The architecture of a water-selective pore in the lipid bilayer visualized by electron crystallography in vitreous ice

Novartis Foundation Symposium

Volumn 245, Issue , 2002, Pages 33-50

  Mitra, Alok K ^a   Ren, Gang ^a   Reddy, Vijay S ^a   Cheng, Anchi ^a   Froger, Alexandrine ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AQP1 PROTEIN, HUMAN; AQUAPORIN; AQUAPORIN 1; BLOOD GROUP ANTIGEN; ICE; ION CHANNEL; WATER;

AMINO ACID SEQUENCE; CHEMICAL STRUCTURE; CHEMISTRY; CRYSTALLOGRAPHY; HUMAN; LIPID BILAYER; METHODOLOGY; MOLECULAR GENETICS; PROTEIN CONFORMATION; PROTEIN SECONDARY STRUCTURE; REVIEW;

AMINO ACID SEQUENCE; AQUAPORIN 1; AQUAPORINS; BLOOD GROUP ANTIGENS; CRYSTALLOGRAPHY; HUMANS; ICE; ION CHANNELS; LIPID BILAYERS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; WATER;

EID: 0040074445     PISSN: None     EISSN: None     Source Type: Book Series    
DOI: None     Document Type: Article

References (35)

1. Agre P 1997 Molecular physiology of water transport: aquaporin nomenclature workshop. Mammalian aquaporins. Biol Cell 89:255-257
2. Agre P, Preston GM, Smith BL et al 1993 Aquaporin CHIP: the archetypal molecular water channel. Am J Physiol 265:F463-F476
3. Brunger AT, Kuriyan J, Karplus M 1987 Crystallographic R factor refinement by molecular dynamics. Science 235:458-460
4. Cheng A, van Hoek AN, Yeager M, Verkman AS, Mitra AK 1997 Three-dimensional organization of a human water channel. Nature 387:627-630
5. Denker BM, Smith BL, Kühajda FP, Agre P 1988 Identification, purification, and partial characterization of a novel Mr 28,000 integral membrane protein from erythrocytes and renal tubules. J Biol Chem 263:15634-15642
6. + conduction and selectivity. Science 280:69-77
7. Engel A, Walz T, Agre P 1994 The aquaporin family of membrane water channels. Curr Opin Struct Biol 4:545-553
8. Foster W, Helm A, Turnbull I et al 2000 Identification of sequence determinants that direct different intracellular folding pathways for aquaporin-1 and aquaporin-4. J Biol Chem 275: 34157-34165
9. Fu D, Libson A, Miercke LJW et al 2000 Structure of a glycerol-conducting channel and the basis for its selectivity. Science 290:481-486
10. Grigorieff N, Ceska TA, Downing KH, Baldwin JM, Henderson R 1996 Electron-crystallographic refinement of the structure of bacteriorhodopsin. J Mol Biol 259:393-421
11. Jones TA, Zou J-Y, Cowans S W, Kjeldgaard M 1991 Improved methods for building protein models in electron density maps and the location of errors in these models. Acta Crystallogr A 47:110-119
12. Jung JS, Preston GM, Smith BL, Guggino WB, Agre P 1994 Molecular structure of the water channel through aquaporin CHIP. The hourglass model. J Biol Chem 269:14648-14654
13. Meinild DA, Klaerke DA, Zeuthen T 1998 Bidirectional water fluxes and specificity for small hydrophilic molecules in aquaporins 0-5. J Biol Chem 273:32446-32451
14. Mitra AK, van Hoek AN, Wiener MC, Verkman AS, Yeager M 1995 The CHIP28 water channel visualized in ice by electron crystallography. Nat Struct Biol 2:726-729
15. Mittl PRE, Deillon C, Sargent D et al 2000 The retro-GCN4 leucine zipper sequence forms a stable three-dimensional structure. Proc Natl Acad Sci USA 97:2562-2566
16. Murata K, Mitsuoka K, Hirai T et al 2000 Structural determinants of water permeation through aquaporin-1. Nature 407:599-605
17. Pao GM, Wu LF, Johnson KD et al 1991 Evolution of the MIP family of integral membrane transport proteins. Mol Microbiol 5:33-37
18. 2 across membranes. J Biol Chem 273:33123-33126
19. Read RJ 1986 Improved fourier coefficients for maps using phases from partial structures with errors. Acta Crystallogr A 42:140-149
20. Ren G, Cheng A, Reddy V, Melnyk P, Mitra, AK 2000a Three-dimensional fold of the human AQP1 water channel determined at 4 Å resolution by electron crystallography of two-dimensional crystals embedded in ice. J Mol Biol 301:369-387
21. Ren G, Cheng A, Melnyk P, Mitra AK 2000b Polymorphism in the packing of aquaporin-1 tetramers in 2D crystals. J Struct Biol 130:45-53
22. Ren G, Reddy VS, Cheng A, Melnyk P, Mitra AK 2001 Visualization of a water-selective pore by electron crystallography in vitreous ice. Proc Natl Acad Sci USA 98:1398-1403
23. Sanner M, Olson AJ, Spehner JC 1996 Reduced surface: an efficient way to compute molecular surfaces. Biopolymers 38:305-320
24. Stillinger FH 1980 Water revisited. Science 209:451-457
25. Unger VM, Schertler GF 1995 Low resolution structure of bovine rhodopsin determined by electron cryo-microscopy. Biophys J 68:1776-1786
26. Upson C, Faulheber TJr, Kamins D et al 1989 The application visualization system: A computational environment for scientific visualization. IEEE Comput Graphic Appl 9:30-42
27. van Hoek AN, Verkman AS 1992 Functional reconstitution of the isolated erythrocyte water channel CHIP28. J Biol Chem 267:18267-18269
28. Verbavatz JM, Brown D, Sabolic I et al 1993 Tetrameric assembly of CHIP28 water channels in liposomes and cell membranes: a freeze-fracture study. J Cell Biol 123:605-618
29. Verkman AS, Mitra AK 2000 Structure and function of aquaporin water channels. Am J Physiol 278:F13-F28
30. Verkman AS, van Hoek AN, Ma T et al 1996 Water transport across mammalian cell membranes. Am J Physiol 270:C12-C30
31. Walz T, Hirai T, Murata K et al 1997 The three-dimensional structure of aquaporin-1. Nature 387:624-627
32. Wistow GJ, Pisano MM, Chepelinsky AB 1991 Tandem sequence repeats in transmembrane channel proteins. Trends Biochem Sci 16:170-171
33. Yool AJ, Stamer WD, Regan JW 1996 Forskolin stimulation of water and cation permeability in aquaporin 1 water channels. Science 273:1216-1218
34. Zeidel ML, Ambudkar SV, Smith BL, Agre P 1992 Reconstitution of functional water channels in liposomes containing purified red cell CHIP28 protein. Biochemistry 31:7436-7440
35. Zeidel ML, Nielsen S, Smith BL, Ambudkar SV, Maunsbach AB, Agre P 1994 Ultrastructure, pharmacologic inhibition, and transport selectivity of aquaporin channel-forming integral protein in proteoliposomes. Biochemistry 33:1606-1615