Differential roles of AT1 and AT2 receptor subtypes in vascular trophic and phenotypic changes in response to stimulation with angiotensin II

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 17, Issue 2, 1997, Pages 257-264

  Sabri, Abdelkarim ^a   Levy, Bernard I ^a   Poitevin, Pierre ^a   Caputo, Lidia ^a   Faggin, Elisabetta ^a   Marotte, Françoise ^a   Rappaport, Lydie ^a   Samuel, Jane Lyse ^a,b  

^a INSERM   (France)

^b HÔPITAL LARIBOISIÈRE   (France)

Author keywords

angiotensin II; hypertrophy; losartan; PD123319; smooth muscle cells

Indexed keywords

1 (4 DIMETHYLAMINO 3 METHYLBENZYL) 5 DIPHENYLACETYL 4,5,6,7 TETRAHYDRO 1H IMIDAZO[4,5 C]PYRIDINE 6 CARBOXYLIC ACID; ANGIOTENSIN; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN 2 RECEPTOR; ANGIOTENSIN RECEPTOR; FIBRONECTIN; LOSARTAN; MYOSIN; RECEPTOR SUBTYPE; ANGIOTENSIN II;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTERY INTIMA PROLIFERATION; ARTICLE; BLOOD PRESSURE REGULATION; CONTROLLED STUDY; GENE EXPRESSION REGULATION; HISTOPATHOLOGY; HORMONAL REGULATION; HYPERTENSION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR BINDING; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; ANIMAL; AORTA; BLOOD VESSEL; CORONARY BLOOD VESSEL; DRUG EFFECT; HYPERTROPHY; METABOLISM; PATHOLOGY; PHENOTYPE; PHYSIOLOGY; TUNICA MEDIA; VASCULAR SMOOTH MUSCLE; WISTAR RAT;

ANGIOTENSIN II; ANIMALS; AORTA; BLOOD VESSELS; CORONARY VESSELS; HYPERTROPHY; MALE; MUSCLE, SMOOTH, VASCULAR; PHENOTYPE; RATS; RATS, WISTAR; RECEPTORS, ANGIOTENSIN; TUNICA MEDIA;

EID: 0030614828     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.17.2.257     Document Type: Article

References (11)

1. Mulvany MJ. The structure of the resistance vasculature in essential hypertension. J Hypertens. 1987;5:129-136.
2. Owens GK. Control of hypertrophic versus hyperplastic growth of vascular smooth muscle cells. Am J Physiol. 1989;257:H1755-H1765.
3. Levy BI, Diurez M, Philipe M, Poitevin P, Michel JB. Effect of chronic dihydropyridine (Isradipine) on the large arterial walls of spontaneously hypertensive rats. Circulation. 1994;90:3024-3033.
4. Contard F, Sabri A, Glukhova M, Sartore S, Marotte F, Pomies JP, Schiavi P, Guez D, Samuel JL, Rappaport L. Arterial smooth muscle cell phenotype in stroke-prone spontaneously hypertensive rats. Hypertension. 1993;22:665-676.
5. Pauletto P, Sarzani R, Rappelli A, Pessina AC, Sartore S. Differentiation and growth of vascular smooth muscle cells in experimental hypertension. In: Laragh JH, Brenner BM, eds. Hypertension: Pathophyslology. Diagnosis and Management. New York, NY: Raven Press Ltd; 1995:697-709.
6. Owens GK. Regulation of differentiation of vascular smooth muscle cells. Physiol Rev. 1995;75:487-517.
7. Dzau VJ, Gibbons GH, Pratt RE. Molecular mechanisms of vascular renin-angiotensin system in myointimal hyperplasia. Hypertension. 1991;18(suppl II):II-100-II-105.
8. Crawford DC, Chobanian AV, Brecher P. Angiotensin II induces fibronectin expression associated with cardiac fibrosis in the rat. Circ Res. 1994;74:727-739.
9. Geistefer AAT, Peach MJ, Owens GK. Angiotensin II induces hypertrophy, not hyperplasia, of cultured rat aortic smooth muscle cells. Circ Res. 1988;62:749-756.
10. Berk BC, Vekshtein V, Gordon HM, Tsuda T. Angiotensin H-stimulated protein synthesis in cultured vascular smooth muscle cells. Hypertension. 1989;13:305-314.
11. Hadrava H, Tremblay J, Hamet P. Abnormalities in growth characteristics of aortic smooth muscle cells in spontaneously hypertensive rats. Hypertension. 1989;13:589-597.