Phytocystatins and their target enzymes: From molecular biology to practical application: A review

Journal of Food Biochemistry

Volumn 22, Issue 4, 1998, Pages 287-299

  Arai, Soichi ^a   Matsumoto, Ichiro ^b   Abe, Keiko ^b  

^a TOKYO UNIVERSITY OF AGRICULTURE   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0039986152     PISSN: 01458884     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1745-4514.1998.tb00245.x     Document Type: Review

References (34)

1. 2-terminal 21 amino acid residues are not essential for the papain-inhibitory activity of oryzacystatin, a member of the cystatin superfamily. Expression of oryzacystatin cDNA and its truncated fragments in Escherichia coli. J. Biol. Chem. 263, 7655-7659.
2. ABE, K., EMORI, Y., KONDO, H., SUZUKI, K. and ARAI, S. 1987a. Molecular cloning of a cysteine proteinase inhibitor of rice (oryzacystatin).Homology with animal cystatins and transient expression in the ripening process of rice seeds. J. Biol. Chem. 262, 16793-16797.
3. ABE, K., KONDO, H. and ARAI, S. 1987b. Purification and characterization of a rice cysteine proteinase inhibitor. Agric. Biol. Chem. 51, 2763-2768.
4. ABE, K., KONDO, H., EMORI, Y. and ARAI, S. 1991. Oryzacystatins as the first well-defined cystatins of plant origin and their target proteinases in rice seeds. Biomed. Biochim. Acta. 50, 637-641.
5. ABE, M., ABE, K., KURODA, M. and ARAI, S. 1992. Corn kernel cysteine proteinase inhibitor as a novel cystatin superfamily member of plant origin: molecular cloning and expression studies. Eur. J. Biochem. 209, 933-937.
6. AOKI, H., AKAIKE, T., ABE, K., KURODA, M., ARAI, S., OKAMURA, R., NEJI, A. and MAEDA, H. 1995. Antiviral effect of oryzacystatin, a proteinase inhibitor in rice, against herpes simplex virus type 1 in vitro and in vivo. Antimicrob. Agent. Chemother. 39, 846-849.
7. APPLEBAUM, S. W. 1985. Biochemistry of Digestion. In Comprehensive Insect Physiology, Biochemistry and Pharmacology (G.A. Kerkut and L.I. Gilbelt, eds.) Vol. 4, 279-311, Pergamon Press, New York.
8. ARAI, S. and FUZIMAKI, M. 1991. Enzymatic modification of proteins with special reference to improving their functional properties. In Food Enzymology (P.F. Fox, ed.) pp. 83-104, Elsevier Applied Science, London.
9. ARAI, S., KURODA, M., MATSUMOTO, I., WATANABE, H. and ABE, K. 1995. Molecular cloning of cereal cystatins and evaluation of their antiviral and antipest effects. In Genetically Modified Foods (ACS Symposium Series 605) (K.-H. Engel, G.R. Takeoka and R. Teranishi, eds.) pp. 124-133, American Chemical Society.
10. ARAI, S., WATANABE, H., KONDO, H., EMORI, Y. and ABE, K. 1991. Papain-inhibitory activity of oryzacystatin, a rice seed cysteine proteinase inhibitor, depends on the central Gln-Val-Val-Ala-Gly region conserved among cystatin superfamily members. J. Biochem. 109, 294-298.
11. BARRET, A.J. 1972. A new assay for cathepsin B1 and other thiol proteinases. Anal. Biochem. 47, 280-293.
12. DOMOTO, C., WATANABE, H., ABE, M., ABE, K. and ARAI, S. 1995. Isolation and characterization of two distinct cDNA clones encoding corn seed cysteine proteinases. Biochim. Biophys. Acta 1263, 241-244.
13. FUNAKI, J., ABE, K., HAYABUCHI, H. and ARAI, S. 1991. Modulating the conditioning of meat by the use of oryzacystatin, a cysteine proteinase inhibitor of rice seed origin. J. Food Biochemistry 15, 253-262.
14. HANAHAN, D. 1983. Studies on transformation of Escherichia coli with plasmids. J. Mol. Biol. 166, 557-580.
15. HOSOYAMA, H., IRIE, K., ABE, K. and ARAI, S. 1994. Oryzacystatin exogenously introduced into protoplasts and regeneration of a transgenic rice. Biosci. Biotech. Biochem. 58, 1500-1506.
16. HOSOYAMA, H., IRIE, K., ABE, K. and ARAI, S. 1995. Introduction of a chimeric gene encoding an oryzacystatin-β-glucuronidase fusion protein into rice protoplasts and regeneration of transformed plants. Plant Cell Rep. 15, 174-177.
17. IRIE, K., HOSOYAMA, H., TAKEUCHI, T., IWABUCHI, K., WATANABE, H., ABE, M., ABE, K. and ARAI, S. 1996. Transgenic rice established to express corn cystatin exhibits strong inhibitory activity against insect gut proteinases. Plant Mol. Biol. 30, 149-157.
18. IVANHOFF, L.A., TOWATANI, T., RAY, J., KORANT, B.D. and PETTEWAY, S.R. 1986. Expression and site-specific mutagenesis of the poliovirus 3C protease in Escherichia coli. Proc. Natl. Acad. Sci. USA 83, 5392-53967.
19. KONDO, H., ABE, K., EMORI, Y. and ARAI, S. 1991. Gene organization of oryzacystatin-II, a new cystatin superfamily member of plant origin, is closely related to that of oryzacystatin-I but different from those of animal cystatins. FEBS Lett. 278, 87-90.
20. KONDO, H., ABE, K., NISHIMURA, I., WATANABE, H., EMORI, Y. and ARAI, S. 1990. Two distinct cystatin species in rice seeds with different specificities against cysteine proteinases. Molecular cloning, expression, and biochemical studies on oryzacystatin-II. J. Biol. Chem. 265, 15832-15837.
21. KONDO, H., EMORI, Y., ABE, K., SUZUKI, K. and ARAI, S. 1989. Cloning and sequence analysis of the genomic DNA fragment encoding oryzacystatin. Gene 81, 259-265.
22. KONDO, H., IJIRI, S., ABE, K., MAEDA, H. and ARAI, S. 1992. Inhibitory effect of oryzacystatins and a truncation mutant on the replication of poliovirus in infected Vero cells. FEBS Lett. 299, 48-50.
23. KURODA, M., ISHIMOTO, M., SUZUKI, K., KONDO, H., ABE, K., KITAMURA, K. and ARAI, S. 1996. Oryzacystatins exhibit growth-inhibitory and lethal effects on different species of bean insect pests, Callosobruchus chinensis (Coleoptera) and Riptortus clavatus (Hemiptera). Biosci. Biotech. Biochem. 60, 209-212.
24. KURODA, M., KIYOSAKI, T., ARAI, S. and ABE, K. 1997. Purification and Properties of a cysteine proteinase occurring dormant wheat seeds. Biosci. Biotech. Biochem. 61, 732-734.
25. LIANG, C., BROOKHART, G., FENG, G.H., REECK, G.R. and KRAMER, K.J. 1991. Inhibition of digestive proteinases of stored grain coleoptera by oryzacystatin, a cysteine proteinase inhibitor from rice seed. FEBS Lett 278, 139-142.
26. MATSUMOTO, I., EMORI, Y., ABE, K. and ARAI, S. 1997. Characterization of a gene family encoding cysteine proteinases of Sitophilus zeamais (maize weevil), and analysis of the protein distribution in various tissues including alimentary tract and germ cells. J. Biochem. 121, 464-476.
27. MATSUMOTO, I., WATANABE, H., ABE, K., ARAI, S. and EMORI, Y. 1995. A putative digestive cysteine proteinase from Drosophila melanogaster is predominantly expressed in the embryonic and larval midgut. Eur. J. Biochim. 227, 582-587.
28. MISAKA, T., KURODA, M., IWABUCHI, K., ABE, K. and ARAI, S. 1996. Soyacystatin, a novel cysteine proteinase inhibitor in soybean, is distinct in protein structure and gene organization from other cystatins of animal and plant origin. Eur. J. Biochem. 240, 609-614.
29. ROGERS, J.C., DEAN, D. and HECK, G.R. 1995. Aleurain: a barley thiol protease closely related to mammalian cathepsin H. Proc. Natl. Acad. Sci. USA 82, 6512-6518.
30. SCHECHTER, I. and BERGER, A. 1967. On the size of the active site in proteases. I. papain. Biochem. Biophys. Res. Commun. 27, 157-162.
31. SKRIVER, K., OLSEN, F.L., ROGERS, J.C. and MUNDY, J. 1991. Cis-acting elements responsive to gibberellin and its antagonist abscisic acid. Proc. Natl. Acad. Sci. USA 88, 7266-7270.
32. TURK, V. and BODE, W. 1991. The cystatins: protein inhibitors of cysteine proteinases. FEBS Lett. 255, 213-219.
33. WATANABE, H., ABE, K. and ARAI, S. 1992. Gibberellin-responsive gene expression taking place with oryzains α and γ as cysteine proteinases of rice seeds. Biosci. Biotech. Biochem. 56, 1154-1155.
34. WATANABE, H., ABE, K., EMORI, Y., HOSOYAMA, H. and ARAI, S. 1991. Molecular cloning and gibberellin-induced expression of multiple cysteine proteinases of rice seeds (oryzains). J. Biol. Chem. 266, 16897-16902.