Rapid gas chromatographic-mass spectrometric diagnosis of dihydropyrimidine dehydrogenase deficiency and dihydropyrimidinase deficiency

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 792, Issue 1, 2003, Pages 107-115

  Kuhara, Tomiko ^a   Ohdoi, Chie ^a   Ohse, Morimasa ^a   Van Kuilenburg, André B P ^a   Van Gennip, Albert H ^b,c   Sumi, Satoshi ^d   Ito, Tetsuya ^d   Wada, Yoshiro ^d   Matsumoto, Isamu ^a  

^a KANAZAWA MEDICAL UNIVERSITY   (Japan)

^b UNIVERSITY OF AMSTERDAM   (Netherlands)

^c Department of Clinical Chemistry ^*  (Netherlands)

^d NAGOYA CITY UNIV MEDICAL SCHOOL   (Japan)

Author keywords

Dihydropyrimidinase; Dihydropyrimidine dehydrogenase; Enzymes

Indexed keywords

ENZYMES; GAS CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLISM; MUTAGENESIS; PATIENT TREATMENT; TUMORS;

GENETIC DISORDERS;

BIOMEDICAL ENGINEERING;

5 HYDROXYMETHYLURACIL; DIHYDROPYRIMIDINASE; DIHYDROPYRIMIDINE DEHYDROGENASE; DIHYDROTHYMINE; DIHYDROURACIL; THYMINE; THYMINE DERIVATIVE; UNCLASSIFIED DRUG; URACIL;

ADULT; BIOACCUMULATION; CHILD; CLINICAL ARTICLE; CONFERENCE PAPER; CONTROLLED STUDY; DIHYDROPYRIMIDINASE DEFICIENCY; DIHYDROPYRIMIDINE DEHYDROGENASE DEFICIENCY; DNA DETERMINATION; ENZYME ASSAY; GAS CHROMATOGRAPHY; GENE MUTATION; HUMAN; INBORN ERROR OF METABOLISM; INFANT; MASS SPECTROMETRY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SEPARATION TECHNIQUE; STANDARD; SYMPTOM; URINALYSIS; URINARY EXCRETION; URINE LEVEL;

EID: 0038798799     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1570-0232(03)00044-8     Document Type: Conference Paper

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