Helicobacter pylori-induced interleukin-8 secretion by gastric epithelial cells its relation to protein tyrosine kinase activation

Chinese Journal of Microbiology and Immunology

Volumn 21, Issue 6, 2001, Pages 672-675

  He, Xingxiang ^a   Hu, Pinjin ^a   He, Yao ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

Helicobacter pylori; Interleukin 8; Protein kinase

Indexed keywords

EID: 0040079617     PISSN: 02545101     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (9)

1. Li SD, Kersulyte D, Lindley IJ, et al. Multiple genes in the left half of the cag pathogenicity island of Helicobacter pylori are required for tyrosine kinase-dependent transcription of interleakin-8 in gastric epithelial cells. Infect Immun, 1999, 67(8): 3893-3899.
2. Yang HT, Wu SV, Pichuantes S, et al. High prevalence of cagA-positive strains in Helicobacter pylori-infection, healthy, young Chinese adults. J Gastroenterol Hepatol, 1999, 14: 476-480.
3. Yamaoka Y, Kita M, Kodama T, et al. Chemokines in the gastric mucosa in Helicobacter pylori infection. Gut, 1998, 42: 609-617.
4. Yamaoka Y, Kodama T, Kita M, et al. Relation between clinical presentation, Helicobacter pylori density, interleukin 1β and 8 production, and cagA status. Gut, 1999, 45: 804-811.
5. Crabtree JE, Xiang Z, Lindley IJD, et al. Induction of interleukin-8 secretion from gastric epithelial cells by cagA negative isogenic mutant of Helicobacter pylori. J Clin Pathol, 1995, 48: 967-969.
6. Beales ILP, Calam J. Stimulation of IL-8 production in human gastric epithelial cells by Helicobacter pylori, IL-1β and TNF-α requires tyrosine kinase activity, but not protein kinase C. Cytokine, 1997, 9: 514-520.
7. Segal ED, Lange C, Tompkins LS, et al. Induction of host signal transduction pathways by Helicobacter pylori. Proc Natl Acad Sci USA, 1997, 94: 7595-7599.