Expression of anti-Z-DNA single chain antibody variable fragment on the filamentous phage surface

Brazilian Journal of Medical and Biological Research

Volumn 33, Issue 5, 2000, Pages 569-579

  Maranhao, A Q ^a   Brigido M M ^a  

^a UNIVERSITY OF BRASILIA   (Brazil)

Author keywords

Anti nucleic acid antibodies; Biopanning; Phage display; scFv; Z DNA

Indexed keywords

AMINO ACID; ANTIBODY; IMMUNOGLOBULIN FRAGMENT; PEPTIDE LIBRARY; VIRUS DNA;

AMINO ACID SEQUENCE; ARTICLE; BACTERIOPHAGE; BIOSYNTHESIS; CHEMISTRY; GENE AMPLIFICATION; GENE FUSION; GENE LIBRARY; GENE VECTOR; GENETICS; IMMUNOLOGY; METABOLISM; METHODOLOGY; MOLECULAR CLONING; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; POLYMERASE CHAIN REACTION;

AMINO ACID SEQUENCE; AMINO ACIDS; ANTIBODIES; ARTIFICIAL GENE FUSION; BACTERIOPHAGES; BASE SEQUENCE; CLONING, MOLECULAR; DNA, VIRAL; GENE AMPLIFICATION; GENE LIBRARY; GENETIC VECTORS; IMMUNOGLOBULIN FRAGMENTS; MOLECULAR SEQUENCE DATA; PEPTIDE LIBRARY; POLYMERASE CHAIN REACTION;

EID: 0039333356     PISSN: 0100879X     EISSN: 1414431X     Source Type: Journal    
DOI: 10.1590/S0100-879X2000000500012     Document Type: Article

References (22)

1. Polymenis M & Stollar BD (1994). Critical binding site amino acid residues of anti-Z-DNA single chain Fv molecules: the role of H and L chain CDR3 and relationship to autoantibody activity. Journal of Immunology, 152: 5318-5329.
2. Brigido MM & Stollar BD (1991). Two induced anti-Z-DNA monoclonal antibodies use VH gene segments related to those of anti-DNA autoantibodies. Journal of Immunology, 146: 2005-2009.
3. Parmley SF & Smith GP (1988). Antibody selectable filamentous fd phage vectors: affinity purification of target genes. Gene, 73: 305-318.
4. H gene segments rearranged in vitro. Journal of Molecular Biology, 227: 381-388.
5. Hoogenboom HR, de Bruïne AP, Hufton SE, Hoet RM, Arenas JW & Roovers RC (1998). Antibody phage display technology and its applications. Immunotechnology, 4: 1-20.
6. Hawkins RE, Russel SR & Winter G (1992) Selection of phage antibodies of a structural epitope by using a peptide library displayed on filamentous bacteriophage. Journal of immunology, 153: 724-729.
7. Garrad LJ & Henner DJ (1993). Selection of an anti-IGF-1 Fab from a Fab phage display library created by mutagenesis of multiple CDR loops Gene, 128: 103-109.
8. Ward ES (1995). VH shuffling can be used to convert a Fv fragment of anti-hen egg lysozyme specificity to one that recognizes a T cell receptor Vα. Molecular Immunology, 32: 147-156.
9. Smith GP (1993). Surface display and peptide libraries Gene, 128: 1-2.
10. Lowman HB (1997). Bacteriophage display and discovery of peptides leads for drug development. Annual Review of Biophysics and Biomolecular Structure, 26: 401-424.
11. Smith GP & Scott JK (1993). Libraries of peptides and proteins displayed on filamentous phage. Methods in Enzymology, 217: 228-257.
12. Breitling F, Dübel S, Seehaus T, Fuchs P, Braunagel M, Klewinghaus I & Little M (1991). A surface expression vector for antibody screening. Gene, 104: 147-153.
13. Lowman HB, Bass SH, Simpson N & Wells JA (1991). Selecting high-affinity binding proteins by monovalent phage display. Biochemistry. 30: 10832-10838.
14. Makowski L (1993). Structural constraints of the display of foreign peptides on filamentous bacteriophages. Gene, 128: 5-11.
15. Wells JA (1996). Hormone mimicry. Science, 273: 449-450.
16. Sambrook J, Fritsch EF & Maniatis T (1989). Molecular Cloning - A Laboratory Manual. 2nd edn. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
17. L gene segments in the specific binding of antibody to Z-DNA, analyzed with recombinant single chain Fv molecules. Journal of Immunology. 150: 469-475.
18. Brigido MM, Baradi CRM, Bonjardin CA, Santos CLS, Junqueira ML & Brentam RR (1991). Nucleotide sequence of a variant protein A of Staphylococcus aureus suggests molecular diversity among strains. Journal of Basic Microbiology. 31: 337-345.
19. Whringhton NC, Farrell FX, Chang R, Kashyap AK, Barbone FP, Mulcahy LS, Johnson DL, Barrett RW, Jolliffe LK & Dower WJ (1996). Small peptides as potent mimetic of the protein hormone erythropoietin. Science. 273: 458-463
20. Younderian P (1988). Promoter strength: more is less. Trends in Genetics, 4: 327-328.
21. Posner B, Smiley J, Lee I & Benkovic S (1994). Catalytic antibodies: perusing combinatorial libraries. Trends in Biochemical Sciences, 19: 145-150.
22. Stollar BD (1992). Immunochemical analyses of nucleic acids. Progress in Nucleic Acid Research and Molecular Biology, 49: 39-77.