1002/ajmg.b.20072     Document Type: Article

References (26)

1. Alpert MA, Sabeti M, Kushner MG, Beitman BD, Russell JL, Thiele JR, Mukerji V. 1992. Frequency of isolated panic attacks and panic disorder in patients with the mitral valve prolapse syndrome. Am J Cardiol 69:1489-1490.
2. American Psychiatric Association. 1987. Diagnostic and statistical manual of mental disorders, third edn. Washington, DC: American Psychiatric Association.
3. American Psychiatric Association. 1994. Diagnostic and statistical manual of mental disorders, fourth edn. Washington, DC: American Psychiatric Association.
4. Bartlett CW, Flax JF, Logue MW, Vieland VJ, Bassett AS, Tallal P, Brustowicz LM. 2002. A major susceptibility locus for specific language impairment is located on 13q21. Am J Hum Genet 71:45-55.
5. Crowe RR, Goedken R, Samuelson S, Wilson R, Nelson J, Noyes J-R. 2001. Genome wide survey of panic disorder. Am J Med Genet (Neuropsychiatr Genet) 105:105-109.
6. Disse SR, Abergel E, Berrebi A, Houot A-M, Le Heuzey H-Y, Diebold B, Carpentier LGA, Corvol P, Jeunemaitre X. 1999. Mapping of a first locus for autosomal dominant myxomatous mitral-valve prolapse to chromosome 16p11.2-p12.1. Am J Hum Genet 65:1242-1251.
7. Elston RC, Lange K. 1975. The prior probability of autosomal linkage. Ann Hum Genet 38:341-350.
8. Gorman JM, Goetz RR, Fyer M, King DL, Fyer AJ, Liebowitz MR, Klein DF. 1988. The mitral valve prolapse-panic disorder connection. Psychosom Med 50:114-122.
9. Kessler RC, McGonagle KA, Nelson CB, Hughes M, Eshleman S, Wittchen HU, Kendler KS. 1994. Lifetime and 12 month prevalence of DSM-III-R psychiatric disorders in the United States: Results from the National Comorbidity Survey. Arch Gen Psychiatr 51:8-19.
10. Knowles JA, Fyer AJ, Vieland VJ, Weissman MM, Hodge SE, Heiman GA, Haghighi F, de Jesus GM, Rassnick H, Preud'homme-Rivelli X, Austin T, Cunjak J, Mick S, Fine LD, Woodley KA, Das K, Maier W, Adams PB, Freimer NB, Klein DF, Gilliam TC. 1998. Results of a genome-wide genetic screen for panic disorder. Am J Med Genet (Neuropsychiatr Genet) 81:139-147.
11. Lathrop GM, Lalouel JM. 1984. Easy calculations of lod scores and genetic risks on small computers. Am J Hum Genet 36:460-465.
12. Lathrop GM, Lalouel JM, White RL. 1986. Construction of human linkage maps: Likelihood calculations for multilocus linkage analysis. Genet Epidemiol 3:39-52.
13. Logue MW. 2001. Complications of an unknown genetic model in the presence of heterogeneity for linkage analysis. PhD Thesis. Iowa City, IA: University of Iowa.
14. Morton NE. 1955. Sequential tests for the detection of linkage. Am J Hum Genet 7:277-318.
15. Morton NE. 1998. Significance levels in complex inheritance. Am J Hum Genet 62:690-697.
16. Ott J. 1977. Counting methods (EM algorithm) in human pedigree analysis: Linkage and segregation analysis. Ann Hum Genet 40:443-454.
17. Ott J. 1983. Linkage analysis and family classification under heterogeneity. Ann Hum Genet 47:311-320.
18. Ott J. 1989. Computer-simulation methods in human linkage analysis. Proc Natl Acad Sci USA 86:4175-4178.
19. Robbins LN, Regier DA, editors. 1991. Psychiatric disorders in America: The epidemiological catchment area study. New York: The Free Press.
20. Sivaramakrishnan K, Alexander PJ, Saharsarnamam N. 1994. Prevalence of panic disorder in mitral valve prolapse: A comparative study with a cardiac control group. Acta Psychiatr Scand 89:59-61.
21. Smith CAB. 1963. Testing for heterogeneity of recombination fraction values in human genetics. Ann Hum Genet 27:175-182.
22. Vieland VJ. 1998. Bayesian linkage analysis, or: How I learned to stop worrying and love the posterior probability of linkage. Am J Hum Genet 63:947-954.
23. Vieland VJ, Logue M. 2002. HLODs, trait models, and ascertainment: Implications of admixture for parameter estimation and linkage detection. Hum Hered 53:23-35.
24. Vieland VJ, Wang K, Huang J. 2001. Power to detect linkage in the presence of locus heterogeneity: Comparative evaluation of model-based linkage methods for affected sib pair data. Hum Hered 51:199-208.
25. Wang K, Vieland V, Huang J. 1999. A Bayesian approach to replication of linkage findings. Genet Epidemiol 17(Suppl 1):S749-S754.
26. Wang K, Huang J, Vieland VJ. 2000. The consistency of the posterior probability of linkage. Ann Hum Genet 64:533-553.