The Danish PET/depression project: Cognitive function and regional cerebral blood flow

Acta Psychiatrica Scandinavica

Volumn 108, Issue 1, 2003, Pages 32-40

  Ravnkilde, Barbara ^a   Videbech, P ^a   Clemmensen, K ^a   Egander, A ^a   Rasmussen, N A ^a   Gjedde, A ^a   Rosenberg, R ^a   Gade, A ^b  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Cognition; Depression; Magnetic resonance imaging; Neuropsychological tests; Regional blood flow; Tomography, emission computed

Indexed keywords

ADULT; AGED; ARTICLE; BRAIN BLOOD FLOW; BRAIN FUNCTION; BRAIN MAPPING; CLINICAL ARTICLE; COGNITION; CONTROLLED STUDY; DENMARK; FEMALE; HUMAN; LINEAR REGRESSION ANALYSIS; MAJOR DEPRESSION; MALE; NEUROPSYCHOLOGICAL TEST; NUCLEAR MAGNETIC RESONANCE IMAGING; POSITRON EMISSION TOMOGRAPHY; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; SCORING SYSTEM;

ADOLESCENT; ADULT; AGED; BRAIN; CEREBROVASCULAR CIRCULATION; COGNITION DISORDERS; DENMARK; DEPRESSIVE DISORDER; FEMALE; HUMANS; LINEAR MODELS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS; REGIONAL BLOOD FLOW; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 0038803890     PISSN: 0001690X     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-0447.2003.00131.x     Document Type: Article

References (38)

1. RAVNKILDE B, VIDEBECH P, CLEMMENSEN K, EGANDER A, RASMUSSEN NA, ROSENBERG R. Cognitive deficits in major depression. Scand J Psychol 2002;43:239-251.
2. DREVETS WC. Neuroimaging and neuropathological studies of depression: implications for the cognitive-emotional features of mood disorders. Curr Opin Neurobiol 2001;11:240-249.
3. VIDEBECH P. MRI findings in patients with affective disorder: a meta-analysis. Acta Psychiatr Scand 1997;96:157-168.
4. VIDEBECH P, RAVNKILDE B, FIIRGAARD B et al. Structural brain abnormalities in unselected in-patients with major depression. Acta Psychiatr Scand 2001;103:282-286.
5. VIDEBECH P, RAVNKILDE B, PEDERSEN AR et al. The Danish PET/depression Project: PET Findings in patients with major depression. Psychol Med 2001;7:1147-1158.
6. VIDEBECH P. PET measurements of brain glucose metabolism and blood flow in major depressive disorder: a critical review. Acta Psychiatr Scand 2000;101:11-20.
7. BAKER SC, FRITH CD, DOLAN RJ. The interaction between mood and cognitive function studied with PET. Psychol Med 1997;27:565-578.
8. BENCH CJ, FRITH CD, GRASBY PM et al. Investigations of the functional anatomy of attention using the Stroop test. Neuropsychologia 1993;31:907-922.
9. ELLIOTT R, BAKER SC, ROGERS RD et al. Prefrontal dysfunction in depressed patients performing a complex planning task: a study using positron emission tomography. Psychol Med 1997;27:931-942.
10. PHILPOT MP, BANERJEE S, NEEDHAM BENNETT H, COSTA DC, ELL PJ. 99mTc-HMPAO single photon emission tomography in late life depression: a pilot study of regional cerebral blood flow at rest and during a verbal fluency task. J Affect Disord 1993;28:233-240.
11. VIDEBECH P, RAVNKILDE B, KRISTENSEN S et al. The Danish PET/depression project: poor verbal fluency performance despite normal prefrontal activation in patients with major depression, in press.
12. DOLAN RJ, BENCH CJ, BROWN RG, SCOTT LC, FRACKOWIAK RSJ. Neuropsychological dysfunction in depression: the relationship to regional cerebral blood flow. Psychol Med 1994;24:849-857.
13. BENCH CJ, FRISTON KJ, BROWN RG, FRACKOWIAK RS, DOLAN RJ. Regional cerebral blood flow in depression measured by positron emission tomography: the relationship with clinical dimensions. Psychol Med 1993;23:579-590.
14. AUSTIN MP, DOUGALL N, ROSS M et al. Single photon emission tomography with 99mTc-exametazime in major depression and the pattern of brain activity underlying the psychotic/neurotic continuum. J Affect Disord 1992;26:31-43.
15. AWATA S, ITO H, KONNO M et al. Regional cerebral blood flow abnormalities in late-life depression: relation to refractoriness and chronification. Psychiatry Clin Neurosci 1998;52:97-105.
16. VIDEBECH P, RAVNKILDE B, PEDERSEN TH et al. The Danish PET/depression project: clinical symptoms and cerebral blood flow. A regions-of-interest analysis. Acta Psychiatr Scand 2002;106:35-44.
17. BROWN RG, SCOTT LC, BENCH CJ, DOLAN RJ. Cognitive function in depression: its relationship to the presence and severity of intellectual decline. Psychol Med 1994;24:829-847.
18. BENCH CJ, FRISTON KJ, BROWN RG, SCOTT LC, FRACKOWIAK RS, DOLAN RJ. The anatomy of melancholia-focal abnormalities of cerebral blood flow in major depression. Psychol Med 1992;22:607-615.
19. SPITZER RL, WILLIAMS JB, GIBBON M, FIRST MB. The Structured Clinical Interview for DSM-III-R (SCID). I: history, rationale, and description. Arch Gen Psychiatry 1992;49:624-629.
20. HAMILTON M. Development of a rating scale for primary depressive illness. Br J Soc Clin Psychol 1967;6:278-96.
21. MAES M, DIERCKX R, MELTZER HY et al. Regional cerebral blood flow in unipolar depression measured with Tc-99m-HMPAO single photon emission computed tomography: negative findings. Psychiatry Res 1993;50:77-88.
22. MARTINOT JL, HARDY P, FELINE A et al. Left prefrontal glucose hypometabolism in the depressed state: a confirmation. Am J Psychiatry 1990;147:1313-1317.
23. EVERITT BS. Multivariate analysis 1: the analysis of covariances and correlations (principal components and exploratory factor analysis). Making sense of statistics in psychology: a second-level course. NY: Oxford University Press, 1996:215-225.
24. TALAIRACH J, TOURNOUX P. Co-planar stereotaxic atlas of the human brain. Stuttgart: Georg Thieme Verlag, 1988.
25. TALAIRACH J, TOURNOUX P. Co-planar stereotaxic atlas of the human brain. 3-dimensional proportional system: an approach to cerebral imaging. 1st edn. Stuttgart: Thieme, 1988.
26. CABEZA R, NYBERG L. Imaging cognition II: an empirical review of 275 PET and fMRI studies. J Cogn Neurosci 2000;12:1-47.
27. RAVNKILDE B, VIDEBECH P, ROSENBERG R, GJEDDE A, GADE A. Putative tests of frontal lobe function: a PET-study of brain activation during Stroop's test and verbal fluency. J Clin Exp Neuropsychol 2002;24:534-547.
28. BOTVINICK M, NYSTROM LE, FISSELL K, CARTER CS, COHEN JD. Conflict monitoring versus selection-for-action in anterior cingulate cortex. Nature 1999;402:179-181.
29. PETERSON BS, SKUDLARSKI P, GATENBY JC, ZHANG H, ANDERSON AW, GORE JC. An fMRI study of Stroop word-color interference: evidence for cingulate subregions subserving multiple distributed attentional systems. Biol Psychiatry 1999;45:1237-1258.
30. PARDO JV, PARDO PJ, JANER KW, RAICHLE ME. The anterior cingulate cortex mediates processing selection in the Stroop attentional conflict paradigm. Proc Natl Acad Sci USA 1990;87:256-259.
31. DOLAN RJ, BENCH CJ, BROWN RG, SCOTT LC, FRISTON KJ, FRACKOWIAK RSJ. Regional cerebral blood flow abnormalities in depressed patients with cognitive impairment. J Neurol Neurosurg Psychiatry 1992;55:768-773.
32. VIDEBECH P, RAVNKILDE B, EGANDER A et al. The Danish PET/depression project: performance on Stroop's test linked to White Matter Lesions in the Brain. Submitted for publication 2003.
33. ROGERS MA, BRADSHAW JL, PANTELIS C, PHILLIPS JG. Frontostriatal deficits in unipolar major depression. Brain Res Bull 1998;47:297-310.
34. GRAFMAN J. Conceptualizing functional neuroplasticity. J Commun Disord 2000;33:345-355.
35. GRADY CL. Functional brain imaging and age-related changes in cognition. Biol Psychol 2000;54:259-281.
36. ANDREASEN NC, O'LEARY DS, ARNDT S et al. I. PET studies of memory: novel and practiced free recall of complex narratives. Neuroirnage 1995;2:284-295.
37. ANDREASEN NC, O'LEARY DS, CIZADLO T et al. II. PET studies of memory: novel versus practiced free recall of word lists. Neuroimage 1995;2:296-305.
38. HUND-GEORGIADIS M, VON CRAMON DY. Motor-learning-related changes in piano players and non-musicians revealed by functional magnetic-resonance signals. Exp Brain Res 1999;125:417-425.