Relationship between proliferation of vascular smooth muscle cells and PDGF-AA and PDGFR-α expression in SHRs

Acta Physiologica Sinica

Volumn 54, Issue 2, 2002, Pages 145-148

  Jin, Jun ^a   Zhu, Shan Jun ^a   Zhu, Zhi Ming ^a   Yang, Yong Jian ^a   Ding, Gang ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Platelet derived growth factor; Platelet derived growth factor receptor; Spontaneously hypertension

Indexed keywords

PLATELET DERIVED GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR A; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; PLATELET-DERIVED GROWTH FACTOR A;

ANIMAL; ARTICLE; BIOSYNTHESIS; CELL CULTURE; CELL DIVISION; CYTOLOGY; DRUG EFFECT; HYPERTENSION; MALE; METABOLISM; PATHOPHYSIOLOGY; RAT; SPONTANEOUSLY HYPERTENSIVE RAT; VASCULAR SMOOTH MUSCLE; WISTAR KYOTO RAT;

ANIMALS; CELL DIVISION; CELLS, CULTURED; HYPERTENSION; MALE; MUSCLE, SMOOTH, VASCULAR; PLATELET-DERIVED GROWTH FACTOR; RATS; RATS, INBRED SHR; RATS, INBRED WKY; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR ALPHA;

EID: 0040079856     PISSN: 03710874     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (7)

1. Heldin CH, Westermark B. Mechanism of action and in vivo role of platelet-derived growth factor. Physiol Rev, 1999, 79(4):1283-1316.
2. Inagami T, Kambayashi Y, Ichiki T, Tsuzuki S, Eguchi S, Yamakawa T. Angiotensin II receptors AT1 and AT2: new mechanisms of signaling and antagonistic effects of AT1 and AT2. Jpn Circ J, 1997, 61: 807-813.
3. Fischer JW, Davies MG, Wight TN. Versican is the predominant proteoglycan in flow accelerated neointimal hyperplasia of endothelialized baboon vascular grafts. Circulation, 1998, 98 (suppl I): I-228. Abstract.
4. Nakayama M, Fukuda N, Watanabe Y, Soma M, Hu WY, Kishioka H, Satoh C, Kubo A, Kanmatsuse K. Low dose of eicosapentaenoic acid inhibits the exaggerated growth of vascular smooth muscle cells from spontaneously hypertensive rats through suppression of transforming growth factor-beta. J Hypertens, 1999, 17 (10): 1421-1430.
5. Sabri A, Levy BI, Poitevin P, Caputo L, Faggin E, Marootte F, Rappaport L, Samuel JL. Differential roles of ATI and AT2 receptor subtypes in vascular trophic and phenotypic changes in response to stimulation with angiotensin II. Arterioscler Thromb Vasc Biol, 1997, 17: 257 -264.
6. Parker SB, Dobrian AD, Wade SS, Prewitt RL. AT(1) receptor inhibition does not reduce arterial wall hypertrophy or PDGF-A expression in renal hypertension. Am J Physiol Heart Circ Physiol, 2000, 278 (2): H613-H622.
7. Dobrian A, Wade SS, Prewitt RL. PDGF-A expression correlates with blood pressure and remodeling in 1K1C hypertensive rat arteries. Am J Physiol, 1999, 276 (6 Pt 2):H2159-H2167.